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Journal Abstract Search


617 related items for PubMed ID: 9914503

  • 1. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
    Serveau C, Lalmanach G, Hirata I, Scharfstein J, Juliano MA, Gauthier F.
    Eur J Biochem; 1999 Jan; 259(1-2):275-80. PubMed ID: 9914503
    [Abstract] [Full Text] [Related]

  • 2. Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.
    Nery ED, Juliano MA, Meldal M, Svendsen I, Scharfstein J, Walmsley A, Juliano L.
    Biochem J; 1997 Apr 15; 323 ( Pt 2)(Pt 2):427-33. PubMed ID: 9163334
    [Abstract] [Full Text] [Related]

  • 3. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors.
    Serveau C, Lalmanach G, Juliano MA, Scharfstein J, Juliano L, Gauthier F.
    Biochem J; 1996 Feb 01; 313 ( Pt 3)(Pt 3):951-6. PubMed ID: 8611180
    [Abstract] [Full Text] [Related]

  • 4. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
    Lalmanach G, Mayer R, Serveau C, Scharfstein J, Gauthier F.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
    [Abstract] [Full Text] [Related]

  • 5. A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi.
    Chagas JR, Authie E, Serveau C, Lalmanach G, Juliano L, Gauthier F.
    Mol Biochem Parasitol; 1997 Sep 01; 88(1-2):85-94. PubMed ID: 9274870
    [Abstract] [Full Text] [Related]

  • 6. Probing cathepsin K activity with a selective substrate spanning its active site.
    Lecaille F, Weidauer E, Juliano MA, Brömme D, Lalmanach G.
    Biochem J; 2003 Oct 15; 375(Pt 2):307-12. PubMed ID: 12837132
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L.
    Meldal M, Svendsen IB, Juliano L, Juliano MA, Nery ED, Scharfstein J.
    J Pept Sci; 1998 Apr 15; 4(2):83-91. PubMed ID: 9620612
    [Abstract] [Full Text] [Related]

  • 8. Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids.
    Lecaille F, Authié E, Moreau T, Serveau C, Gauthier F, Lalmanach G.
    Eur J Biochem; 2001 May 15; 268(9):2733-41. PubMed ID: 11322895
    [Abstract] [Full Text] [Related]

  • 9. Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.
    Portaro FC, Santos AB, Cezari MH, Juliano MA, Juliano L, Carmona E.
    Biochem J; 2000 Apr 01; 347 Pt 1(Pt 1):123-9. PubMed ID: 10727410
    [Abstract] [Full Text] [Related]

  • 10. Comparison of the specificity, stability and individual rate constants with respective activation parameters for the peptidase activity of cruzipain and its recombinant form, cruzain, from Trypanosoma cruzi.
    Judice WA, Cezari MH, Lima AP, Scharfstein J, Chagas JR, Tersariol IL, Juliano MA, Juliano L.
    Eur J Biochem; 2001 Dec 01; 268(24):6578-86. PubMed ID: 11737212
    [Abstract] [Full Text] [Related]

  • 11. Molecular modeling and substrate specificity of discrete cruzipain-like and cathepsin L-like cysteine proteinases of the human blood fluke Schistosoma mansoni.
    Brady CP, Brinkworth RI, Dalton JP, Dowd AJ, Verity CK, Brindley PJ.
    Arch Biochem Biophys; 2000 Aug 01; 380(1):46-55. PubMed ID: 10900131
    [Abstract] [Full Text] [Related]

  • 12. Some kinetic properties of a cysteine proteinase (cruzipain) from Trypanosoma cruzi.
    Cazzulo JJ, Cazzulo Franke MC, Martínez J, Franke de Cazzulo BM.
    Biochim Biophys Acta; 1990 Feb 09; 1037(2):186-91. PubMed ID: 2407295
    [Abstract] [Full Text] [Related]

  • 13. Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana.
    Alves LC, Judice WA, St Hilaire PM, Meldal M, Sanderson SJ, Mottram JC, Coombs GH, Juliano L, Juliano MA.
    Mol Biochem Parasitol; 2001 Aug 09; 116(1):1-9. PubMed ID: 11463460
    [Abstract] [Full Text] [Related]

  • 14. Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases.
    Yong V, Schmitz V, Vannier-Santos MA, de Lima AP, Lalmanach G, Juliano L, Gauthier F, Scharfstein J.
    Mol Biochem Parasitol; 2000 Jun 09; 109(1):47-59. PubMed ID: 10924756
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.
    Melo RL, Alves LC, Del Nery E, Juliano L, Juliano MA.
    Anal Biochem; 2001 Jun 01; 293(1):71-7. PubMed ID: 11373081
    [Abstract] [Full Text] [Related]

  • 16. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
    Lima AP, dos Reis FC, Serveau C, Lalmanach G, Juliano L, Ménard R, Vernet T, Thomas DY, Storer AC, Scharfstein J.
    Mol Biochem Parasitol; 2001 Apr 25; 114(1):41-52. PubMed ID: 11356512
    [Abstract] [Full Text] [Related]

  • 17. Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases.
    Lalmanach G, Serveau C, Brillard-Bourdet M, Chagas JR, Mayer R, Juliano L, Gauthier F.
    J Protein Chem; 1995 Nov 25; 14(8):645-53. PubMed ID: 8747425
    [Abstract] [Full Text] [Related]

  • 18. Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi.
    Del Nery E, Juliano MA, Lima AP, Scharfstein J, Juliano L.
    J Biol Chem; 1997 Oct 10; 272(41):25713-8. PubMed ID: 9325296
    [Abstract] [Full Text] [Related]

  • 19. Analysis of the S(2) subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, using fluorescent substrates containing non-natural basic amino acids.
    Alves LC, Melo RL, Cezari MH, Sanderson SJ, Mottram JC, Coombs GH, Juliano L, Juliano MA.
    Mol Biochem Parasitol; 2001 Oct 10; 117(2):137-43. PubMed ID: 11606223
    [Abstract] [Full Text] [Related]

  • 20. Substrate inhibition of cruzipain is not affected by the C-terminal domain.
    Stoka V, McKerrow JH, Cazzulo JJ, Turk V.
    FEBS Lett; 1998 Jun 12; 429(2):129-33. PubMed ID: 9650575
    [Abstract] [Full Text] [Related]


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