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Journal Abstract Search

567 related items for PubMed ID: 9857098

  • 21. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents.
    Gangjee A, Adair OO, Queener SF.
    J Med Chem; 2003 Nov 06; 46(23):5074-82. PubMed ID: 14584957
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  • 22. Further studies on the interaction of nonpolyglutamatable aminopterin analogs with dihydrofolate reductase and the reduced folate carrier as determinants of in vitro antitumor activity.
    Wright JE, Yurasek GK, Chen YN, Rosowsky A.
    Biochem Pharmacol; 2003 May 01; 65(9):1427-33. PubMed ID: 12732354
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  • 23. Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group.
    McGuire JJ, Russell CA, Bolanowska WE, Freitag CM, Jones CS, Kalman TI.
    Cancer Res; 1990 Mar 15; 50(6):1726-31. PubMed ID: 2306727
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  • 24. Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.
    Piper JR, McCaleb GS, Montgomery JA, Kisliuk RL, Gaumont Y, Sirotnak FM.
    J Med Chem; 1986 Jun 15; 29(6):1080-7. PubMed ID: 2423690
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  • 25. Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.
    Robson C, Meek MA, Grunwaldt JD, Lambert PA, Queener SF, Schmidt D, Griffin RJ.
    J Med Chem; 1997 Sep 12; 40(19):3040-8. PubMed ID: 9301666
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  • 27. Synthesis and biological evaluation of N alpha-(4-amino-4-deoxy-10-methylpteroyl)-DL-4,4-difluoroornithine.
    Tsukamoto T, Haile WH, McGuire JJ, Coward JK.
    J Med Chem; 1996 Jun 21; 39(13):2536-40. PubMed ID: 8691451
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  • 29. Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents.
    Gangjee A, Vidwans AP, Vasudevan A, Queener SF, Kisliuk RL, Cody V, Li R, Galitsky N, Luft JR, Pangborn W.
    J Med Chem; 1998 Aug 27; 41(18):3426-34. PubMed ID: 9719595
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  • 31. A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice.
    Sirotnak FM, DeGraw JI, Colwell WT, Piper JR.
    Cancer Chemother Pharmacol; 1998 Aug 27; 42(4):313-8. PubMed ID: 9744777
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  • 32. Synthesis and biological activity of 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid and 5,10-dideaza-5, 6,7,8-tetrahydrofolic acid.
    Borrell JI, Teixidó J, Martínez-Teipel B, Matallana JL, Copete MT, Llimargas A, García E.
    J Med Chem; 1998 Aug 27; 41(18):3539-45. PubMed ID: 9719607
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  • 33. Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
    Rosowsky A, Papoulis AT, Forsch RA, Queener SF.
    J Med Chem; 1999 Mar 25; 42(6):1007-17. PubMed ID: 10090784
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  • 34. Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
    Rosowsky A, Freisheim JH, Moran RG, Solan VC, Bader H, Wright JE, Radike-Smith M.
    J Med Chem; 1986 May 25; 29(5):655-60. PubMed ID: 2871191
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  • 37. Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.
    Norris RE, Adamson PC.
    Cancer Chemother Pharmacol; 2010 May 25; 65(6):1125-30. PubMed ID: 19784838
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