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Journal Abstract Search
214 related items for PubMed ID: 9816165
1. Thymidylate synthase inhibitors. Touroutoglou N, Pazdur R. Clin Cancer Res; 1996 Feb; 2(2):227-43. PubMed ID: 9816165 [Abstract] [Full Text] [Related]
7. In vitro uptake, anabolism, and cellular retention of 1843U89 and other benzoquinazoline inhibitors of thymidylate synthase. Hanlon MH, Ferone R. Cancer Res; 1996 Jul 15; 56(14):3301-6. PubMed ID: 8764125 [Abstract] [Full Text] [Related]
8. Quinazoline thymidylate synthase inhibitors: methods for assessing the contribution of polyglutamation to their in vitro activity. Jackman AL, Kimbell R, Brown M, Brunton L, Boyle FT. Anticancer Drug Des; 1995 Oct 15; 10(7):555-72. PubMed ID: 7495479 [Abstract] [Full Text] [Related]
10. Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase. Jones TR, Varney MD, Webber SE, Lewis KK, Marzoni GP, Palmer CL, Kathardekar V, Welsh KM, Webber S, Matthews DA, Appelt K, Smith WW, Janson CA, Villafranca JE, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Moomaw EW, Bartlett CA, Morse CA. J Med Chem; 1996 Feb 16; 39(4):904-17. PubMed ID: 8632414 [Abstract] [Full Text] [Related]
11. Quinazoline-based thymidylate synthase inhibitors: relationship between structural modifications and polyglutamation. Jackman AL, Kimbell R, Brown M, Brunton L, Bisset GM, Bavetsias V, Marsham P, Hughes LR, Boyle FT. Anticancer Drug Des; 1995 Oct 16; 10(7):573-89. PubMed ID: 7495480 [Abstract] [Full Text] [Related]
14. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. van Triest B, Pinedo HM, van Hensbergen Y, Smid K, Telleman F, Schoenmakers PS, van der Wilt CL, van Laar JA, Noordhuis P, Jansen G, Peters GJ. Clin Cancer Res; 1999 Mar 16; 5(3):643-54. PubMed ID: 10100718 [Abstract] [Full Text] [Related]
15. Initiatives with platinum- and quinazoline-based antitumor molecules--Fourteenth Bruce F. Cain Memorial Award Lecture. Harrap KR. Cancer Res; 1995 Jul 01; 55(13):2761-8. PubMed ID: 7796401 [Abstract] [Full Text] [Related]
17. Tomudex (ZD1694): from concept to care, a programme in rational drug discovery. Jackman AL, Boyle FT, Harrap KR. Invest New Drugs; 1996 Jul 01; 14(3):305-16. PubMed ID: 8958186 [Abstract] [Full Text] [Related]
18. A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies. Schwartz G, Johnson TR, Goetz A, Burris H, Smetzer L, Lampkin T, Sailstad J, Hohneker JA, Von Hoff DD, Rowinsky EK. Clin Cancer Res; 2001 Jul 01; 7(7):1901-11. PubMed ID: 11448903 [Abstract] [Full Text] [Related]