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Journal Abstract Search

102 related items for PubMed ID: 9873426

  • 1. Synthesis and hypoxia-selective cytotoxicity of a 2-nitroimidazole mustard.
    Lee HH, Palmer BD, Wilson WR, Denny WA.
    Bioorg Med Chem Lett; 1998 Jul 07; 8(13):1741-4. PubMed ID: 9873426
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  • 2. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD, Wilson WR, Anderson RF, Boyd M, Denny WA.
    J Med Chem; 1996 Jun 21; 39(13):2518-28. PubMed ID: 8691449
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  • 3. Hypoxia-selective antitumor agents. 9. Structure-activity relationships for hypoxia-selective cytotoxicity among analogues of 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD, Wilson WR, Atwell GJ, Schultz D, Xu XZ, Denny WA.
    J Med Chem; 1994 Jul 08; 37(14):2175-84. PubMed ID: 8035424
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  • 4. Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
    Palmer BD, Wilson WR, Cliffe S, Denny WA.
    J Med Chem; 1992 Aug 21; 35(17):3214-22. PubMed ID: 1507207
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  • 5. Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.
    Hay MP, Lee HH, Wilson WR, Roberts PB, Denny WA.
    J Med Chem; 1995 May 26; 38(11):1928-41. PubMed ID: 7783125
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: a new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers.
    Hay MP, Wilson WR, Moselen JW, Palmer BD, Denny WA.
    J Med Chem; 1994 Feb 04; 37(3):381-91. PubMed ID: 8308864
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  • 12. Nitroimidazole-based "extruded mustards' designed as reductively activated hypoxia-selective cytotoxins.
    Hay MP, Denny WA, Wilson WR.
    Anticancer Drug Des; 1996 Jul 04; 11(5):383-402. PubMed ID: 8765531
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  • 14. Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase.
    Anlezark GM, Melton RG, Sherwood RF, Wilson WR, Denny WA, Palmer BD, Knox RJ, Friedlos F, Williams A.
    Biochem Pharmacol; 1995 Aug 25; 50(5):609-18. PubMed ID: 7669063
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  • 15. Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2,4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862: distinct mechanisms of bioreductive activation.
    Helsby NA, Wheeler SJ, Pruijn FB, Palmer BD, Yang S, Denny WA, Wilson WR.
    Chem Res Toxicol; 2003 Apr 25; 16(4):469-78. PubMed ID: 12703963
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  • 16. Synthesis and preliminary characterization of a novel substrate for gamma-glutamyl transferase. A potential anti-hepatoma drug.
    Smith GD, Chakravarty PK, Connors TA, Peters TJ.
    Biochem Pharmacol; 1984 Feb 15; 33(4):527-9. PubMed ID: 6142715
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  • 17. Nitroimidazole-based bioreductive compounds bearing a quinazoline or a naphthyridine chromophore.
    Papadopoulou MV, Bloomer WD.
    Anticancer Drugs; 2009 Jul 15; 20(6):493-502. PubMed ID: 19430289
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  • 19. Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.
    Lee HH, Wilson WR, Ferry DM, van Zijl P, Pullen SM, Denny WA.
    J Med Chem; 1996 Jun 21; 39(13):2508-17. PubMed ID: 8691448
    [Abstract] [Full Text] [Related]

  • 20. [In vitro studies of the antitumor effect of melphalan and analogous aniline mustard derivatives].
    Laske R, Krischke W, Loos U.
    Arch Pharm (Weinheim); 1989 Sep 21; 322(9):517-21. PubMed ID: 2610585
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