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Journal Abstract Search
146 related items for PubMed ID: 9886077
1. Dual roles of proteasome in the metabolism of presenilin 1. Honda T, Yasutake K, Nihonmatsu N, Mercken M, Takahashi H, Murayama O, Murayama M, Sato K, Omori A, Tsubuki S, Saido TC, Takashima A. J Neurochem; 1999 Jan; 72(1):255-61. PubMed ID: 9886077 [Abstract] [Full Text] [Related]
2. Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A beta 42 recovery from human cells. Marambaud P, Ancolio K, Lopez-Perez E, Checler F. Mol Med; 1998 Mar; 4(3):147-57. PubMed ID: 9562973 [Abstract] [Full Text] [Related]
3. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome. da Costa CA, Ancolio K, Checler F. Mol Med; 1999 Mar; 5(3):160-8. PubMed ID: 10404513 [Abstract] [Full Text] [Related]
4. Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation. Steiner H, Capell A, Pesold B, Citron M, Kloetzel PM, Selkoe DJ, Romig H, Mendla K, Haass C. J Biol Chem; 1998 Nov 27; 273(48):32322-31. PubMed ID: 9822712 [Abstract] [Full Text] [Related]
5. Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome. Van Gassen G, De Jonghe C, Pype S, Van Criekinge W, Julliams A, Vanderhoeven I, Woodrow S, Beyaert R, Huylebroeck D, Van Broeckhoven C. Neurobiol Dis; 1999 Oct 27; 6(5):376-91. PubMed ID: 10527805 [Abstract] [Full Text] [Related]
6. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome. Marambaud P, Alves da Costa C, Ancolio K, Checler F. Biochem Biophys Res Commun; 1998 Nov 09; 252(1):134-8. PubMed ID: 9813158 [Abstract] [Full Text] [Related]
7. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells. Kim TW, Pettingell WH, Hallmark OG, Moir RD, Wasco W, Tanzi RE. J Biol Chem; 1997 Apr 25; 272(17):11006-10. PubMed ID: 9110991 [Abstract] [Full Text] [Related]
8. Familial Alzheimer's disease-associated mutations block translocation of full-length presenilin 1 to the nuclear envelope. Honda T, Nihonmatsu N, Yasutake K, Ohtake A, Sato K, Tanaka S, Murayama O, Murayama M, Takashima A. Neurosci Res; 2000 Jun 25; 37(2):101-11. PubMed ID: 10867173 [Abstract] [Full Text] [Related]
9. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue. Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ. Neurobiol Dis; 1997 Jun 25; 3(4):325-37. PubMed ID: 9173929 [Abstract] [Full Text] [Related]
10. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL. Science; 1995 May 05; 268(5211):726-31. PubMed ID: 7732382 [Abstract] [Full Text] [Related]
12. Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease. Evin G, Sharples RA, Weidemann A, Reinhard FB, Carbone V, Culvenor JG, Holsinger RM, Sernee MF, Beyreuther K, Masters CL. Biochemistry; 2001 Jul 27; 40(28):8359-68. PubMed ID: 11444983 [Abstract] [Full Text] [Related]
13. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Crystal AS, Morais VA, Fortna RR, Carlin D, Pierson TC, Wilson CA, Lee VM, Doms RW. Biochemistry; 2004 Mar 30; 43(12):3555-63. PubMed ID: 15035625 [Abstract] [Full Text] [Related]
14. Presenilin 1 cleavage is a universal event in human organs. Okochi M, Sahara N, Kametani F, Usami M, Arai T, Tanaka K, Ishii K, Yamamoto A, Mori H. Neurobiol Aging; 1998 Mar 30; 19(1 Suppl):S3-10. PubMed ID: 9562459 [Abstract] [Full Text] [Related]
15. Proteolytic processing and degradation of human presenilin-1 expressed in yeast. Song S, Ohba M, Saito Y, Honda T, Takashima A, Takahashi H. Neurosci Lett; 2000 Mar 17; 282(1-2):65-8. PubMed ID: 10713397 [Abstract] [Full Text] [Related]
16. The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses. Schwarz K, de Giuli R, Schmidtke G, Kostka S, van den Broek M, Kim KB, Crews CM, Kraft R, Groettrup M. J Immunol; 2000 Jun 15; 164(12):6147-57. PubMed ID: 10843664 [Abstract] [Full Text] [Related]
17. Impaired proteolytic processing of presenilin-1 in chromosome 14-linked familial Alzheimer's disease patient lymphocytes. Takahashi H, Mercken M, Honda T, Saito Y, Murayama M, Song S, Takashima A. Neurosci Lett; 1999 Jan 29; 260(2):121-4. PubMed ID: 10025714 [Abstract] [Full Text] [Related]
18. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Kim TW, Pettingell WH, Jung YK, Kovacs DM, Tanzi RE. Science; 1997 Jul 18; 277(5324):373-6. PubMed ID: 9219695 [Abstract] [Full Text] [Related]