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285 related items for PubMed ID: 9887328
21. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP. Brain; 2015 Dec; 138(Pt 12):3632-53. PubMed ID: 26490331 [Abstract] [Full Text] [Related]
22. Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease. Petrasch-Parwez E, Nguyen HP, Löbbecke-Schumacher M, Habbes HW, Wieczorek S, Riess O, Andres KH, Dermietzel R, Von Hörsten S. J Comp Neurol; 2007 Apr 10; 501(5):716-30. PubMed ID: 17299753 [Abstract] [Full Text] [Related]
23. Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model. Weiss KR, Kimura Y, Lee WC, Littleton JT. Genetics; 2012 Feb 10; 190(2):581-600. PubMed ID: 22095086 [Abstract] [Full Text] [Related]
26. Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease. Trushina E, Heldebrant MP, Perez-Terzic CM, Bortolon R, Kovtun IV, Badger JD, Terzic A, Estévez A, Windebank AJ, Dyer RB, Yao J, McMurray CT. Proc Natl Acad Sci U S A; 2003 Oct 14; 100(21):12171-6. PubMed ID: 14527999 [Abstract] [Full Text] [Related]
28. Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene. Tanaka K, Shouguchi-Miyata J, Miyamoto N, Ikeda JE. J Biol Chem; 2004 Feb 20; 279(8):7275-86. PubMed ID: 14625278 [Abstract] [Full Text] [Related]
29. Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation. De Rooij KE, Dorsman JC, Smoor MA, Den Dunnen JT, Van Ommen GJ. Hum Mol Genet; 1996 Aug 20; 5(8):1093-9. PubMed ID: 8842726 [Abstract] [Full Text] [Related]
30. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ. J Neurosci; 2008 Mar 12; 28(11):2783-92. PubMed ID: 18337408 [Abstract] [Full Text] [Related]
31. The influence of huntingtin protein size on nuclear localization and cellular toxicity. Hackam AS, Singaraja R, Wellington CL, Metzler M, McCutcheon K, Zhang T, Kalchman M, Hayden MR. J Cell Biol; 1998 Jun 01; 141(5):1097-105. PubMed ID: 9606203 [Abstract] [Full Text] [Related]
39. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease. Ho LW, Brown R, Maxwell M, Wyttenbach A, Rubinsztein DC. J Med Genet; 2001 Jul 01; 38(7):450-2. PubMed ID: 11432963 [Abstract] [Full Text] [Related]