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Journal Abstract Search

335 related items for PubMed ID: 9836602

  • 1. Oxyanion-mediated inhibition of serine proteases.
    Presnell SR, Patil GS, Mura C, Jude KM, Conley JM, Bertrand JA, Kam CM, Powers JC, Williams LD.
    Biochemistry; 1998 Dec 01; 37(48):17068-81. PubMed ID: 9836602
    [Abstract] [Full Text] [Related]

  • 2. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W.
    J Mol Biol; 2001 Apr 13; 307(5):1451-86. PubMed ID: 11292354
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models.
    Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD.
    Biochemistry; 1996 Mar 12; 35(10):3147-55. PubMed ID: 8605148
    [Abstract] [Full Text] [Related]

  • 4. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
    Nardini M, Pesce A, Rizzi M, Casale E, Ferraccioli R, Balliano G, Milla P, Ascenzi P, Bolognesi M.
    J Mol Biol; 1996 May 24; 258(5):851-9. PubMed ID: 8637015
    [Abstract] [Full Text] [Related]

  • 5. Recruiting Zn2+ to mediate potent, specific inhibition of serine proteases.
    Katz BA, Luong C.
    J Mol Biol; 1999 Sep 24; 292(3):669-84. PubMed ID: 10497030
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of bovine beta-trypsin, human alpha-thrombin and porcine pancreatic beta-kallikrein-B by benzamidine and its bis-, tris- and tetra-derivatives: thermodynamic and molecular modeling study.
    Menegatti E, Ferroni R, Nastruzzi C, Bortolotti F, Scalia S, Amiconi G, Bolognesi M, Coletta M, Onesti S, Fruttero R.
    Farmaco; 1991 Nov 24; 46(11):1297-310. PubMed ID: 1811616
    [Abstract] [Full Text] [Related]

  • 7. Crystal structure of recombinant human tissue kallikrein at 2.0 A resolution.
    Katz BA, Liu B, Barnes M, Springman EB.
    Protein Sci; 1998 Apr 24; 7(4):875-85. PubMed ID: 9568894
    [Abstract] [Full Text] [Related]

  • 8. Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
    Krishnan R, Zhang E, Hakansson K, Arni RK, Tulinsky A, Lim-Wilby MS, Levy OE, Semple JE, Brunck TK.
    Biochemistry; 1998 Sep 01; 37(35):12094-103. PubMed ID: 9724521
    [Abstract] [Full Text] [Related]

  • 9. Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.
    Shia S, Stamos J, Kirchhofer D, Fan B, Wu J, Corpuz RT, Santell L, Lazarus RA, Eigenbrot C.
    J Mol Biol; 2005 Mar 11; 346(5):1335-49. PubMed ID: 15713485
    [Abstract] [Full Text] [Related]

  • 10. 13C- and 1H-NMR studies of oxyanion and tetrahedral intermediate stabilization by the serine proteinases: optimizing inhibitor warhead specificity and potency by studying the inhibition of the serine proteinases by peptide-derived chloromethane and glyoxal inhibitors.
    Malthouse JP.
    Biochem Soc Trans; 2007 Jun 11; 35(Pt 3):566-70. PubMed ID: 17511653
    [Abstract] [Full Text] [Related]

  • 11. Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
    Gillmor SA, Takeuchi T, Yang SQ, Craik CS, Fletterick RJ.
    J Mol Biol; 2000 Jun 16; 299(4):993-1003. PubMed ID: 10843853
    [Abstract] [Full Text] [Related]

  • 12. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
    Malikayil JA, Burkhart JP, Schreuder HA, Broersma RJ, Tardif C, Kutcher LW, Mehdi S, Schatzman GL, Neises B, Peet NP.
    Biochemistry; 1997 Feb 04; 36(5):1034-40. PubMed ID: 9033393
    [Abstract] [Full Text] [Related]

  • 13. A novel approach to serine protease inhibition: kinetic characterization of inhibitors whose potencies and selectivities are dramatically enhanced by Zinc(II).
    Janc JW, Clark JM, Warne RL, Elrod KC, Katz BA, Moore WR.
    Biochemistry; 2000 Apr 25; 39(16):4792-800. PubMed ID: 10769136
    [Abstract] [Full Text] [Related]

  • 14. Predicted three-dimensional structural models of venom serine protease inhibitors and their interactions with trypsin and chymotrypsin.
    Azim MK, Grossmann JG, Zaidi ZH.
    J Nat Toxins; 1999 Oct 25; 8(3):363-84. PubMed ID: 10591040
    [Abstract] [Full Text] [Related]

  • 15. Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator.
    Song HK, Suh SW.
    J Mol Biol; 1998 Jan 16; 275(2):347-63. PubMed ID: 9466914
    [Abstract] [Full Text] [Related]

  • 16. Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.
    Costanzo MJ, Yabut SC, Almond HR, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, Maryanoff BE.
    J Med Chem; 2003 Aug 28; 46(18):3865-76. PubMed ID: 12930148
    [Abstract] [Full Text] [Related]

  • 17. Structure-function relationship of serine protease-protein inhibitor interaction.
    Otlewski J, Jaskólski M, Buczek O, Cierpicki T, Czapińska H, Krowarsch D, Smalas AO, Stachowiak D, Szpineta A, Dadlez M.
    Acta Biochim Pol; 2001 Aug 28; 48(2):419-28. PubMed ID: 11732612
    [Abstract] [Full Text] [Related]

  • 18. Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.
    Weir MP, Bethell SS, Cleasby A, Campbell CJ, Dennis RJ, Dix CJ, Finch H, Jhoti H, Mooney CJ, Patel S, Tang CM, Ward M, Wonacott AJ, Wharton CW.
    Biochemistry; 1998 May 12; 37(19):6645-57. PubMed ID: 9578548
    [Abstract] [Full Text] [Related]

  • 19. Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions.
    Di Fenza A, Heine A, Koert U, Klebe G.
    ChemMedChem; 2007 Mar 12; 2(3):297-308. PubMed ID: 17191291
    [Abstract] [Full Text] [Related]

  • 20. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I.
    Bateman KS, Huang K, Anderson S, Lu W, Qasim MA, Laskowski M, James MN.
    J Mol Biol; 2001 Jan 26; 305(4):839-49. PubMed ID: 11162096
    [Abstract] [Full Text] [Related]

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