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122 related items for PubMed ID: 9890979

  • 1. Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway.
    Mizuguchi H, Cook PF, Tai CH, Hasemann CA, Uyeda K.
    J Biol Chem; 1999 Jan 22; 274(4):2166-75. PubMed ID: 9890979
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
    Yuen MH, Mizuguchi H, Lee YH, Cook PF, Uyeda K, Hasemann CA.
    J Biol Chem; 1999 Jan 22; 274(4):2176-84. PubMed ID: 9890980
    [Abstract] [Full Text] [Related]

  • 3. Mutations in the charged residues of the amino terminus of rat liver fructose 6-phosphate,2-kinase:Fructose 2,6-bisphosphatase: effects on regulation.
    Wu RF, Uyeda K.
    Arch Biochem Biophys; 1999 Nov 01; 371(1):15-23. PubMed ID: 10525284
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  • 4. Glu327 is part of a catalytic triad in rat liver fructose-2,6-bisphosphatase.
    Lin K, Li L, Correia JJ, Pilkis SJ.
    J Biol Chem; 1992 Apr 05; 267(10):6556-62. PubMed ID: 1313012
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  • 5. Lysine 356 is a critical residue for binding the C-6 phospho group of fructose 2,6-bisphosphate to the fructose-2,6-bisphosphatase domain of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
    Li L, Lin K, Correia JJ, Pilkis SJ.
    J Biol Chem; 1992 Aug 15; 267(23):16669-75. PubMed ID: 1322913
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  • 6. Identification of transient intermediates in the bisphosphatase reaction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by 31P-NMR spectroscopy.
    Okar DA, Kakalis LT, Narula SS, Armitage IM, Pilkis SJ.
    Biochem J; 1995 May 15; 308 ( Pt 1)(Pt 1):189-95. PubMed ID: 7755565
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  • 7. Hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Use of site-directed mutagenesis to evaluate the roles of His-258 and His-392 in catalysis.
    Tauler A, Lin K, Pilkis SJ.
    J Biol Chem; 1990 Sep 15; 265(26):15617-22. PubMed ID: 2168419
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  • 9. Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase.
    Sakurai M, Cook PF, Haseman CA, Uyeda K.
    Biochemistry; 2000 Dec 26; 39(51):16238-43. PubMed ID: 11123954
    [Abstract] [Full Text] [Related]

  • 10. Mechanism of the bisphosphatase reaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase probed by (1)H-(15)N NMR spectroscopy.
    Okar DA, Live DH, Devany MH, Lange AJ.
    Biochemistry; 2000 Aug 15; 39(32):9754-62. PubMed ID: 10933792
    [Abstract] [Full Text] [Related]

  • 11. Hexose phosphate binding sites of fructose 6-phosphate,2-kinase:fructose 2,6-bisphosphatase.
    Tsujikawa T, Watanabe F, Uyeda K.
    Biochemistry; 1995 May 16; 34(19):6389-93. PubMed ID: 7756268
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  • 13. Hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. The role of surface loop basic residues in substrate binding to the fructose-2,6-bisphosphatase domain.
    Li L, Lin K, Pilkis J, Correia JJ, Pilkis SJ.
    J Biol Chem; 1992 Oct 25; 267(30):21588-94. PubMed ID: 1328239
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  • 14. Arg-257 and Arg-307 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bind the C-2 phospho group of fructose-2,6-bisphosphate in the fructose-2,6-bisphosphatase domain.
    Lin K, Li L, Correia JJ, Pilkis SJ.
    J Biol Chem; 1992 Sep 25; 267(27):19163-71. PubMed ID: 1326547
    [Abstract] [Full Text] [Related]

  • 15. Study of the roles of Arg-104 and Arg-225 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by site-directed mutagenesis.
    Rider MH, Crepin KM, De Cloedt M, Bertrand L, Vertommen D, Hue L.
    Biochem J; 1995 Jul 01; 309 ( Pt 1)(Pt 1):341-6. PubMed ID: 7619077
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  • 17. Glucose-stimulated synthesis of fructose 2,6-bisphosphate in rat liver. Dephosphorylation of fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase and activation by a sugar phosphate.
    Nishimura M, Fedorov S, Uyeda K.
    J Biol Chem; 1994 Oct 21; 269(42):26100-6. PubMed ID: 7929321
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  • 18. Purification and characterization of a novel xylulose 5-phosphate-activated protein phosphatase catalyzing dephosphorylation of fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase.
    Nishimura M, Uyeda K.
    J Biol Chem; 1995 Nov 03; 270(44):26341-6. PubMed ID: 7592845
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  • 20. Oscillation in fructose 2,6-bisphosphate levels and in the phosphorylation states of fructose 6-phosphate,2-kinase:fructose-2,6-bisphosphatase in ischemic rat liver.
    Fedorov S, Uyeda K.
    J Biol Chem; 1992 Oct 15; 267(29):20826-30. PubMed ID: 1328212
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