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Journal Abstract Search

339 related items for PubMed ID: 9802339

  • 21. Rat dihydroorotate dehydrogenase: isolation of the recombinant enzyme from mitochondria of insect cells.
    Knecht W, Altekruse D, Rotgeri A, Gonski S, Löffler M.
    Protein Expr Purif; 1997 Jun; 10(1):89-99. PubMed ID: 9179295
    [Abstract] [Full Text] [Related]

  • 22. The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.
    Cherwinski HM, Cohn RG, Cheung P, Webster DJ, Xu YZ, Caulfield JP, Young JM, Nakano G, Ransom JT.
    J Pharmacol Exp Ther; 1995 Nov; 275(2):1043-9. PubMed ID: 7473131
    [Abstract] [Full Text] [Related]

  • 23. Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity.
    Baldwin J, Farajallah AM, Malmquist NA, Rathod PK, Phillips MA.
    J Biol Chem; 2002 Nov 01; 277(44):41827-34. PubMed ID: 12189151
    [Abstract] [Full Text] [Related]

  • 24. Mechanism of action of leflunomide in rheumatoid arthritis.
    Fox RI.
    J Rheumatol Suppl; 1998 Jul 01; 53():20-6. PubMed ID: 9666414
    [Abstract] [Full Text] [Related]

  • 25. Synthesis, structure-activity relationships, and pharmacokinetic properties of dihydroorotate dehydrogenase inhibitors: 2-cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'-(trifluoromethyl)phenyl ] propenamide and related compounds.
    Kuo EA, Hambleton PT, Kay DP, Evans PL, Matharu SS, Little E, McDowall N, Jones CB, Hedgecock CJ, Yea CM, Chan AW, Hairsine PW, Ager IR, Tully WR, Williamson RA, Westwood R.
    J Med Chem; 1996 Nov 08; 39(23):4608-21. PubMed ID: 8917650
    [Abstract] [Full Text] [Related]

  • 26. Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide.
    Bruneau JM, Yea CM, Spinella-Jaegle S, Fudali C, Woodward K, Robson PA, Sautès C, Westwood R, Kuo EA, Williamson RA, Ruuth E.
    Biochem J; 1998 Dec 01; 336 ( Pt 2)(Pt 2):299-303. PubMed ID: 9820804
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  • 28. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.
    Doscas ME, Williamson AJ, Usha L, Bogachkov Y, Rao GS, Xiao F, Wang Y, Ruby C, Kaufman H, Zhou J, Williams JW, Li Y, Xu X.
    Neoplasia; 2014 Oct 01; 16(10):824-34. PubMed ID: 25379019
    [Abstract] [Full Text] [Related]

  • 29. In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.
    Xu X, Blinder L, Shen J, Gong H, Finnegan A, Williams JW, Chong AS.
    J Immunol; 1997 Jul 01; 159(1):167-74. PubMed ID: 9200452
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  • 31. Redoxal as a new lead structure for dihydroorotate dehydrogenase inhibitors: a kinetic study of the inhibition mechanism.
    Knecht W, Löffler M.
    FEBS Lett; 2000 Feb 04; 467(1):27-30. PubMed ID: 10664450
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  • 33. Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases.
    Herrmann ML, Schleyerbach R, Kirschbaum BJ.
    Immunopharmacology; 2000 May 04; 47(2-3):273-89. PubMed ID: 10878294
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  • 35. Leflunomide: mode of action in the treatment of rheumatoid arthritis.
    Breedveld FC, Dayer JM.
    Ann Rheum Dis; 2000 Nov 04; 59(11):841-9. PubMed ID: 11053058
    [Abstract] [Full Text] [Related]

  • 36. Catalytic enzyme histochemistry and biochemical analysis of dihydroorotate dehydrogenase/oxidase and succinate dehydrogenase in mammalian tissues, cells and mitochondria.
    Löffler M, Becker C, Wegerle E, Schuster G.
    Histochem Cell Biol; 1996 Feb 04; 105(2):119-28. PubMed ID: 8852433
    [Abstract] [Full Text] [Related]

  • 37. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase.
    Boa AN, Canavan SP, Hirst PR, Ramsey C, Stead AM, McConkey GA.
    Bioorg Med Chem; 2005 Mar 15; 13(6):1945-67. PubMed ID: 15727850
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  • 39. New inhibitors of dihydroorotate dehydrogenase (DHODH) based on the 4-hydroxy-1,2,5-oxadiazol-3-yl (hydroxyfurazanyl) scaffold.
    Lolli ML, Giorgis M, Tosco P, Foti A, Fruttero R, Gasco A.
    Eur J Med Chem; 2012 Mar 15; 49():102-9. PubMed ID: 22245049
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