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Journal Abstract Search


158 related items for PubMed ID: 9808564

  • 1. Residues Glu2181-Val2243 contain a major determinant of the inhibitory epitope in the C2 domain of human factor VIII.
    Healey JF, Barrow RT, Tamim HM, Lubin IM, Shima M, Scandella D, Lollar P.
    Blood; 1998 Nov 15; 92(10):3701-9. PubMed ID: 9808564
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  • 2. Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII.
    Healey JF, Lubin IM, Nakai H, Saenko EL, Hoyer LW, Scandella D, Lollar P.
    J Biol Chem; 1995 Jun 16; 270(24):14505-9. PubMed ID: 7540171
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  • 3. A role for the C2 domain of factor VIII in binding to von Willebrand factor.
    Saenko EL, Shima M, Rajalakshmi KJ, Scandella D.
    J Biol Chem; 1994 Apr 15; 269(15):11601-5. PubMed ID: 7512568
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  • 4. Elimination of a major inhibitor epitope in factor VIII.
    Lubin IM, Healey JF, Scandella D, Runge MS, Lollar P.
    J Biol Chem; 1994 Mar 25; 269(12):8639-41. PubMed ID: 7510693
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  • 6. A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine.
    Shima M, Scandella D, Yoshioka A, Nakai H, Tanaka I, Kamisue S, Terada S, Fukui H.
    Thromb Haemost; 1993 Mar 01; 69(3):240-6. PubMed ID: 7682339
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  • 9. Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site.
    Pratt KP, Qian J, Ellaban E, Okita DK, Diethelm-Okita BM, Conti-Fine B, Scott DW.
    Thromb Haemost; 2004 Sep 01; 92(3):522-8. PubMed ID: 15351848
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  • 10. Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules.
    Barrow RT, Healey JF, Gailani D, Scandella D, Lollar P.
    Blood; 2000 Jan 15; 95(2):564-8. PubMed ID: 10627463
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  • 11. Reduction of the inhibitory antibody response to human factor VIII in hemophilia A mice by mutagenesis of the A2 domain B-cell epitope.
    Parker ET, Healey JF, Barrow RT, Craddock HN, Lollar P.
    Blood; 2004 Aug 01; 104(3):704-10. PubMed ID: 15073030
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  • 12. Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.
    Scandella D, Gilbert GE, Shima M, Nakai H, Eagleson C, Felch M, Prescott R, Rajalakshmi KJ, Hoyer LW, Saenko E.
    Blood; 1995 Sep 01; 86(5):1811-9. PubMed ID: 7544643
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  • 13. Mild hemophilia A patient with novel Pro1809Leu mutation develops an anti-C2 antibody inhibiting allogeneic but not autologous factor VIII activity.
    Yada K, Nogami K, Takeyama M, Ogiwara K, Wakabayashi H, Shima M.
    J Thromb Haemost; 2015 Oct 01; 13(10):1843-53. PubMed ID: 26278069
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  • 17. The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfaces.
    Brison CM, Mullen SM, Wuerth ME, Podolsky K, Cook M, Herman JA, Walter JD, Meeks SL, Spiegel PC.
    PLoS One; 2015 Oct 01; 10(3):e0122447. PubMed ID: 25775247
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  • 18. Different factor VIII neutralizing effects on anti-factor VIII inhibitor antibodies associated with epitope specificity and von Willebrand factor.
    Yada K, Nogami K, Shima M.
    Br J Haematol; 2013 Oct 01; 163(1):104-11. PubMed ID: 23889549
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  • 20. A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor.
    Jacquemin M, Benhida A, Peerlinck K, Desqueper B, Vander Elst L, Lavend'homme R, d'Oiron R, Schwaab R, Bakkus M, Thielemans K, Gilles JG, Vermylen J, Saint-Remy JM.
    Blood; 2000 Jan 01; 95(1):156-63. PubMed ID: 10607698
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