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Journal Abstract Search

249 related items for PubMed ID: 9819201

  • 1. Three-dimensional structure of AmpC beta-lactamase from Escherichia coli bound to a transition-state analogue: possible implications for the oxyanion hypothesis and for inhibitor design.
    Usher KC, Blaszczak LC, Weston GS, Shoichet BK, Remington SJ.
    Biochemistry; 1998 Nov 17; 37(46):16082-92. PubMed ID: 9819201
    [Abstract] [Full Text] [Related]

  • 2. Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase.
    Weston GS, Blázquez J, Baquero F, Shoichet BK.
    J Med Chem; 1998 Nov 05; 41(23):4577-86. PubMed ID: 9804697
    [Abstract] [Full Text] [Related]

  • 3. Nanomolar inhibitors of AmpC beta-lactamase.
    Morandi F, Caselli E, Morandi S, Focia PJ, Blázquez J, Shoichet BK, Prati F.
    J Am Chem Soc; 2003 Jan 22; 125(3):685-95. PubMed ID: 12526668
    [Abstract] [Full Text] [Related]

  • 4. Thermodynamic cycle analysis and inhibitor design against beta-lactamase.
    Roth TA, Minasov G, Morandi S, Prati F, Shoichet BK.
    Biochemistry; 2003 Dec 16; 42(49):14483-91. PubMed ID: 14661960
    [Abstract] [Full Text] [Related]

  • 5. Functional analyses of AmpC beta-lactamase through differential stability.
    Beadle BM, McGovern SL, Patera A, Shoichet BK.
    Protein Sci; 1999 Sep 16; 8(9):1816-24. PubMed ID: 10493583
    [Abstract] [Full Text] [Related]

  • 6. Thermodynamic evaluation of a covalently bonded transition state analogue inhibitor: inhibition of beta-lactamases by phosphonates.
    Nagarajan R, Pratt RF.
    Biochemistry; 2004 Aug 03; 43(30):9664-73. PubMed ID: 15274621
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate.
    Nukaga M, Abe T, Venkatesan AM, Mansour TS, Bonomo RA, Knox JR.
    Biochemistry; 2003 Nov 18; 42(45):13152-9. PubMed ID: 14609325
    [Abstract] [Full Text] [Related]

  • 8. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
    Sun T, Bethel CR, Bonomo RA, Knox JR.
    Biochemistry; 2004 Nov 09; 43(44):14111-7. PubMed ID: 15518561
    [Abstract] [Full Text] [Related]

  • 9. The complexed structure and antimicrobial activity of a non-beta-lactam inhibitor of AmpC beta-lactamase.
    Powers RA, Blázquez J, Weston GS, Morosini MI, Baquero F, Shoichet BK.
    Protein Sci; 1999 Nov 09; 8(11):2330-7. PubMed ID: 10595535
    [Abstract] [Full Text] [Related]

  • 10. Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state kinetics.
    Kumar S, Adediran SA, Nukaga M, Pratt RF.
    Biochemistry; 2004 Mar 09; 43(9):2664-72. PubMed ID: 14992604
    [Abstract] [Full Text] [Related]

  • 11. Noncovalent interaction energies in covalent complexes: TEM-1 beta-lactamase and beta-lactams.
    Wang X, Minasov G, Shoichet BK.
    Proteins; 2002 Apr 01; 47(1):86-96. PubMed ID: 11870868
    [Abstract] [Full Text] [Related]

  • 12. Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases.
    Maveyraud L, Pratt RF, Samama JP.
    Biochemistry; 1998 Feb 24; 37(8):2622-8. PubMed ID: 9485412
    [Abstract] [Full Text] [Related]

  • 13. Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.
    Buzzoni V, Blazquez J, Ferrari S, Calò S, Venturelli A, Costi MP.
    Bioorg Med Chem Lett; 2004 Aug 02; 14(15):3979-83. PubMed ID: 15225711
    [Abstract] [Full Text] [Related]

  • 14. Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis.
    Chen CC, Rahil J, Pratt RF, Herzberg O.
    J Mol Biol; 1993 Nov 05; 234(1):165-78. PubMed ID: 8230196
    [Abstract] [Full Text] [Related]

  • 15. Structural aspects for evolution of beta-lactamases from penicillin-binding proteins.
    Meroueh SO, Minasov G, Lee W, Shoichet BK, Mobashery S.
    J Am Chem Soc; 2003 Aug 13; 125(32):9612-8. PubMed ID: 12904027
    [Abstract] [Full Text] [Related]

  • 16. Structure-based approach for binding site identification on AmpC beta-lactamase.
    Powers RA, Shoichet BK.
    J Med Chem; 2002 Jul 18; 45(15):3222-34. PubMed ID: 12109906
    [Abstract] [Full Text] [Related]

  • 17. Crystal structure of a complex between the Actinomadura R39 DD-peptidase and a peptidoglycan-mimetic boronate inhibitor: interpretation of a transition state analogue in terms of catalytic mechanism.
    Dzhekieva L, Rocaboy M, Kerff F, Charlier P, Sauvage E, Pratt RF.
    Biochemistry; 2010 Aug 03; 49(30):6411-9. PubMed ID: 20608745
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.
    Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR.
    J Med Chem; 2004 Dec 16; 47(26):6556-68. PubMed ID: 15588091
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion.
    Ibuka AS, Ishii Y, Galleni M, Ishiguro M, Yamaguchi K, Frère JM, Matsuzawa H, Sakai H.
    Biochemistry; 2003 Sep 16; 42(36):10634-43. PubMed ID: 12962487
    [Abstract] [Full Text] [Related]

  • 20. The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state.
    Silvaggi NR, Anderson JW, Brinsmade SR, Pratt RF, Kelly JA.
    Biochemistry; 2003 Feb 11; 42(5):1199-208. PubMed ID: 12564922
    [Abstract] [Full Text] [Related]

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