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Journal Abstract Search

540 related items for PubMed ID: 9931032

  • 1.
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  • 2. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
    Hans M, Hornung A, Dziarnowski A, Cane DE, Khosla C.
    J Am Chem Soc; 2003 May 07; 125(18):5366-74. PubMed ID: 12720450
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  • 4. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P, Koppisch AT, Cane DE, Khosla C.
    J Am Chem Soc; 2003 Nov 26; 125(47):14307-12. PubMed ID: 14624579
    [Abstract] [Full Text] [Related]

  • 5. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C.
    Biochemistry; 2004 Nov 09; 43(44):13892-8. PubMed ID: 15518537
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  • 6. Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase.
    Kao CM, Pieper R, Cane DE, Khosla C.
    Biochemistry; 1996 Sep 24; 35(38):12363-8. PubMed ID: 8823171
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  • 7. Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase.
    Pieper R, Gokhale RS, Luo G, Cane DE, Khosla C.
    Biochemistry; 1997 Feb 18; 36(7):1846-51. PubMed ID: 9048569
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  • 8. A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.
    Reid R, Piagentini M, Rodriguez E, Ashley G, Viswanathan N, Carney J, Santi DV, Hutchinson CR, McDaniel R.
    Biochemistry; 2003 Jan 14; 42(1):72-9. PubMed ID: 12515540
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  • 9. Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis.
    Jacobsen JR, Cane DE, Khosla C.
    Biochemistry; 1998 Apr 07; 37(14):4928-34. PubMed ID: 9538011
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  • 10.
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  • 11. Origin of starter units for erythromycin biosynthesis.
    Weissman KJ, Bycroft M, Staunton J, Leadlay PF.
    Biochemistry; 1998 Aug 04; 37(31):11012-7. PubMed ID: 9692995
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  • 12. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y, Lee TS, Kobayashi S, Khosla C.
    Biochemistry; 2003 Jun 03; 42(21):6588-95. PubMed ID: 12767243
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  • 13. The molecular basis of Celmer's rules: the stereochemistry of the condensation step in chain extension on the erythromycin polyketide synthase.
    Weissman KJ, Timoney M, Bycroft M, Grice P, Hanefeld U, Staunton J, Leadlay PF.
    Biochemistry; 1997 Nov 11; 36(45):13849-55. PubMed ID: 9374862
    [Abstract] [Full Text] [Related]

  • 14. Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.
    Reeves CD, Murli S, Ashley GW, Piagentini M, Hutchinson CR, McDaniel R.
    Biochemistry; 2001 Dec 25; 40(51):15464-70. PubMed ID: 11747421
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  • 15. Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase.
    Petković H, Sandmann A, Challis IR, Hecht HJ, Silakowski B, Low L, Beeston N, Kuscer E, Garcia-Bernardo J, Leadlay PF, Kendrew SG, Wilkinson B, Müller R.
    Org Biomol Chem; 2008 Feb 07; 6(3):500-6. PubMed ID: 18219420
    [Abstract] [Full Text] [Related]

  • 16. 6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering.
    Kennedy J, Murli S, Kealey JT.
    Biochemistry; 2003 Dec 09; 42(48):14342-8. PubMed ID: 14640703
    [Abstract] [Full Text] [Related]

  • 17. 6-deoxyerythronolide B synthase 1 is specifically acylated by a diketide intermediate at the beta-ketoacyl-acyl carrier protein synthase domain of module 2.
    Tsukamoto N, Chuck JA, Luo G, Kao CM, Khosla C, Cane DE.
    Biochemistry; 1996 Dec 03; 35(48):15244-8. PubMed ID: 8952473
    [Abstract] [Full Text] [Related]

  • 18. Molecular basis of Celmer's rules: the role of two ketoreductase domains in the control of chirality by the erythromycin modular polyketide synthase.
    Holzbaur IE, Harris RC, Bycroft M, Cortes J, Bisang C, Staunton J, Rudd BA, Leadlay PF.
    Chem Biol; 1999 Apr 03; 6(4):189-95. PubMed ID: 10099131
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