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305 related items for PubMed ID: 9874570

  • 1. Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.
    MacDonald G, Shi L, Vande Velde C, Lieberman J, Greenberg AH.
    J Exp Med; 1999 Jan 04; 189(1):131-44. PubMed ID: 9874570
    [Abstract] [Full Text] [Related]

  • 2. Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent.
    Heibein JA, Barry M, Motyka B, Bleackley RC.
    J Immunol; 1999 Nov 01; 163(9):4683-93. PubMed ID: 10528165
    [Abstract] [Full Text] [Related]

  • 3. Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.
    Estella E, McKenzie MD, Catterall T, Sutton VR, Bird PI, Trapani JA, Kay TW, Thomas HE.
    Diabetes; 2006 Aug 01; 55(8):2212-9. PubMed ID: 16873683
    [Abstract] [Full Text] [Related]

  • 4. Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.
    Waterhouse NJ, Sedelies KA, Sutton VR, Pinkoski MJ, Thia KY, Johnstone R, Bird PI, Green DR, Trapani JA.
    Cell Death Differ; 2006 Apr 01; 13(4):607-18. PubMed ID: 16167065
    [Abstract] [Full Text] [Related]

  • 5. Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.
    Vermijlen D, Froelich CJ, Luo D, Suarez-Huerta N, Robaye B, Wisse E.
    Cancer Immunol Immunother; 2001 Jun 01; 50(4):212-7. PubMed ID: 11459173
    [Abstract] [Full Text] [Related]

  • 6. Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent.
    Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA, Sutton VR.
    J Biol Chem; 1998 Oct 23; 273(43):27934-8. PubMed ID: 9774406
    [Abstract] [Full Text] [Related]

  • 7. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.
    Li PF, Dietz R, von Harsdorf R.
    EMBO J; 1999 Nov 01; 18(21):6027-36. PubMed ID: 10545114
    [Abstract] [Full Text] [Related]

  • 8. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.
    Bossy-Wetzel E, Newmeyer DD, Green DR.
    EMBO J; 1998 Jan 02; 17(1):37-49. PubMed ID: 9427739
    [Abstract] [Full Text] [Related]

  • 9. Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition.
    Alimonti JB, Shi L, Baijal PK, Greenberg AH.
    J Biol Chem; 2001 Mar 09; 276(10):6974-82. PubMed ID: 11114298
    [Abstract] [Full Text] [Related]

  • 10. Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.
    Shi L, Mai S, Israels S, Browne K, Trapani JA, Greenberg AH.
    J Exp Med; 1997 Mar 03; 185(5):855-66. PubMed ID: 9120391
    [Abstract] [Full Text] [Related]

  • 11. Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway.
    Pinkoski MJ, Waterhouse NJ, Heibein JA, Wolf BB, Kuwana T, Goldstein JC, Newmeyer DD, Bleackley RC, Green DR.
    J Biol Chem; 2001 Apr 13; 276(15):12060-7. PubMed ID: 11278459
    [Abstract] [Full Text] [Related]

  • 12. Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways.
    Saleh AM, Vijayasarathy C, Masoud L, Kumar L, Shahin A, Kambal A.
    Toxicol Appl Pharmacol; 2003 Jul 01; 190(1):47-57. PubMed ID: 12831782
    [Abstract] [Full Text] [Related]

  • 13. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
    Thomas WD, Zhang XD, Franco AV, Nguyen T, Hersey P.
    J Immunol; 2000 Nov 15; 165(10):5612-20. PubMed ID: 11067917
    [Abstract] [Full Text] [Related]

  • 14. Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.
    Browne KA, Blink E, Sutton VR, Froelich CJ, Jans DA, Trapani JA.
    Mol Cell Biol; 1999 Dec 15; 19(12):8604-15. PubMed ID: 10567584
    [Abstract] [Full Text] [Related]

  • 15. The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis.
    Panduri V, Weitzman SA, Chandel N, Kamp DW.
    Am J Respir Cell Mol Biol; 2003 Feb 15; 28(2):241-8. PubMed ID: 12540492
    [Abstract] [Full Text] [Related]

  • 16. Granzyme M mediates a novel form of perforin-dependent cell death.
    Kelly JM, Waterhouse NJ, Cretney E, Browne KA, Ellis S, Trapani JA, Smyth MJ.
    J Biol Chem; 2004 May 21; 279(21):22236-42. PubMed ID: 15028722
    [Abstract] [Full Text] [Related]

  • 17. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
    Kam CM, Hudig D, Powers JC.
    Biochim Biophys Acta; 2000 Mar 07; 1477(1-2):307-23. PubMed ID: 10708866
    [Abstract] [Full Text] [Related]

  • 18. Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.
    Bal-Price A, Brown GC.
    J Neurochem; 2000 Oct 07; 75(4):1455-64. PubMed ID: 10987825
    [Abstract] [Full Text] [Related]

  • 19. Cell death induced by granzyme C.
    Johnson H, Scorrano L, Korsmeyer SJ, Ley TJ.
    Blood; 2003 Apr 15; 101(8):3093-101. PubMed ID: 12515723
    [Abstract] [Full Text] [Related]

  • 20. The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.
    Chen Q, Chai YC, Mazumder S, Jiang C, Macklis RM, Chisolm GM, Almasan A.
    Cell Death Differ; 2003 Mar 15; 10(3):323-34. PubMed ID: 12700632
    [Abstract] [Full Text] [Related]

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