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Journal Abstract Search

108 related items for PubMed ID: 985569

  • 1. The metabolism of the anti-tumour agent 5-(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954).
    Jarman M, Melzack DH, Ross WC.
    Biochem Pharmacol; 1976 Nov 15; 25(22):2475-8. PubMed ID: 985569
    [No Abstract] [Full Text] [Related]

  • 2. The metabolism of the anti-tumour agent 1(1-aziridinyl)- 2,4-dinitrobenzene (CB 1837).
    Connors TA, Hickman JA, Jarman M, Melzack DH, Ross WC.
    Biochem Pharmacol; 1975 Sep 15; 24(18):1665-70. PubMed ID: 1191326
    [No Abstract] [Full Text] [Related]

  • 3. A new cytotoxic, DNA interstrand crosslinking agent, 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide, is formed from 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by a nitroreductase enzyme in Walker carcinoma cells.
    Knox RJ, Friedlos F, Jarman M, Roberts JJ.
    Biochem Pharmacol; 1988 Dec 15; 37(24):4661-9. PubMed ID: 3202902
    [Abstract] [Full Text] [Related]

  • 4. CB 1954 (2,4-dinitro-5-aziridinyl benzamide) becomes a DNA interstrand crosslinking agent in Walker tumour cells.
    Roberts JJ, Friedlos F, Knox RJ.
    Biochem Biophys Res Commun; 1986 Nov 14; 140(3):1073-8. PubMed ID: 3778483
    [Abstract] [Full Text] [Related]

  • 5. Selective inhibition of ribonucleotide reductase by the monofunctional alkylating agent 5(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954).
    Tisdale MJ, Habberfield AD.
    Biochem Pharmacol; 1980 Oct 15; 29(20):2845-53. PubMed ID: 7002161
    [No Abstract] [Full Text] [Related]

  • 6. The nitroreductase enzyme in Walker cells that activates 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) to 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide is a form of NAD(P)H dehydrogenase (quinone) (EC 1.6.99.2).
    Knox RJ, Boland MP, Friedlos F, Coles B, Southan C, Roberts JJ.
    Biochem Pharmacol; 1988 Dec 15; 37(24):4671-7. PubMed ID: 3144286
    [Abstract] [Full Text] [Related]

  • 7. [Metabolism of the antineoplastic agent N-pyrimidly-2N1, N2-di-(ethylene)-triamide phosphate (fosfemid)].
    Safonova TS, Linberg LF, Presnova ZhF, Kuriatov NS, Chernov VA.
    Dokl Akad Nauk SSSR; 1974 Dec 15; 219(5):1271-2. PubMed ID: 4442341
    [No Abstract] [Full Text] [Related]

  • 8. Studies on the mechanism of action of 5-aziridinyl-2,4-dinitrobenzamide (CB 1954), a selective inhibitor of the Walker tumour.
    Connors TA, Melzack DH.
    Int J Cancer; 1971 Jan 15; 7(1):86-92. PubMed ID: 5546147
    [No Abstract] [Full Text] [Related]

  • 9. Protection against the effects of the antitumour agent CB 1954 by certain imidazoles and related compounds.
    Hickman JA, Melzack DH.
    Biochem Pharmacol; 1975 Nov 01; 24(21):1947-52. PubMed ID: 1212244
    [No Abstract] [Full Text] [Related]

  • 10. Studies on the protection by imidazoles against the cytotoxicity of the antitumour alkylating agents melphalan and CB 1954.
    Hickman JA, Melzack DH.
    Biochem Pharmacol; 1976 Nov 15; 25(22):2489-91. PubMed ID: 985571
    [No Abstract] [Full Text] [Related]

  • 11. Biochemical activation of AZQ [3,6-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone] to its free radical species.
    Gutierrez PL, Friedman RD, Bachur NR.
    Cancer Treat Rep; 1982 Feb 15; 66(2):339-42. PubMed ID: 6275990
    [Abstract] [Full Text] [Related]

  • 12. Cytotoxic activity and fragmentation of aziridines in microsomes.
    Hata Y, Watanabe M, Shiratori O, Takase S.
    Biochem Biophys Res Commun; 1978 Feb 28; 80(4):911-6. PubMed ID: 637875
    [No Abstract] [Full Text] [Related]

  • 13. Response of human tumours 'in vitro' to CB-1954 (5-aziridinyl-2, 4-dinitrobenzamide).
    Bhat AV, Rao KV, Bapat CV.
    Indian J Cancer; 1977 Jun 28; 14(2):132-5. PubMed ID: 914303
    [No Abstract] [Full Text] [Related]

  • 14. Synthesis and electron spin resonance study of spin-labelled compounds related to tumour-growth inhibitory nitroarylaziridines.
    Dodd NJ, Harcus RG, Preston PN.
    Z Naturforsch C Biosci; 1976 Jun 28; 31(5-6):328-30. PubMed ID: 183409
    [Abstract] [Full Text] [Related]

  • 15. Guanosine 3',5'-monophosphate and the action of alkylating agents.
    Tisdale MJ, Phillips BJ.
    Chem Biol Interact; 1977 Dec 28; 19(3):375-81. PubMed ID: 202413
    [Abstract] [Full Text] [Related]

  • 16. Studies on the reversal of the selective antitumour effect of the aziridinyl derivative CB 1954 by 4-amino-5-imidazolecarboxamide.
    Connors TA, Mandel HG, Melzack DH.
    Int J Cancer; 1972 Jan 15; 9(1):126-32. PubMed ID: 5015661
    [No Abstract] [Full Text] [Related]

  • 17. A new metabolic reaction of diaziridines by rat liver microsomes.
    Hata Y, Watanabe M.
    Biochem Biophys Res Commun; 1982 May 31; 106(2):526-32. PubMed ID: 7104007
    [No Abstract] [Full Text] [Related]

  • 18. Structure activity relationships in a series of anti-neoplastic dinitrophenyl aziridines--protein binding studies.
    Hickman JA.
    Biochem Pharmacol; 1974 Oct 15; 23(20):2833-8. PubMed ID: 4473986
    [No Abstract] [Full Text] [Related]

  • 19. Fragmentation reaction of ylide. 5. A new metabolic reaction of aziridine derivatives.
    Hata Y, Watanabe M, Matsubara T, Touchi A.
    J Am Chem Soc; 1976 Sep 15; 98(19):6033-6. PubMed ID: 965638
    [No Abstract] [Full Text] [Related]

  • 20. The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide).
    Boland MP, Knox RJ, Roberts JJ.
    Biochem Pharmacol; 1976 Sep 15; 41(6-7):867-75. PubMed ID: 1901207
    [Abstract] [Full Text] [Related]

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