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236 related items for PubMed ID: 9884064

  • 1. Orphan G-protein-coupled receptors: the next generation of drug targets?
    Wilson S, Bergsma DJ, Chambers JK, Muir AI, Fantom KG, Ellis C, Murdock PR, Herrity NC, Stadel JM.
    Br J Pharmacol; 1998 Dec; 125(7):1387-92. PubMed ID: 9884064
    [Abstract] [Full Text] [Related]

  • 2. Orphan G protein-coupled receptors: from DNA to drug targets.
    Shaaban S, Benton B.
    Curr Opin Drug Discov Devel; 2001 Sep; 4(5):535-47. PubMed ID: 12825450
    [Abstract] [Full Text] [Related]

  • 3. Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).
    Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN.
    Genomics; 2000 Jul 01; 67(1):8-18. PubMed ID: 10945465
    [Abstract] [Full Text] [Related]

  • 4. Use of constitutive G protein-coupled receptor activity for drug discovery.
    Chen G, Way J, Armour S, Watson C, Queen K, Jayawickreme CK, Chen WJ, Kenakin T.
    Mol Pharmacol; 2000 Jan 01; 57(1):125-34. PubMed ID: 10617687
    [Abstract] [Full Text] [Related]

  • 5. The G protein-coupled receptor repertoires of human and mouse.
    Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA.
    Proc Natl Acad Sci U S A; 2003 Apr 15; 100(8):4903-8. PubMed ID: 12679517
    [Abstract] [Full Text] [Related]

  • 6. Ligand screening system using fusion proteins of G protein-coupled receptors with G protein alpha subunits.
    Suga H, Haga T.
    Neurochem Int; 2007 Apr 15; 51(2-4):140-64. PubMed ID: 17659814
    [Abstract] [Full Text] [Related]

  • 7. Molecular approaches to receptors as targets for drug discovery.
    Herz JM, Thomsen WJ, Yarbrough GG.
    J Recept Signal Transduct Res; 1997 Sep 15; 17(5):671-776. PubMed ID: 9292776
    [Abstract] [Full Text] [Related]

  • 8. Alternative drug discovery approaches for orphan GPCRs.
    Levoye A, Jockers R.
    Drug Discov Today; 2008 Jan 15; 13(1-2):52-8. PubMed ID: 18190864
    [Abstract] [Full Text] [Related]

  • 9. Virtual screen for ligands of orphan G protein-coupled receptors.
    Bock JR, Gough DA.
    J Chem Inf Model; 2005 Jan 15; 45(5):1402-14. PubMed ID: 16180917
    [Abstract] [Full Text] [Related]

  • 10. Drug design strategies for targeting G-protein-coupled receptors.
    Klabunde T, Hessler G.
    Chembiochem; 2002 Oct 04; 3(10):928-44. PubMed ID: 12362358
    [Abstract] [Full Text] [Related]

  • 11. Receptor autoradiography as mean to explore the possible functional relevance of neuropeptides: focus on new agonists and antagonists to study natriuretic peptides, neuropeptide Y and calcitonin gene-related peptides.
    Dumont Y, Chabot JG, Quirion R.
    Peptides; 2004 Mar 04; 25(3):365-91. PubMed ID: 15134861
    [Abstract] [Full Text] [Related]

  • 12. Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors.
    Seifert R, Wenzel-Seifert K.
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Nov 04; 366(5):381-416. PubMed ID: 12382069
    [Abstract] [Full Text] [Related]

  • 13. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R, Wolff M, Tautermann CS, Bieler M.
    Drug Discov Today; 2009 Mar 04; 14(5-6):231-40. PubMed ID: 19121411
    [Abstract] [Full Text] [Related]

  • 14. The future of G protein-coupled receptors as targets in drug discovery.
    Lundstrom K.
    IDrugs; 2005 Nov 04; 8(11):909-13. PubMed ID: 16254784
    [Abstract] [Full Text] [Related]

  • 15. Structure-based identification of binding sites, native ligands and potential inhibitors for G-protein coupled receptors.
    Cavasotto CN, Orry AJ, Abagyan RA.
    Proteins; 2003 May 15; 51(3):423-33. PubMed ID: 12696053
    [Abstract] [Full Text] [Related]

  • 16. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
    Kristiansen K.
    Pharmacol Ther; 2004 Jul 15; 103(1):21-80. PubMed ID: 15251227
    [Abstract] [Full Text] [Related]

  • 17. The 7 TM G-protein-coupled receptor target family.
    Jacoby E, Bouhelal R, Gerspacher M, Seuwen K.
    ChemMedChem; 2006 Aug 15; 1(8):761-82. PubMed ID: 16902930
    [Abstract] [Full Text] [Related]

  • 18. Bioinformatics-based discovery and identification of new biologically active peptides for GPCR deorphanization.
    Colette J, Avé E, Grenier-Boley B, Coquel AS, Lesellier K, Puget K.
    J Pept Sci; 2007 Sep 15; 13(9):568-74. PubMed ID: 17694568
    [Abstract] [Full Text] [Related]

  • 19. Relaxin-3, INSL5, and their receptors.
    Liu C, Lovenberg TW.
    Results Probl Cell Differ; 2008 Sep 15; 46():213-37. PubMed ID: 18236022
    [Abstract] [Full Text] [Related]

  • 20. Multiplex GPCR assay in reverse transfection cell microarrays.
    Mishina YM, Wilson CJ, Bruett L, Smith JJ, Stoop-Myer C, Jong S, Amaral LP, Pedersen R, Lyman SK, Myer VE, Kreider BL, Thompson CM.
    J Biomol Screen; 2004 Apr 15; 9(3):196-207. PubMed ID: 15140381
    [Abstract] [Full Text] [Related]

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