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Journal Abstract Search

95 related items for PubMed ID: 9868169

  • 1. Clavaric acid: a triterpenoid inhibitor of farnesyl-protein transferase from Clavariadelphus truncatus.
    Jayasuriya H, Silverman KC, Zink DL, Jenkins RG, Sanchez M, Pelaez F, Vilella D, Lingham RB, Singh SB.
    J Nat Prod; 1998 Dec; 61(12):1568-70. PubMed ID: 9868169
    [Abstract] [Full Text] [Related]

  • 2. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
    Lingham RB, Silverman KC, Jayasuriya H, Kim BM, Amo SE, Wilson FR, Rew DJ, Schaber MD, Bergstrom JD, Koblan KS, Graham SL, Kohl NE, Gibbs JB, Singh SB.
    J Med Chem; 1998 Nov 05; 41(23):4492-501. PubMed ID: 9804689
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  • 3. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
    Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
    Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396
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  • 4. Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.
    Omer CA, Chen Z, Diehl RE, Conner MW, Chen HY, Trumbauer ME, Gopal-Truter S, Seeburger G, Bhimnathwala H, Abrams MT, Davide JP, Ellis MS, Gibbs JB, Greenberg I, Koblan KS, Kral AM, Liu D, Lobell RB, Miller PJ, Mosser SD, O'Neill TJ, Rands E, Schaber MD, Senderak ET, Oliff A, Kohl NE.
    Cancer Res; 2000 May 15; 60(10):2680-8. PubMed ID: 10825141
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  • 5. Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.
    Silverman KC, Jayasuriya H, Cascales C, Vilella D, Bills GF, Jenkins RG, Singh SB, Lingham RB.
    Biochem Biophys Res Commun; 1997 Mar 17; 232(2):478-81. PubMed ID: 9125205
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  • 8. Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.
    Anthony NJ, Gomez RP, Schaber MD, Mosser SD, Hamilton KA, O'Neil TJ, Koblan KS, Graham SL, Hartman GD, Shah D, Rands E, Kohl NE, Gibbs JB, Oliff AI.
    J Med Chem; 1999 Aug 26; 42(17):3356-68. PubMed ID: 10464022
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  • 9. Biochemical and biological analyses of farnesyl-protein transferase inhibitors.
    Kohl NE, Koblan KS, Omer CA, Oliff A, Gibbs JB.
    Methods Mol Biol; 1998 Aug 26; 84():283-91. PubMed ID: 9666457
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  • 11. Farnesyl protein transferase inhibitory components of Polygonum multiflorum.
    Kwon BM, Kim SH, Baek NI, Lee SI, Kim EJ, Yang JH, Chae BS, Lee JH, Park HW, Park JS, Kim DK.
    Arch Pharm Res; 2009 Apr 26; 32(4):495-9. PubMed ID: 19407965
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  • 12. Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis.
    Singh SB, Zink DL, Williams M, Polishook JD, Sanchez M, Silverman KC, Lingham RB.
    Bioorg Med Chem Lett; 1998 Aug 18; 8(16):2071-6. PubMed ID: 9873488
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  • 13. A combined treatment of HeLa cells with the farnesyl protein transferase inhibitor L-744,832 and cisplatin significantly increases the therapeutic effect as compared to cisplatin monotherapy.
    Wesierska-Gadek J, Kramer MP, Schmid G.
    J Cell Biochem; 2008 May 01; 104(1):189-201. PubMed ID: 18022825
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  • 14. Current progress on farnesyl protein transferase inhibitors.
    Singh SB, Lingham RB.
    Curr Opin Drug Discov Devel; 2002 Mar 01; 5(2):225-44. PubMed ID: 11926129
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  • 15. [Three dimensional quantitative structure-activity relationship of a series of benzocylohepatpyridine farnesyltransferase inhibitors].
    Wan SB, Yi X, Guo ZR.
    Yao Xue Xue Bao; 2002 Apr 01; 37(4):257-62. PubMed ID: 12579819
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  • 16. A squalene epoxidase is involved in biosynthesis of both the antitumor compound clavaric acid and sterols in the basidiomycete H. sublateritium.
    Godio RP, Fouces R, Martín JF.
    Chem Biol; 2007 Dec 01; 14(12):1334-46. PubMed ID: 18096502
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