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230 related items for PubMed ID: 9883847

  • 21. Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice.
    Xie J, Chang X, Zhang X, Guo Q.
    Brain Res; 2001 Oct 05; 915(1):1-10. PubMed ID: 11578614
    [Abstract] [Full Text] [Related]

  • 22. Hippocampal seizure resistance and reduced neuronal excitotoxicity in mice lacking the Cav2.3 E/R-type voltage-gated calcium channel.
    Weiergräber M, Henry M, Radhakrishnan K, Hescheler J, Schneider T.
    J Neurophysiol; 2007 May 05; 97(5):3660-9. PubMed ID: 17376845
    [Abstract] [Full Text] [Related]

  • 23. Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: implications for seizure susceptibility.
    Balosso S, Ravizza T, Pierucci M, Calcagno E, Invernizzi R, Di Giovanni G, Esposito E, Vezzani A.
    Neuroscience; 2009 Jun 16; 161(1):293-300. PubMed ID: 19285115
    [Abstract] [Full Text] [Related]

  • 24. Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease.
    Pedersen WA, McCullers D, Culmsee C, Haughey NJ, Herman JP, Mattson MP.
    Neurobiol Dis; 2001 Jun 16; 8(3):492-503. PubMed ID: 11442356
    [Abstract] [Full Text] [Related]

  • 25. Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis.
    Wang R, Dineley KT, Sweatt JD, Zheng H.
    Neuroscience; 2004 Jun 16; 126(2):305-12. PubMed ID: 15207348
    [Abstract] [Full Text] [Related]

  • 26. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.
    Yu Z, Luo H, Fu W, Mattson MP.
    Exp Neurol; 1999 Feb 16; 155(2):302-14. PubMed ID: 10072306
    [Abstract] [Full Text] [Related]

  • 27. Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
    Dewachter I, Ris L, Croes S, Borghgraef P, Devijver H, Voets T, Nilius B, Godaux E, Van Leuven F.
    Neurobiol Aging; 2008 May 16; 29(5):639-52. PubMed ID: 17222948
    [Abstract] [Full Text] [Related]

  • 28. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug 16; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 29. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 16; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 30. Altered morphological and electrophysiological properties of Cajal-Retzius cells in cerebral cortex of embryonic Presenilin-1 knockout mice.
    Kilb W, Hartmann D, Saftig P, Luhmann HJ.
    Eur J Neurosci; 2004 Nov 16; 20(10):2749-56. PubMed ID: 15548218
    [Abstract] [Full Text] [Related]

  • 31. Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically.
    Grilli M, Diodato E, Lozza G, Brusa R, Casarini M, Uberti D, Rozmahel R, Westaway D, St George-Hyslop P, Memo M, Ongini E.
    Proc Natl Acad Sci U S A; 2000 Nov 07; 97(23):12822-7. PubMed ID: 11070093
    [Abstract] [Full Text] [Related]

  • 32. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 07; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 33. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons.
    Chan SL, Mayne M, Holden CP, Geiger JD, Mattson MP.
    J Biol Chem; 2000 Jun 16; 275(24):18195-200. PubMed ID: 10764737
    [Abstract] [Full Text] [Related]

  • 34. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun 16; 39(6):539-50. PubMed ID: 16620965
    [Abstract] [Full Text] [Related]

  • 35. Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake.
    Yang Y, Kinney GA, Spain WJ, Breitner JC, Cook DG.
    J Neurochem; 2004 Mar 16; 88(6):1361-72. PubMed ID: 15009636
    [Abstract] [Full Text] [Related]

  • 36. Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity.
    Maezawa I, Wang B, Hu Q, Martin GM, Jin LW, Oshima J.
    Pathol Int; 2002 Sep 16; 52(9):551-4. PubMed ID: 12406183
    [Abstract] [Full Text] [Related]

  • 37. Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro.
    Nakajima M, Miura M, Aosaki T, Shirasawa T.
    J Neurochem; 2001 Aug 16; 78(4):807-14. PubMed ID: 11520901
    [Abstract] [Full Text] [Related]

  • 38. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation.
    Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J.
    J Biol Chem; 2001 Apr 13; 276(15):11539-44. PubMed ID: 11278803
    [Abstract] [Full Text] [Related]

  • 39. Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.
    Veeraraghavalu K, Choi SH, Zhang X, Sisodia SS.
    Mol Neurodegener; 2013 Oct 20; 8():41. PubMed ID: 24138759
    [Abstract] [Full Text] [Related]

  • 40. Reduction of increased calcineurin activity rescues impaired homeostatic synaptic plasticity in presenilin 1 M146V mutant.
    Kim S, Violette CJ, Ziff EB.
    Neurobiol Aging; 2015 Dec 20; 36(12):3239-3246. PubMed ID: 26455952
    [Abstract] [Full Text] [Related]

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