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1052 related items for PubMed ID: 9860831

  • 1. Microsomal cytochrome P450 dependent oxidation of N-hydroxyguanidines, amidoximes, and ketoximes: mechanism of the oxidative cleavage of their C=N(OH) bond with formation of nitrogen oxides.
    Jousserandot A, Boucher JL, Henry Y, Niklaus B, Clement B, Mansuy D.
    Biochemistry; 1998 Dec 08; 37(49):17179-91. PubMed ID: 9860831
    [Abstract] [Full Text] [Related]

  • 2. Oxidation of 9-alkylanthracenes by cytochrome P450 2B1, horseradish peroxidase, and iron tetraphenylporphine/iodosylbenzene systems: anaerobic and aerobic mechanisms.
    Anzenbacher P, Niwa T, Tolbert LM, Sirimanne SR, Guengerich FP.
    Biochemistry; 1996 Feb 27; 35(8):2512-20. PubMed ID: 8611554
    [Abstract] [Full Text] [Related]

  • 3. Oxidation of N-hydroxyguanidines by cytochromes P450 and NO-synthases and formation of nitric oxide.
    Mansuy D, Boucher JL.
    Drug Metab Rev; 2002 Aug 27; 34(3):593-606. PubMed ID: 12214669
    [Abstract] [Full Text] [Related]

  • 4. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Aug 27; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

  • 5. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 27; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

  • 6. Oxidative cleavage of esters and amides to carbonyl products by cytochrome P450.
    Peng HM, Raner GM, Vaz AD, Coon MJ.
    Arch Biochem Biophys; 1995 Apr 20; 318(2):333-9. PubMed ID: 7733661
    [Abstract] [Full Text] [Related]

  • 7. N-hydroxylation of the antiprotozoal drug pentamidine catalyzed by rabbit liver cytochrome P-450 2C3 or human liver microsomes, microsomal retroreduction, and further oxidative transformation of the formed amidoximes. Possible relationship to the biological oxidation of arginine to NG-hydroxyarginine, citrulline, and nitric oxide.
    Clement B, Jung F.
    Drug Metab Dispos; 1994 Apr 20; 22(3):486-97. PubMed ID: 8070328
    [Abstract] [Full Text] [Related]

  • 8. Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s.
    Renaud JP, Boucher JL, Vadon S, Delaforge M, Mansuy D.
    Biochem Biophys Res Commun; 1993 Apr 15; 192(1):53-60. PubMed ID: 7682811
    [Abstract] [Full Text] [Related]

  • 9. Cytochrome P450 responsible for the stereoselective S-oxidation of flosequinan in hepatic microsomes from rats and humans.
    Kashiyama E, Yokoi T, Odomi M, Funae Y, Inoue K, Kamataki T.
    Drug Metab Dispos; 1997 Jun 15; 25(6):716-24. PubMed ID: 9193873
    [Abstract] [Full Text] [Related]

  • 10. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S, Marchick MR, Davis MR, Doss GA, Pohl LR.
    Chem Res Toxicol; 1999 Feb 15; 12(2):214-22. PubMed ID: 10027801
    [Abstract] [Full Text] [Related]

  • 11. Rat liver cytochrome P450 metabolism of N-acetylbenzidine and N,N'-diacetylbenzidine.
    Lakshmi VM, Zenser TV, Davis BB.
    Drug Metab Dispos; 1997 Apr 15; 25(4):481-8. PubMed ID: 9107548
    [Abstract] [Full Text] [Related]

  • 12. Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity.
    Moali C, Boucher JL, Renodon-Corniere A, Stuehr DJ, Mansuy D.
    Chem Res Toxicol; 2001 Feb 15; 14(2):202-10. PubMed ID: 11258969
    [Abstract] [Full Text] [Related]

  • 13. Alternative nitric oxide-producing substrates for NO synthases.
    Mansuy D, Boucher JL.
    Free Radic Biol Med; 2004 Oct 15; 37(8):1105-21. PubMed ID: 15451052
    [Abstract] [Full Text] [Related]

  • 14. Cytochrome P-450-dependent formation of reactive oxygen radicals: isozyme-specific inhibition of P-450-mediated reduction of oxygen and carbon tetrachloride.
    Persson JO, Terelius Y, Ingelman-Sundberg M.
    Xenobiotica; 1990 Sep 15; 20(9):887-900. PubMed ID: 2122605
    [Abstract] [Full Text] [Related]

  • 15. Formation of nitric oxide by cytochrome P450-catalyzed oxidation of aromatic amidoximes.
    Andronik-Lion V, Boucher JL, Delaforge M, Henry Y, Mansuy D.
    Biochem Biophys Res Commun; 1992 May 29; 185(1):452-8. PubMed ID: 1599484
    [Abstract] [Full Text] [Related]

  • 16. N,N',N''-triethylenethiophosphoramide (thio-TEPA) oxygenation by constitutive hepatic P450 enzymes and modulation of drug metabolism and clearance in vivo by P450-inducing agents.
    Ng SF, Waxman DJ.
    Cancer Res; 1991 May 01; 51(9):2340-5. PubMed ID: 1707751
    [Abstract] [Full Text] [Related]

  • 17. Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems.
    Caro AA, Cederbaum AI, Stoyanovsky DA.
    Nitric Oxide; 2001 Aug 01; 5(4):413-24. PubMed ID: 11485379
    [Abstract] [Full Text] [Related]

  • 18. Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-alpha-(2-methylazo)-p-toluamide, the azo derivative of procarbazine.
    Prough RA, Brown MI, Dannan GA, Guengerich FP.
    Cancer Res; 1984 Feb 01; 44(2):543-8. PubMed ID: 6692359
    [Abstract] [Full Text] [Related]

  • 19. Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
    Ng SF, Waxman DJ.
    Cancer Res; 1990 Feb 01; 50(3):464-71. PubMed ID: 2105156
    [Abstract] [Full Text] [Related]

  • 20. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP, Yan J, Fu PP, Chou MW.
    Toxicol Lett; 2005 Mar 15; 155(3):411-20. PubMed ID: 15649625
    [Abstract] [Full Text] [Related]

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