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Journal Abstract Search

381 related items for PubMed ID: 9893962

  • 21. A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies.
    Schwartz G, Johnson TR, Goetz A, Burris H, Smetzer L, Lampkin T, Sailstad J, Hohneker JA, Von Hoff DD, Rowinsky EK.
    Clin Cancer Res; 2001 Jul; 7(7):1901-11. PubMed ID: 11448903
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  • 23. Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft.
    Stribbling SM, Martin J, Pedley RB, Boden JA, Sharma SK, Springer CJ.
    Cancer Chemother Pharmacol; 1997 Jul; 40(4):277-84. PubMed ID: 9225945
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  • 24. Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs.
    Schultz RM, Chen VJ, Bewley JR, Roberts EF, Shih C, Dempsey JA.
    Semin Oncol; 1999 Apr; 26(2 Suppl 6):68-73. PubMed ID: 10598558
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  • 25. Comparison of thymidylate synthase (TS) protein up-regulation after exposure to TS inhibitors in normal and tumor cell lines and tissues.
    Welsh SJ, Titley J, Brunton L, Valenti M, Monaghan P, Jackman AL, Aherne GW.
    Clin Cancer Res; 2000 Jun; 6(6):2538-46. PubMed ID: 10873110
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  • 27. Engineering a thermostable human prolyl endopeptidase for antibody-directed enzyme prodrug therapy.
    Heinis C, Alessi P, Neri D.
    Biochemistry; 2004 May 25; 43(20):6293-303. PubMed ID: 15147213
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  • 29. Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
    Davies LC, Friedlos F, Hedley D, Martin J, Ogilvie LM, Scanlon IJ, Springer CJ.
    J Med Chem; 2005 Aug 11; 48(16):5321-8. PubMed ID: 16078849
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  • 31. Antibody-directed enzyme prodrug therapy (ADEPT) with mustard prodrugs.
    Springer CJ, Niculescu-Duvaz I.
    Anticancer Drug Des; 1995 Jul 11; 10(5):361-72. PubMed ID: 7639927
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  • 37. Role of thymidylate synthase in the antitumor activity of the multitargeted antifolate, LY231514.
    Schultz RM, Patel VF, Worzalla JF, Shih C.
    Anticancer Res; 1999 Jul 11; 19(1A):437-43. PubMed ID: 10226579
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  • 38. Effect of methotrexate-monoclonal anti-prostatic acid phosphatase antibody conjugate on human prostate tumor.
    Deguchi T, Chu TM, Leong SS, Horoszewicz JS, Lee CL.
    Cancer Res; 1986 Aug 11; 46(8):3751-5. PubMed ID: 3731053
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  • 39. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B, Pinedo HM, van Hensbergen Y, Smid K, Telleman F, Schoenmakers PS, van der Wilt CL, van Laar JA, Noordhuis P, Jansen G, Peters GJ.
    Clin Cancer Res; 1999 Mar 11; 5(3):643-54. PubMed ID: 10100718
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