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Journal Abstract Search

203 related items for PubMed ID: 9934846

  • 1. Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators.
    Rose ML, Rivera CA, Bradford BU, Graves LM, Cattley RC, Schoonhoven R, Swenberg JA, Thurman RG.
    Carcinogenesis; 1999 Jan; 20(1):27-33. PubMed ID: 9934846
    [Abstract] [Full Text] [Related]

  • 2. Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.
    Rusyn I, Yamashina S, Segal BH, Schoonhoven R, Holland SM, Cattley RC, Swenberg JA, Thurman RG.
    Cancer Res; 2000 Sep 01; 60(17):4798-803. PubMed ID: 10987289
    [Abstract] [Full Text] [Related]

  • 3. Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643.
    Rose ML, Germolec D, Arteel GE, Schoonhoven R, Thurman RG.
    Chem Res Toxicol; 1997 Oct 01; 10(10):1198-204. PubMed ID: 9348444
    [Abstract] [Full Text] [Related]

  • 4. WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes.
    Rusyn I, Tsukamoto H, Thurman RG.
    Carcinogenesis; 1998 Jul 01; 19(7):1217-22. PubMed ID: 9683180
    [Abstract] [Full Text] [Related]

  • 5. Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells.
    Rusyn I, Kadiiska MB, Dikalova A, Kono H, Yin M, Tsuchiya K, Mason RP, Peters JM, Gonzalez FJ, Segal BH, Holland SM, Thurman RG.
    Mol Pharmacol; 2001 Apr 01; 59(4):744-50. PubMed ID: 11259618
    [Abstract] [Full Text] [Related]

  • 6. Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators.
    Rusyn I, Rose ML, Bojes HK, Thurman RG.
    Antioxid Redox Signal; 2000 Apr 01; 2(3):607-21. PubMed ID: 11229371
    [Abstract] [Full Text] [Related]

  • 7. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
    Woods CG, Burns AM, Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, Peters JM, Rusyn I.
    Free Radic Biol Med; 2007 Feb 01; 42(3):335-42. PubMed ID: 17210446
    [Abstract] [Full Text] [Related]

  • 8. Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators.
    Rose ML, Germolec DR, Schoonhoven R, Thurman RG.
    Carcinogenesis; 1997 Aug 01; 18(8):1453-6. PubMed ID: 9276615
    [Abstract] [Full Text] [Related]

  • 9. Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.
    Peters JM, Rusyn I, Rose ML, Gonzalez FJ, Thurman RG.
    Carcinogenesis; 2000 Apr 01; 21(4):823-6. PubMed ID: 10753222
    [Abstract] [Full Text] [Related]

  • 10. Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.
    Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I.
    Toxicol Appl Pharmacol; 2007 Dec 15; 225(3):267-77. PubMed ID: 17950772
    [Abstract] [Full Text] [Related]

  • 11. Role of Kupffer cells and oxidants in signaling peroxisome proliferator-induced hepatocyte proliferation.
    Rose ML, Rusyn I, Bojes HK, Belyea J, Cattley RC, Thurman RG.
    Mutat Res; 2000 Mar 17; 448(2):179-92. PubMed ID: 10725471
    [No Abstract] [Full Text] [Related]

  • 12. Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643.
    Rose ML, Cattley RC, Dunn C, Wong V, Li X, Thurman RG.
    Carcinogenesis; 1999 Nov 17; 20(11):2075-81. PubMed ID: 10545408
    [Abstract] [Full Text] [Related]

  • 13. Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms.
    Rusyn I, Bradham CA, Cohn L, Schoonhoven R, Swenberg JA, Brenner DA, Thurman RG.
    Carcinogenesis; 1999 Nov 17; 20(11):2095-100. PubMed ID: 10545411
    [Abstract] [Full Text] [Related]

  • 14. Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes.
    Parzefall W, Berger W, Kainzbauer E, Teufelhofer O, Schulte-Hermann R, Thurman RG.
    Carcinogenesis; 2001 Mar 17; 22(3):519-23. PubMed ID: 11238195
    [Abstract] [Full Text] [Related]

  • 15. Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643.
    Conway JG, Tomaszewski KE, Olson MJ, Cattley RC, Marsman DS, Popp JA.
    Carcinogenesis; 1989 Mar 17; 10(3):513-9. PubMed ID: 2924396
    [Abstract] [Full Text] [Related]

  • 16. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.
    Marsman DS, Cattley RC, Conway JG, Popp JA.
    Cancer Res; 1988 Dec 01; 48(23):6739-44. PubMed ID: 3180084
    [Abstract] [Full Text] [Related]

  • 17. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
    Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I.
    Toxicol Sci; 2007 Aug 01; 98(2):366-74. PubMed ID: 17483499
    [Abstract] [Full Text] [Related]

  • 18. Peroxisome proliferators activate Kupffer cells in vivo.
    Bojes HK, Thurman RG.
    Cancer Res; 1996 Jan 01; 56(1):1-4. PubMed ID: 8548746
    [Abstract] [Full Text] [Related]

  • 19. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?
    Melnick RL.
    Environ Health Perspect; 2001 May 01; 109(5):437-42. PubMed ID: 11401753
    [Abstract] [Full Text] [Related]

  • 20. Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells.
    Tsutsui T, Watanabe E, Barrett JC.
    Carcinogenesis; 1993 Apr 01; 14(4):611-8. PubMed ID: 8472324
    [Abstract] [Full Text] [Related]

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