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Journal Abstract Search

96 related items for PubMed ID: 9829757

  • 1. Pharmacokinetics of O6-benzylguanine and its active metabolite 8-oxo-O6-benzylguanine in plasma and cerebrospinal fluid after intrathecal administration of O6-benzylguanine in the nonhuman primate.
    Berg SL, Murry DJ, McCully CL, Godwin K, Balis FM.
    Clin Cancer Res; 1998 Nov; 4(11):2891-4. PubMed ID: 9829757
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  • 2. Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate.
    Berg SL, Gerson SL, Godwin K, Cole DE, Liu L, Balis FM.
    Cancer Res; 1995 Oct 15; 55(20):4606-10. PubMed ID: 7553637
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  • 3. Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.
    Long L, Berg SL, Roy SK, McCully CL, Song-Yoo HW, Moschel RC, Balis FM, Dolan ME.
    Clin Cancer Res; 2000 Sep 15; 6(9):3662-9. PubMed ID: 10999759
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  • 4. Simultaneous determination of O6-benzylguanine and 8-oxo-O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography.
    Stefan TL, Ingalls ST, Minkler PE, Willson JK, Gerson SL, Spiro TP, Hoppel CL.
    J Chromatogr B Biomed Sci Appl; 1997 Dec 19; 704(1-2):289-98. PubMed ID: 9518162
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  • 5. Pharmacokinetics of O6-benzylguanine in rats and its metabolism by rat liver microsomes.
    Roy SK, Gupta E, Dolan ME.
    Drug Metab Dispos; 1995 Dec 19; 23(12):1394-9. PubMed ID: 8689950
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  • 6. Pharmacokinetics of O6-benzylguanine (NSC637037) and its metabolite, 8-oxo-O6-benzylguanine.
    Tserng KY, Ingalls ST, Boczko EM, Spiro TP, Li X, Majka S, Gerson SL, Willson JK, Hoppel CL.
    J Clin Pharmacol; 2003 Aug 19; 43(8):881-93. PubMed ID: 12953345
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  • 7. Pharmacokinetics of O(6)-benzylguanine in pediatric patients with central nervous system tumors: a pediatric oncology group study.
    Neville K, Blaney S, Bernstein M, Thompson P, Adams D, Aleksic A, Berg S.
    Clin Cancer Res; 2004 Aug 01; 10(15):5072-5. PubMed ID: 15297409
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  • 9. O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings.
    Dolan ME, Roy SK, Fasanmade AA, Paras PR, Schilsky RL, Ratain MJ.
    J Clin Oncol; 1998 May 01; 16(5):1803-10. PubMed ID: 9586894
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  • 15. Cerebrospinal fluid pharmacokinetics and toxicology of intraventricular and intrathecal arabinosyl-5-azacytosine (fazarabine, NSC 281272) in the nonhuman primate.
    Heideman RL, McCully C, Balis FM, Poplack DG.
    Invest New Drugs; 1993 May 01; 11(2-3):135-40. PubMed ID: 7505267
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  • 16. O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair.
    Spiro TP, Gerson SL, Liu L, Majka S, Haaga J, Hoppel CL, Ingalls ST, Pluda JM, Willson JK.
    Cancer Res; 1999 May 15; 59(10):2402-10. PubMed ID: 10344750
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  • 17. Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
    Mitchell RB, Moschel RC, Dolan ME.
    Cancer Res; 1992 Mar 01; 52(5):1171-5. PubMed ID: 1737376
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