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1782 related items for PubMed ID: 9794795

  • 1. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 2. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG, Schweigart J, Kehrmann J, Ehlting C, Schaper F, Heinrich PC, Häussinger D.
    J Immunol; 2003 Jul 01; 171(1):257-66. PubMed ID: 12817006
    [Abstract] [Full Text] [Related]

  • 3. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H, Baumann H.
    Mol Cell Biol; 1999 Aug 01; 19(8):5326-38. PubMed ID: 10409724
    [Abstract] [Full Text] [Related]

  • 4. Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
    Anhuf D, Weissenbach M, Schmitz J, Sobota R, Hermanns HM, Radtke S, Linnemann S, Behrmann I, Heinrich PC, Schaper F.
    J Immunol; 2000 Sep 01; 165(5):2535-43. PubMed ID: 10946280
    [Abstract] [Full Text] [Related]

  • 5. SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
    Lehmann U, Schmitz J, Weissenbach M, Sobota RM, Hortner M, Friederichs K, Behrmann I, Tsiaris W, Sasaki A, Schneider-Mergener J, Yoshimura A, Neel BG, Heinrich PC, Schaper F.
    J Biol Chem; 2003 Jan 03; 278(1):661-71. PubMed ID: 12403768
    [Abstract] [Full Text] [Related]

  • 6. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
    Heinrich PC, Behrmann I, Müller-Newen G, Schaper F, Graeve L.
    Biochem J; 1998 Sep 01; 334 ( Pt 2)(Pt 2):297-314. PubMed ID: 9716487
    [Abstract] [Full Text] [Related]

  • 7. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells.
    Kim H, Hawley TS, Hawley RG, Baumann H.
    Mol Cell Biol; 1998 Mar 01; 18(3):1525-33. PubMed ID: 9488469
    [Abstract] [Full Text] [Related]

  • 8. The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling.
    Fischer P, Lehmann U, Sobota RM, Schmitz J, Niemand C, Linnemann S, Haan S, Behrmann I, Yoshimura A, Johnston JA, Müller-Newen G, Heinrich PC, Schaper F.
    Biochem J; 2004 Mar 01; 378(Pt 2):449-60. PubMed ID: 14611646
    [Abstract] [Full Text] [Related]

  • 9. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L, Maassen BG, Radtke S, Behrmann I, Schaper F, Heinrich PC, Graeve L, Gatsios P.
    FEBS Lett; 2000 Jul 28; 478(1-2):100-4. PubMed ID: 10922477
    [Abstract] [Full Text] [Related]

  • 10. Shc mediates IL-6 signaling by interacting with gp130 and Jak2 kinase.
    Giordano V, De Falco G, Chiari R, Quinto I, Pelicci PG, Bartholomew L, Delmastro P, Gadina M, Scala G.
    J Immunol; 1997 May 01; 158(9):4097-103. PubMed ID: 9126968
    [Abstract] [Full Text] [Related]

  • 11. Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells.
    Halfter H, Postert C, Friedrich M, Ringelstein EB, Stögbauer F.
    Brain Res Mol Brain Res; 2000 Sep 15; 80(2):198-206. PubMed ID: 11038252
    [Abstract] [Full Text] [Related]

  • 12. Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited.
    Friederichs K, Schmitz J, Weissenbach M, Heinrich PC, Schaper F.
    Eur J Biochem; 2001 Dec 15; 268(24):6401-7. PubMed ID: 11737194
    [Abstract] [Full Text] [Related]

  • 13. Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.
    Fairlie WD, De Souza D, Nicola NA, Baca M.
    Biochem J; 2003 Jun 01; 372(Pt 2):495-502. PubMed ID: 12593670
    [Abstract] [Full Text] [Related]

  • 14. Different protein turnover of interleukin-6-type cytokine signalling components.
    Siewert E, Müller-Esterl W, Starr R, Heinrich PC, Schaper F.
    Eur J Biochem; 1999 Oct 01; 265(1):251-7. PubMed ID: 10491180
    [Abstract] [Full Text] [Related]

  • 15. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.
    Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F.
    J Biol Chem; 2000 Apr 28; 275(17):12848-56. PubMed ID: 10777583
    [Abstract] [Full Text] [Related]

  • 16. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.
    Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030
    [Abstract] [Full Text] [Related]

  • 17. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
    Badache A, Hynes NE.
    Cancer Res; 2001 Jan 01; 61(1):383-91. PubMed ID: 11196191
    [Abstract] [Full Text] [Related]

  • 18. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.
    Kim HY, Park EJ, Joe EH, Jou I.
    J Immunol; 2003 Dec 01; 171(11):6072-9. PubMed ID: 14634121
    [Abstract] [Full Text] [Related]

  • 19. IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.
    Ogata A, Chauhan D, Teoh G, Treon SP, Urashima M, Schlossman RL, Anderson KC.
    J Immunol; 1997 Sep 01; 159(5):2212-21. PubMed ID: 9278309
    [Abstract] [Full Text] [Related]

  • 20. Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
    Novotny-Diermayr V, Lin B, Gu L, Cao X.
    J Biol Chem; 2005 Apr 01; 280(13):12747-57. PubMed ID: 15677447
    [Abstract] [Full Text] [Related]

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