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433 related items for PubMed ID: 9873017

  • 1. Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation.
    Han Y, Weinman S, Boldogh I, Walker RK, Brasier AR.
    J Biol Chem; 1999 Jan 08; 274(2):787-94. PubMed ID: 9873017
    [Abstract] [Full Text] [Related]

  • 2. Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation.
    Kim HT, Qiang W, Wong PK, Stoica G.
    J Neurovirol; 2001 Oct 08; 7(5):466-75. PubMed ID: 11582519
    [Abstract] [Full Text] [Related]

  • 3. Transient nuclear factor kappaB (NF-kappaB) activation stimulated by interleukin-1beta may be partly dependent on proteasome activity, but not phosphorylation and ubiquitination of the IkappaBalpha molecule, in C6 glioma cells. Regulation of NF-kappaB linked to chemokine production.
    Uehara T, Matsuno J, Kaneko M, Nishiya T, Fujimuro M, Yokosawa H, Nomura Y.
    J Biol Chem; 1999 May 28; 274(22):15875-82. PubMed ID: 10336492
    [Abstract] [Full Text] [Related]

  • 4. The major component of IkappaBalpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells.
    Jamaluddin M, Casola A, Garofalo RP, Han Y, Elliott T, Ogra PL, Brasier AR.
    J Virol; 1998 Jun 28; 72(6):4849-57. PubMed ID: 9573251
    [Abstract] [Full Text] [Related]

  • 5. Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha.
    Mukhopadhyay A, Manna SK, Aggarwal BB.
    J Biol Chem; 2000 Mar 24; 275(12):8549-55. PubMed ID: 10722693
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of IkappaB-alpha and IkappaB-beta proteolysis by calpain inhibitor I blocks nitric oxide synthesis.
    Milligan SA, Owens MW, Grisham MB.
    Arch Biochem Biophys; 1996 Nov 15; 335(2):388-95. PubMed ID: 8914937
    [Abstract] [Full Text] [Related]

  • 7. Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo.
    Roff M, Thompson J, Rodriguez MS, Jacque JM, Baleux F, Arenzana-Seisdedos F, Hay RT.
    J Biol Chem; 1996 Mar 29; 271(13):7844-50. PubMed ID: 8631829
    [Abstract] [Full Text] [Related]

  • 8. Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
    Alkalay I, Yaron A, Hatzubai A, Orian A, Ciechanover A, Ben-Neriah Y.
    Proc Natl Acad Sci U S A; 1995 Nov 07; 92(23):10599-603. PubMed ID: 7479848
    [Abstract] [Full Text] [Related]

  • 9. Ubiquitin/proteasome-dependent degradation of D-type cyclins is linked to tumor necrosis factor-induced cell cycle arrest.
    Hu X, Bryington M, Fisher AB, Liang X, Zhang X, Cui D, Datta I, Zuckerman KS.
    J Biol Chem; 2002 May 10; 277(19):16528-37. PubMed ID: 11864973
    [Abstract] [Full Text] [Related]

  • 10. A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells.
    Shumway SD, Miyamoto S.
    Biochem J; 2004 May 15; 380(Pt 1):173-80. PubMed ID: 14763901
    [Abstract] [Full Text] [Related]

  • 11. Cleavage of IκBα by calpain induces myocardial NF-κB activation, TNF-α expression, and cardiac dysfunction in septic mice.
    Li X, Luo R, Chen R, Song L, Zhang S, Hua W, Chen H.
    Am J Physiol Heart Circ Physiol; 2014 Mar 15; 306(6):H833-43. PubMed ID: 24441549
    [Abstract] [Full Text] [Related]

  • 12. Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB.
    Whitehouse AS, Tisdale MJ.
    Br J Cancer; 2003 Sep 15; 89(6):1116-22. PubMed ID: 12966435
    [Abstract] [Full Text] [Related]

  • 13. SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
    Desterro JM, Rodriguez MS, Hay RT.
    Mol Cell; 1998 Aug 15; 2(2):233-9. PubMed ID: 9734360
    [Abstract] [Full Text] [Related]

  • 14. Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors.
    Sakai T, Kambe F, Mitsuyama H, Ishiguro N, Kurokouchi K, Takigawa M, Iwata H, Seo H.
    J Bone Miner Res; 2001 Jul 15; 16(7):1272-80. PubMed ID: 11450703
    [Abstract] [Full Text] [Related]

  • 15. Inducible NF-kappaB activation is permitted by simultaneous degradation of nuclear IkappaBalpha.
    Renard P, Percherancier Y, Kroll M, Thomas D, Virelizier JL, Arenzana-Seisdedos F, Bachelerie F.
    J Biol Chem; 2000 May 19; 275(20):15193-9. PubMed ID: 10809754
    [Abstract] [Full Text] [Related]

  • 16. Mechanism for biphasic rel A. NF-kappaB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes.
    Han Y, Brasier AR.
    J Biol Chem; 1997 Apr 11; 272(15):9825-32. PubMed ID: 9092517
    [Abstract] [Full Text] [Related]

  • 17. p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα.
    Schweitzer K, Pralow A, Naumann M.
    J Cell Mol Med; 2016 Jan 11; 20(1):58-70. PubMed ID: 26463447
    [Abstract] [Full Text] [Related]

  • 18. Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha.
    de Moissac D, Mustapha S, Greenberg AH, Kirshenbaum LA.
    J Biol Chem; 1998 Sep 11; 273(37):23946-51. PubMed ID: 9727009
    [Abstract] [Full Text] [Related]

  • 19. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms.
    Li N, Karin M.
    Proc Natl Acad Sci U S A; 1998 Oct 27; 95(22):13012-7. PubMed ID: 9789032
    [Abstract] [Full Text] [Related]

  • 20. Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation.
    Roussel RR, Barchowsky A.
    Arch Biochem Biophys; 2000 May 01; 377(1):204-12. PubMed ID: 10775461
    [Abstract] [Full Text] [Related]

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