These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants. Haskell-Luevano C, Cone RD, Monck EK, Wan YP. Biochemistry; 2001 May 22; 40(20):6164-79. PubMed ID: 11352754 [Abstract] [Full Text] [Related]
3. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor. Yang Y, Chen M, Lai Y, Gantz I, Yagmurlu A, Georgeson KE, Harmon CM. Mol Pharmacol; 2003 Jul 22; 64(1):94-103. PubMed ID: 12815165 [Abstract] [Full Text] [Related]
6. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist. Frändberg PA, Doufexis M, Kapas S, Chhajlani V. Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737 [Abstract] [Full Text] [Related]
7. Down-regulation of melanocortin receptor signaling mediated by the amino terminus of Agouti protein in Xenopus melanophores. Ollmann MM, Barsh GS. J Biol Chem; 1999 May 28; 274(22):15837-46. PubMed ID: 10336487 [Abstract] [Full Text] [Related]
8. Chimeras of the agouti-related protein: insights into agonist and antagonist selectivity of melanocortin receptors. Jackson PJ, Yu B, Hunrichs B, Thompson DA, Chai B, Gantz I, Millhauser GL. Peptides; 2005 Oct 28; 26(10):1978-87. PubMed ID: 16009463 [Abstract] [Full Text] [Related]
9. The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs. Klovins J, Haitina T, Fridmanis D, Kilianova Z, Kapa I, Fredriksson R, Gallo-Payet N, Schiöth HB. Mol Biol Evol; 2004 Mar 28; 21(3):563-79. PubMed ID: 14694081 [Abstract] [Full Text] [Related]
10. Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor. Joseph CG, Bauzo RM, Xiang Z, Shaw AM, Millard WJ, Haskell-Luevano C. Peptides; 2003 Feb 28; 24(2):263-70. PubMed ID: 12668211 [Abstract] [Full Text] [Related]
11. Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors. Yang Z, Tao YX. Biochim Biophys Acta; 2016 Sep 28; 1862(9):1485-94. PubMed ID: 27208795 [Abstract] [Full Text] [Related]
12. Contribution of melanocortin receptor exoloops to Agouti-related protein binding. Yang YK, Dickinson CJ, Zeng Q, Li JY, Thompson DA, Gantz I. J Biol Chem; 1999 May 14; 274(20):14100-6. PubMed ID: 10318826 [Abstract] [Full Text] [Related]
14. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity. Joseph CG, Wilczynski A, Holder JR, Xiang Z, Bauzo RM, Scott JW, Haskell-Luevano C. Peptides; 2003 Dec 14; 24(12):1899-908. PubMed ID: 15127941 [Abstract] [Full Text] [Related]
15. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein. Oosterom J, Garner KM, den Dekker WK, Nijenhuis WA, Gispen WH, Burbach JP, Barsh GS, Adan RA. J Biol Chem; 2001 Jan 12; 276(2):931-6. PubMed ID: 11024027 [Abstract] [Full Text] [Related]
16. Agouti antagonism of melanocortin-4 receptor: greater effect with desacetyl-alpha-melanocyte-stimulating hormone (MSH) than with alpha-MSH. Mountjoy KG, Willard DH, Wilkison WO. Endocrinology; 1999 May 12; 140(5):2167-72. PubMed ID: 10218968 [Abstract] [Full Text] [Related]
17. Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Boston BA, Cone RD. Endocrinology; 1996 May 12; 137(5):2043-50. PubMed ID: 8612546 [Abstract] [Full Text] [Related]
18. Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo. Ollmann MM, Lamoreux ML, Wilson BD, Barsh GS. Genes Dev; 1998 Feb 01; 12(3):316-30. PubMed ID: 9450927 [Abstract] [Full Text] [Related]
19. AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor. Nijenhuis WA, Oosterom J, Adan RA. Mol Endocrinol; 2001 Jan 01; 15(1):164-71. PubMed ID: 11145747 [Abstract] [Full Text] [Related]