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Journal Abstract Search

870 related items for PubMed ID: 9918922

  • 21. Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection.
    Ghosh J, Das J, Manna P, Sil PC.
    Free Radic Biol Med; 2010 Feb 15; 48(4):535-53. PubMed ID: 19969075
    [Abstract] [Full Text] [Related]

  • 22. Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver.
    Zhao P, Kalhorn TF, Slattery JT.
    Hepatology; 2002 Aug 15; 36(2):326-35. PubMed ID: 12143040
    [Abstract] [Full Text] [Related]

  • 23. Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine.
    Tan SC, New LS, Chan EC.
    Toxicol Lett; 2008 Aug 28; 180(3):174-81. PubMed ID: 18588957
    [Abstract] [Full Text] [Related]

  • 24. Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
    Aubert J, Begriche K, Delannoy M, Morel I, Pajaud J, Ribault C, Lepage S, McGill MR, Lucas-Clerc C, Turlin B, Robin MA, Jaeschke H, Fromenty B.
    J Pharmacol Exp Ther; 2012 Sep 28; 342(3):676-87. PubMed ID: 22647274
    [Abstract] [Full Text] [Related]

  • 25. S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice.
    Valentovic M, Terneus M, Harmon RC, Carpenter AB.
    Toxicol Lett; 2004 Dec 30; 154(3):165-74. PubMed ID: 15501608
    [Abstract] [Full Text] [Related]

  • 26. Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage.
    Abdel-Zaher AO, Abdel-Rahman MM, Hafez MM, Omran FM.
    Toxicology; 2007 May 05; 234(1-2):124-34. PubMed ID: 17391827
    [Abstract] [Full Text] [Related]

  • 27. Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury.
    Lu Y, Zhang C, Chen YH, Wang H, Zhang ZH, Chen X, Xu DX.
    Sci Rep; 2017 Feb 16; 7():42736. PubMed ID: 28205631
    [Abstract] [Full Text] [Related]

  • 28. Protective effect of rosiglitazone against acetaminophen-induced acute liver injury is associated with down-regulation of hepatic NADPH oxidases.
    Wang JX, Zhang C, Fu L, Zhang DG, Wang BW, Zhang ZH, Chen YH, Lu Y, Chen X, Xu DX.
    Toxicol Lett; 2017 Jan 04; 265():38-46. PubMed ID: 27866976
    [Abstract] [Full Text] [Related]

  • 29. Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion.
    Manautou JE, Emeigh Hart SG, Khairallah EA, Cohen SD.
    Fundam Appl Toxicol; 1996 Feb 04; 29(2):229-37. PubMed ID: 8742320
    [Abstract] [Full Text] [Related]

  • 30. Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.
    Moffit JS, Aleksunes LM, Kardas MJ, Slitt AL, Klaassen CD, Manautou JE.
    Toxicology; 2007 Feb 12; 230(2-3):197-206. PubMed ID: 17188792
    [Abstract] [Full Text] [Related]

  • 31. Diverse antioxidants protect against acetaminophen hepatotoxicity.
    Oz HS, McClain CJ, Nagasawa HT, Ray MB, de Villiers WJ, Chen TS.
    J Biochem Mol Toxicol; 2004 Feb 12; 18(6):361-8. PubMed ID: 15674847
    [Abstract] [Full Text] [Related]

  • 32. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts.
    Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1996 Sep 12; 140(1):30-8. PubMed ID: 8806867
    [Abstract] [Full Text] [Related]

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  • 35. Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.
    Chen C, Krausz KW, Shah YM, Idle JR, Gonzalez FJ.
    Chem Res Toxicol; 2009 Apr 12; 22(4):699-707. PubMed ID: 19256530
    [Abstract] [Full Text] [Related]

  • 36. Osthole prevents acetaminophen-induced liver injury in mice.
    Cai Y, Sun W, Zhang XX, Lin YD, Chen H, Li H.
    Acta Pharmacol Sin; 2018 Jan 12; 39(1):74-84. PubMed ID: 29022574
    [Abstract] [Full Text] [Related]

  • 37. Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice.
    McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, Chatterton-Kirchmeier S, White CC, Pierce RH, Kavanagh TJ.
    Toxicol Sci; 2007 Oct 12; 99(2):628-36. PubMed ID: 17584759
    [Abstract] [Full Text] [Related]

  • 38. Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice.
    Srinivasan C, Williams WM, Ray MB, Chen TS.
    Biochem Pharmacol; 2001 Jan 15; 61(2):245-52. PubMed ID: 11163339
    [Abstract] [Full Text] [Related]

  • 39. Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways.
    Wang Y, Jiang Y, Fan X, Tan H, Zeng H, Wang Y, Chen P, Huang M, Bi H.
    Toxicol Lett; 2015 Jul 16; 236(2):82-9. PubMed ID: 25956474
    [Abstract] [Full Text] [Related]

  • 40. Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.
    Jiang Y, Fan X, Wang Y, Chen P, Zeng H, Tan H, Gonzalez FJ, Huang M, Bi H.
    Toxicol Sci; 2015 Jan 16; 143(1):107-15. PubMed ID: 25319358
    [Abstract] [Full Text] [Related]

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