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Journal Abstract Search

840 related items for PubMed ID: 9923679

  • 1. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.
    Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M.
    Nature; 1999 Jan 14; 397(6715):164-8. PubMed ID: 9923679
    [Abstract] [Full Text] [Related]

  • 2. The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression.
    Vonlanthen S, Heighway J, Altermatt HJ, Gugger M, Kappeler A, Borner MM, van Lohuizen M, Betticher DC.
    Br J Cancer; 2001 May 18; 84(10):1372-6. PubMed ID: 11355949
    [Abstract] [Full Text] [Related]

  • 3. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.
    Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M.
    Genes Dev; 1999 Oct 15; 13(20):2678-90. PubMed ID: 10541554
    [Abstract] [Full Text] [Related]

  • 4. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.
    Pardal R, Molofsky AV, He S, Morrison SJ.
    Cold Spring Harb Symp Quant Biol; 2005 Oct 15; 70():177-85. PubMed ID: 16869752
    [Abstract] [Full Text] [Related]

  • 5. Contribution of p16(INK4a) to replicative senescence of human fibroblasts.
    Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J, Peters G.
    Exp Cell Res; 2004 Aug 15; 298(2):549-59. PubMed ID: 15265701
    [Abstract] [Full Text] [Related]

  • 6. Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a).
    Guney I, Wu S, Sedivy JM.
    Proc Natl Acad Sci U S A; 2006 Mar 07; 103(10):3645-50. PubMed ID: 16537449
    [Abstract] [Full Text] [Related]

  • 7. Bmi-1 reduction plays a key role in physiological and premature aging of primary human keratinocytes.
    Cordisco S, Maurelli R, Bondanza S, Stefanini M, Zambruno G, Guerra L, Dellambra E.
    J Invest Dermatol; 2010 Apr 07; 130(4):1048-62. PubMed ID: 19907431
    [Abstract] [Full Text] [Related]

  • 8. Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF.
    Kranc KR, Bamforth SD, Bragança J, Norbury C, van Lohuizen M, Bhattacharya S.
    Mol Cell Biol; 2003 Nov 07; 23(21):7658-66. PubMed ID: 14560011
    [Abstract] [Full Text] [Related]

  • 9. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.
    Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R.
    Genes Dev; 2005 Jun 15; 19(12):1432-7. PubMed ID: 15964994
    [Abstract] [Full Text] [Related]

  • 10. Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.
    Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, van Welsem T, van de Vijver MJ, Koh EY, Daley GQ, van Lohuizen M.
    Nat Genet; 2000 Nov 15; 26(3):291-9. PubMed ID: 11062467
    [Abstract] [Full Text] [Related]

  • 11. Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas.
    Silva J, García JM, Peña C, García V, Domínguez G, Suárez D, Camacho FI, Espinosa R, Provencio M, España P, Bonilla F.
    Clin Cancer Res; 2006 Dec 01; 12(23):6929-36. PubMed ID: 17145810
    [Abstract] [Full Text] [Related]

  • 12. BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.
    Beà S, Tort F, Pinyol M, Puig X, Hernández L, Hernández S, Fernandez PL, van Lohuizen M, Colomer D, Campo E.
    Cancer Res; 2001 Mar 15; 61(6):2409-12. PubMed ID: 11289106
    [Abstract] [Full Text] [Related]

  • 13. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.
    Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP.
    Mol Cell Biol; 2003 Jan 15; 23(1):389-401. PubMed ID: 12482990
    [Abstract] [Full Text] [Related]

  • 14. Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins.
    Guo WJ, Datta S, Band V, Dimri GP.
    Mol Biol Cell; 2007 Feb 15; 18(2):536-46. PubMed ID: 17151361
    [Abstract] [Full Text] [Related]

  • 15. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.
    Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K, Tanger E, Hulsman D, Leung C, Arsenijevic Y, Marino S, van Lohuizen M.
    Genes Dev; 2005 Jun 15; 19(12):1438-43. PubMed ID: 15964995
    [Abstract] [Full Text] [Related]

  • 16. Bmi1, stem cells, and senescence regulation.
    Park IK, Morrison SJ, Clarke MF.
    J Clin Invest; 2004 Jan 15; 113(2):175-9. PubMed ID: 14722607
    [Abstract] [Full Text] [Related]

  • 17. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras.
    Tremain R, Marko M, Kinnimulki V, Ueno H, Bottinger E, Glick A.
    Oncogene; 2000 Mar 23; 19(13):1698-709. PubMed ID: 10763827
    [Abstract] [Full Text] [Related]

  • 18. P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency.
    Jin J, Tao J, Gu X, Yu Z, Wang R, Zuo G, Li Q, Lv X, Miao D.
    Sci Rep; 2017 Aug 08; 7(1):7502. PubMed ID: 28790310
    [Abstract] [Full Text] [Related]

  • 19. Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.
    Dietrich N, Bracken AP, Trinh E, Schjerling CK, Koseki H, Rappsilber J, Helin K, Hansen KH.
    EMBO J; 2007 Mar 21; 26(6):1637-48. PubMed ID: 17332741
    [Abstract] [Full Text] [Related]

  • 20. Expression of the p16(INK4a) gene product, methylation of the p16(INK4a) promoter region and expression of the polycomb-group gene BMI-1 in squamous cell lung carcinoma and premalignant endobronchial lesions.
    Breuer RH, Snijders PJ, Sutedja GT, Sewalt RG, Otte AP, Postmus PE, Meijer CJ, Raaphorst FM, Smit EF.
    Lung Cancer; 2005 Jun 21; 48(3):299-306. PubMed ID: 15892997
    [Abstract] [Full Text] [Related]

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