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Journal Abstract Search

128 related items for PubMed ID: 9925295

  • 1. Preparation and biological activity of novel tricyclic GPIIb/IIIa antagonists.
    Robarge KD, Dina MS, Somers TC, Lee A, Rawson TE, Olivero AG, Tischler MH, Webb RR, Weese KJ, Aliagas I, Blackburn BK.
    Bioorg Med Chem; 1998 Dec; 6(12):2345-81. PubMed ID: 9925295
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  • 2. Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists.
    Sall DJ, Arfsten AE, Bastian JA, Denney ML, Harms CS, McCowan JR, Morin JM, Rose JW, Scarborough RM, Smyth MS, Um SL, Utterback BG, Vasileff RT, Wikel JH, Wyss VL, Jakubowski JA.
    J Med Chem; 1997 Aug 29; 40(18):2843-57. PubMed ID: 9288166
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  • 3. New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
    Badorc A, Bordes MF, de Cointet P, Savi P, Bernat A, Lalé A, Petitou M, Maffrand JP, Herbert JM.
    J Med Chem; 1997 Oct 10; 40(21):3393-401. PubMed ID: 9341914
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  • 4. From peptide to non-peptide. 3. Atropisomeric GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus.
    Blackburn BK, Lee A, Baier M, Kohl B, Olivero AG, Matamoros R, Robarge KD, McDowell RS.
    J Med Chem; 1997 Feb 28; 40(5):717-29. PubMed ID: 9057858
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  • 5. Discovery and structure--activity relationship studies of a novel and specific peptide motif, Pro-X-X-X-Asp-X, as a platelet fibrinogen receptor antagonist.
    Hayashi Y, Katada J, Sato Y, Igarashi K, Takiguchi Y, Harada T, Muramatsu M, Yasuda E, Uno I.
    Bioorg Med Chem; 1998 Mar 28; 6(3):355-64. PubMed ID: 9568289
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  • 6. Antagonism of the GPIIb/IIIa receptor with the nonpeptidic molecule BIBU52: inhibition of platelet aggregation in vitro and antithrombotic efficacy in vivo.
    Guth BD, Seewaldt-Becker E, Himmelsbach F, Weisenberger H, Müller TH.
    J Cardiovasc Pharmacol; 1997 Aug 28; 30(2):261-72. PubMed ID: 9269956
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  • 7. Design and synthesis of an orally active GPIIb/IIIa antagonist based on a phenylpiperazine scaffold.
    van Maarseveen JH, den Hartog JA, Tipker K, Reinders JH, Brakkee J, Schön U, Kehrbach W, Kruse CG.
    Bioorg Med Chem Lett; 1998 Jun 16; 8(12):1531-6. PubMed ID: 9873384
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  • 15. Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets.
    Schwarz M, Meade G, Stoll P, Ylanne J, Bassler N, Chen YC, Hagemeyer CE, Ahrens I, Moran N, Kenny D, Fitzgerald D, Bode C, Peter K.
    Circ Res; 2006 Jul 07; 99(1):25-33. PubMed ID: 16778135
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  • 16. Thromboxane A(2) synthase inhibitor enhanced antithrombotic efficacy of GPIIb-IIIa receptor antagonist without increasing bleeding.
    Kawano KI, Hokamura K, Kondo K, Ikeda Y, Suzuki Y, Umemura K.
    Eur J Pharmacol; 2001 Apr 13; 417(3):217-22. PubMed ID: 11334853
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  • 17. Design, synthesis and evaluation of 1,4-benzodioxine derivatives as novel platelet aggregation inhibitors.
    Xie Z, Zhao L, Ding X, Kong Y, Li Z.
    Future Med Chem; 2018 Feb 13; 10(4):367-378. PubMed ID: 29380625
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  • 18. Novel non-peptide fibrinogen receptor antagonists. 1. Synthesis and glycoprotein IIb-IIIa antagonistic activities of 1,3,4-trisubstituted 2-oxopiperazine derivatives incorporating side-chain functions of the RGDF peptide.
    Sugihara H, Fukushi H, Miyawaki T, Imai Y, Terashita Z, Kawamura M, Fujisawa Y, Kita S.
    J Med Chem; 1998 Feb 12; 41(4):489-502. PubMed ID: 9484499
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  • 19. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative.
    Yuk DY, Ryu CK, Hong JT, Chung KH, Kang WS, Kim Y, Yoo HS, Lee MK, Lee CK, Yun YP.
    Biochem Pharmacol; 2000 Oct 01; 60(7):1001-8. PubMed ID: 10974210
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