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Journal Abstract Search

179 related items for PubMed ID: 9918200

  • 1. Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) alpha and TGF alpha/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis.
    Nørgaard P, Law B, Joseph H, Page DL, Shyr Y, Mays D, Pietenpol JA, Kohl NE, Oliff A, Coffey RJ, Poulsen HS, Moses HL.
    Clin Cancer Res; 1999 Jan; 5(1):35-42. PubMed ID: 9918200
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  • 4. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS, Ahmed MM.
    Oncogene; 2002 Nov 07; 21(51):7883-90. PubMed ID: 12420225
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  • 5. Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice.
    Mangues R, Corral T, Kohl NE, Symmans WF, Lu S, Malumbres M, Gibbs JB, Oliff A, Pellicer A.
    Cancer Res; 1998 Mar 15; 58(6):1253-9. PubMed ID: 9515813
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  • 6. Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.
    Feldkamp MM, Lau N, Guha A.
    Oncogene; 1999 Dec 09; 18(52):7514-26. PubMed ID: 10602510
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  • 8. A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis.
    Barrington RE, Subler MA, Rands E, Omer CA, Miller PJ, Hundley JE, Koester SK, Troyer DA, Bearss DJ, Conner MW, Gibbs JB, Hamilton K, Koblan KS, Mosser SD, O'Neill TJ, Schaber MD, Senderak ET, Windle JJ, Oliff A, Kohl NE.
    Mol Cell Biol; 1998 Jan 09; 18(1):85-92. PubMed ID: 9418856
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  • 9. Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1.
    DuHadaway JB, Du W, Donover S, Baker J, Liu AX, Sharp DM, Muller AJ, Prendergast GC.
    Oncogene; 2003 Jun 05; 22(23):3578-88. PubMed ID: 12789266
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  • 10. p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
    Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.
    Cancer Res; 2006 May 01; 66(9):4672-80. PubMed ID: 16651418
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  • 11. Maspin expression inversely correlates with breast tumor progression in MMTV/TGF-alpha transgenic mouse model.
    Reddy KB, McGowen R, Schuger L, Visscher D, Sheng S.
    Oncogene; 2001 Oct 04; 20(45):6538-43. PubMed ID: 11641778
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  • 12. Cooperation of TGF alpha and c-Myc in mouse mammary tumorigenesis: coordinated stimulation of growth and suppression of apoptosis.
    Amundadottir LT, Nass SJ, Berchem GJ, Johnson MD, Dickson RB.
    Oncogene; 1996 Aug 15; 13(4):757-65. PubMed ID: 8761297
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  • 13. Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer.
    Liu M, Howes A, Lesperance J, Stallcup WB, Hauser CA, Kadoya K, Oshima RG, Abraham RT.
    Cancer Res; 2005 Jun 15; 65(12):5325-36. PubMed ID: 15958580
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  • 14. The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells.
    Bolick SC, Landowski TH, Boulware D, Oshiro MM, Ohkanda J, Hamilton AD, Sebti SM, Dalton WS.
    Leukemia; 2003 Feb 15; 17(2):451-7. PubMed ID: 12592346
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  • 15. Induction of a variety of preneoplasias and tumours in the mammary glands of transgenic rats.
    Davies BR, Warren JR, Schmidt G, Rudland PS.
    Biochem Soc Symp; 1998 Feb 15; 63():167-84. PubMed ID: 9513721
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  • 16. In vitro and in vivo antisense-mediated growth inhibition of a mammary adenocarcinoma from MMTV-neu transgenic mice.
    Sacco MG, Barbieri O, Piccini D, Noviello E, Zoppé M, Zucchi I, Frattini A, Villa A, Vezzoni P.
    Gene Ther; 1998 Mar 15; 5(3):388-93. PubMed ID: 9614559
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  • 17. MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
    Zhou H, Chen WD, Qin X, Lee K, Liu L, Markowitz SD, Gerson SL.
    Oncogene; 2001 Sep 20; 20(42):6009-17. PubMed ID: 11593408
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  • 18. Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors.
    Liu JC, Deng T, Lehal RS, Kim J, Zacksenhaus E.
    Cancer Res; 2007 Sep 15; 67(18):8671-81. PubMed ID: 17875707
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  • 19. The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis.
    Rudolph-Owen LA, Chan R, Muller WJ, Matrisian LM.
    Cancer Res; 1998 Dec 01; 58(23):5500-6. PubMed ID: 9850086
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  • 20. Farnesyltransferase inhibitors and human malignant pleural mesothelioma: a first-step comparative translational study.
    Cesario A, Catassi A, Festi L, Imperatori A, Pericelli A, Galetta D, Margaritora S, Porziella V, Cardaci V, Granone P, Dominioni L, Russo P.
    Clin Cancer Res; 2005 Mar 01; 11(5):2026-37. PubMed ID: 15756029
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