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327 related items for PubMed ID: 9894613

  • 1. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts.
    An B, Goldfarb RH, Siman R, Dou QP.
    Cell Death Differ; 1998 Dec; 5(12):1062-75. PubMed ID: 9894613
    [Abstract] [Full Text] [Related]

  • 2. CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice.
    Sun J, Nam S, Lee CS, Li B, Coppola D, Hamilton AD, Dou QP, Sebti SM.
    Cancer Res; 2001 Feb 15; 61(4):1280-4. PubMed ID: 11245420
    [Abstract] [Full Text] [Related]

  • 3. Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2.
    Monney L, Otter I, Olivier R, Ozer HL, Haas AL, Omura S, Borner C.
    J Biol Chem; 1998 Mar 13; 273(11):6121-31. PubMed ID: 9497330
    [Abstract] [Full Text] [Related]

  • 4. Induction of G1 arrest and apoptosis in human jurkat T cells by pentagalloylglucose through inhibiting proteasome activity and elevating p27Kip1, p21Cip1/WAF1, and Bax proteins.
    Chen WJ, Lin JK.
    J Biol Chem; 2004 Apr 02; 279(14):13496-505. PubMed ID: 14726525
    [Abstract] [Full Text] [Related]

  • 5. Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells.
    Kitagawa H, Tani E, Ikemoto H, Ozaki I, Nakano A, Omura S.
    FEBS Lett; 1999 Jan 25; 443(2):181-6. PubMed ID: 9989601
    [Abstract] [Full Text] [Related]

  • 6. Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest.
    Loubat A, Rochet N, Turchi L, Rezzonico R, Far DF, Auberger P, Rossi B, Ponzio G.
    Oncogene; 1999 Jun 03; 18(22):3324-33. PubMed ID: 10362353
    [Abstract] [Full Text] [Related]

  • 7. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo.
    Nam S, Smith DM, Dou QP.
    J Biol Chem; 2001 Apr 20; 276(16):13322-30. PubMed ID: 11278274
    [Abstract] [Full Text] [Related]

  • 8. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
    An WG, Hwang SG, Trepel JB, Blagosklonny MV.
    Leukemia; 2000 Jul 20; 14(7):1276-83. PubMed ID: 10914553
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of proteasome function induced apoptosis in gastric cancer.
    Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK.
    Int J Cancer; 2001 Aug 15; 93(4):481-8. PubMed ID: 11477551
    [Abstract] [Full Text] [Related]

  • 10. Role of proteasomes in T cell activation and proliferation.
    Wang X, Luo H, Chen H, Duguid W, Wu J.
    J Immunol; 1998 Jan 15; 160(2):788-801. PubMed ID: 9551914
    [Abstract] [Full Text] [Related]

  • 11. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y, Takata T, Ogawa I, Kaneda T, Sato S, Takekoshi T, Zhao M, Miyauchi M, Nikai H.
    Clin Cancer Res; 2000 Mar 15; 6(3):916-23. PubMed ID: 10741716
    [Abstract] [Full Text] [Related]

  • 12. Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
    Eymin B, Sordet O, Droin N, Munsch B, Haugg M, Van de Craen M, Vandenabeele P, Solary E.
    Oncogene; 1999 Aug 26; 18(34):4839-47. PubMed ID: 10490817
    [Abstract] [Full Text] [Related]

  • 13. Transforming growth factor beta1 attenuates ceramide-induced CPP32/Yama activation and apoptosis in human leukaemic HL-60 cells.
    Kuo ML, Chen CW, Jee SH, Chuang SE, Cheng AL.
    Biochem J; 1997 Nov 01; 327 ( Pt 3)(Pt 3):663-7. PubMed ID: 9581540
    [Abstract] [Full Text] [Related]

  • 14. Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways.
    Bogner C, Schneller F, Hipp S, Ringshausen I, Peschel C, Decker T.
    Exp Hematol; 2003 Mar 01; 31(3):218-25. PubMed ID: 12644019
    [Abstract] [Full Text] [Related]

  • 15. Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential.
    Meeran SM, Katiyar SK.
    Exp Dermatol; 2007 May 01; 16(5):405-15. PubMed ID: 17437483
    [Abstract] [Full Text] [Related]

  • 16. Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
    Wagenknecht B, Hermisson M, Eitel K, Weller M.
    Cell Physiol Biochem; 1999 May 01; 9(3):117-25. PubMed ID: 10494025
    [Abstract] [Full Text] [Related]

  • 17. Induction of CDK inhibitors (p21(WAF1) and p27(Kip1)) and Bak in the beta-lapachone-induced apoptosis of human prostate cancer cells.
    Don MJ, Chang YH, Chen KK, Ho LK, Chau YP.
    Mol Pharmacol; 2001 Apr 01; 59(4):784-94. PubMed ID: 11259623
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.
    Zhang XM, Lin H, Chen C, Chen BD.
    Biochem J; 1999 May 15; 340 ( Pt 1)(Pt 1):127-33. PubMed ID: 10229667
    [Abstract] [Full Text] [Related]

  • 19. Activation of the cell death program by inhibition of proteasome function.
    Drexler HC.
    Proc Natl Acad Sci U S A; 1997 Feb 04; 94(3):855-60. PubMed ID: 9023346
    [Abstract] [Full Text] [Related]

  • 20. Concomitant differentiation and partial proteasome inhibition trigger apoptosis in neuroblastoma cells.
    Nahreini P, Andreatta C, Hanson A, Prasad KN.
    J Neurooncol; 2003 May 04; 63(1):15-23. PubMed ID: 12814250
    [Abstract] [Full Text] [Related]

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