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164 related items for PubMed ID: 9923545

  • 21. O6-alkylguanine DNA-alkyltransferase is not a major determinant of sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea in four medulloblastoma cell lines.
    Silber JR, Bobola MS, Ewers TG, Muramoto M, Berger MS.
    Oncol Res; 1992; 4(6):241-8. PubMed ID: 1421617
    [Abstract] [Full Text] [Related]

  • 22. Repair analysis of 4-hydroperoxycyclophosphamide-induced DNA interstrand crosslinking in the c-myc gene in 4-hydroperoxycyclophosphamide-sensitive and -resistant medulloblastoma cell lines.
    Dong Q, Bullock N, Ali-Osman F, Colvin OM, Bigner DD, Friedman HS.
    Cancer Chemother Pharmacol; 1996; 37(3):242-46. PubMed ID: 8529284
    [Abstract] [Full Text] [Related]

  • 23. Enhancement of platinum-induced cytotoxicity by O6-benzylguanine.
    Fishel ML, Delaney SM, Friesen LD, Hansen RJ, Zuhowski EG, Moschel RC, Egorin MJ, Dolan ME.
    Mol Cancer Ther; 2003 Jul; 2(7):633-40. PubMed ID: 12883036
    [Abstract] [Full Text] [Related]

  • 24. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
    Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME.
    J Pharmacol Exp Ther; 2005 Dec; 315(3):1247-55. PubMed ID: 16126841
    [Abstract] [Full Text] [Related]

  • 25. Conserved residue lysine165 is essential for the ability of O6-alkylguanine-DNA alkyltransferase to react with O6-benzylguanine.
    Xu-Welliver M, Kanugula S, Loktionova NA, Crone TM, Pegg AE.
    Biochem J; 2000 Apr 15; 347(Pt 2):527-34. PubMed ID: 10749683
    [Abstract] [Full Text] [Related]

  • 26. Role of codon 160 in the sensitivity of human O6-alkylguanine-DNA alkyltransferase to O6-benzylguanine.
    Xu-Welliver M, Leitão J, Kanugula S, Meehan WJ, Pegg AE.
    Biochem Pharmacol; 1999 Oct 15; 58(8):1279-85. PubMed ID: 10487529
    [Abstract] [Full Text] [Related]

  • 27. Determination of the optimal modulatory dose of O6-benzylguanine in patients with surgically resectable tumors.
    Dolan ME, Posner M, Karrison T, Radosta J, Steinberg G, Bertucci D, Vujasin L, Ratain MJ.
    Clin Cancer Res; 2002 Aug 15; 8(8):2519-23. PubMed ID: 12171878
    [Abstract] [Full Text] [Related]

  • 28. O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU.
    Wedge SR, Newlands ES.
    Br J Cancer; 1996 May 15; 73(9):1049-52. PubMed ID: 8624262
    [Abstract] [Full Text] [Related]

  • 29. Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model.
    Wedge SR, Porteous JK, Newlands ES.
    Cancer Chemother Pharmacol; 1997 May 15; 40(3):266-72. PubMed ID: 9219512
    [Abstract] [Full Text] [Related]

  • 30. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Kokkinakis DM, Ahmed MM, Delgado R, Fruitwala MM, Mohiuddin M, Albores-Saavedra J.
    Cancer Res; 1997 Dec 01; 57(23):5360-8. PubMed ID: 9393761
    [Abstract] [Full Text] [Related]

  • 31. Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice.
    Ewesuedo RB, Wilson LR, Friedman HS, Moschel RC, Dolan ME.
    Cancer Chemother Pharmacol; 2001 Dec 01; 47(1):63-9. PubMed ID: 11221964
    [Abstract] [Full Text] [Related]

  • 32. Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
    Gajewski TF, Sosman J, Gerson SL, Liu L, Dolan E, Lin S, Vokes EE.
    Clin Cancer Res; 2005 Nov 01; 11(21):7861-5. PubMed ID: 16278409
    [Abstract] [Full Text] [Related]

  • 33. Potentiation of BCNU anticancer activity by O6-benzylguanine: a study in vitro and in vivo.
    Wan Y, Wu D, Gao H, Lu H.
    J Environ Pathol Toxicol Oncol; 2000 Nov 01; 19(1-2):69-75. PubMed ID: 10905510
    [Abstract] [Full Text] [Related]

  • 34.
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  • 35. Depletion of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine in three-dimensional collagen cultures of normal human breast epithelial cells.
    Hamdan MA, Guzman RC, Yang J, Beattie C, Mascharack P, Nandi S.
    Carcinogenesis; 1992 Oct 01; 13(10):1743-9. PubMed ID: 1423833
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  • 37. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Dolan ME, Stine L, Mitchell RB, Moschel RC, Pegg AE.
    Cancer Commun; 1990 Oct 01; 2(11):371-7. PubMed ID: 2242301
    [Abstract] [Full Text] [Related]

  • 38. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM, Moschel RC, Chae MY, McLaughlin PJ, Zagon IS, Pegg AE.
    Cancer Res; 1995 Sep 15; 55(18):4085-91. PubMed ID: 7664284
    [Abstract] [Full Text] [Related]

  • 39. Acquired resistance to O6-benzylguanine plus chloroethylnitrosoureas in human breast cancer.
    Phillips WP, Gerson SL.
    Cancer Chemother Pharmacol; 1999 Sep 15; 44(4):319-26. PubMed ID: 10447580
    [Abstract] [Full Text] [Related]

  • 40. Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
    Bibby MC, Thompson MJ, Rafferty JA, Margison GP, McElhinney RS.
    Br J Cancer; 1999 Mar 15; 79(9-10):1332-9. PubMed ID: 10188873
    [Abstract] [Full Text] [Related]

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