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Journal Abstract Search

129 related items for PubMed ID: 9971915

  • 1. N-terminal 4-imidazolidinone prodrugs of Leu-enkephalin: synthesis, chemical and enzymatic stability studies.
    Bak A, Fich M, Larsen BD, Frokjaer S, Friis GJ.
    Eur J Pharm Sci; 1999 Mar; 7(4):317-23. PubMed ID: 9971915
    [Abstract] [Full Text] [Related]

  • 2. Further characterization of the in vitro hydrolysis of [Leu]- and [Met]enkephalin in rat plasma: HPLC-ECD measurement of substrate and metabolite concentrations.
    Shibanoki S, Weinberger SB, Ishikawa K, Martinez JL.
    Regul Pept; 1991 Feb 26; 32(3):267-78. PubMed ID: 1678195
    [Abstract] [Full Text] [Related]

  • 3. Characterization of hydrolysis of [leu]enkephalin and D-ala2-[L-leu]enkephalin in rat plasma.
    Weinberger SB, Martinez JL.
    J Pharmacol Exp Ther; 1988 Oct 26; 247(1):129-35. PubMed ID: 2902210
    [Abstract] [Full Text] [Related]

  • 4. Enkephalin hydrolysis by mouse plasma in vitro.
    Shibanoki S, Weinberger SB, Schulteis G, Ishikawa K, Martinez JL.
    Life Sci; 1992 Oct 26; 50(10):667-75. PubMed ID: 1346713
    [Abstract] [Full Text] [Related]

  • 5. Chemical and enzymatic stability as well as transport properties of a Leu-enkephalin analogue and ester prodrugs thereof.
    Fredholt K, Adrian C, Just L, Hoj Larsen D, Weng S, Moss B, Juel Friis G.
    J Control Release; 2000 Feb 03; 63(3):261-73. PubMed ID: 10601722
    [Abstract] [Full Text] [Related]

  • 6. Phenylpropionic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeation.
    Gudmundsson OS, Nimkar K, Gangwar S, Siahaan T, Borchardt RT.
    Pharm Res; 1999 Jan 03; 16(1):16-23. PubMed ID: 9950273
    [Abstract] [Full Text] [Related]

  • 7. Optimizing oral absorption of peptides using prodrug strategies.
    Borchardt RT.
    J Control Release; 1999 Nov 01; 62(1-2):231-8. PubMed ID: 10518655
    [Abstract] [Full Text] [Related]

  • 8. Opioid activity of 4-imidazolidinone positional analogues of Leu-Enkephalin.
    Rinnová M, Nefzi A, Houghten RA.
    Bioorg Med Chem Lett; 2002 Nov 04; 12(21):3175-8. PubMed ID: 12372527
    [Abstract] [Full Text] [Related]

  • 9. High enkephalyl peptide degradation, due to angiotensin-converting enzyme-like activity in human CSF.
    Lantz I, Terenius L.
    FEBS Lett; 1985 Nov 25; 193(1):31-4. PubMed ID: 2998876
    [Abstract] [Full Text] [Related]

  • 10. The effect of glycation on the chemical and enzymatic stability of the endogenous opioid peptide, leucine-enkephalin, and related fragments.
    Jakas A, Horvat S.
    Bioorg Chem; 2004 Dec 25; 32(6):516-26. PubMed ID: 15530992
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers.
    Wang B, Nimkar K, Wang W, Zhang H, Shan D, Gudmundsson O, Gangwar S, Siahaan T, Borchardt RT.
    J Pept Res; 1999 Apr 25; 53(4):370-82. PubMed ID: 10406215
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker.
    Bak A, Siahaan TJ, Gudmundsson OS, Gangwar S, Friis GJ, Borchardt RT.
    J Pept Res; 1999 Apr 25; 53(4):393-402. PubMed ID: 10406217
    [Abstract] [Full Text] [Related]

  • 13. Kinetics of degradation of 4-imidazolidinone prodrug types obtained from reacting prilocaine with formaldehyde and acetaldehyde.
    Larsen SW, Sidenius M, Ankersen M, Larsen C.
    Eur J Pharm Sci; 2003 Oct 25; 20(2):233-40. PubMed ID: 14550890
    [Abstract] [Full Text] [Related]

  • 14. Hydrolysis of [Leu]enkephalin by chick brain in vitro.
    Shibanoki S, Weinberger SB, Beniston D, Schulteis G, Bennett EL, Rosenzweig MR, Ishikawa K, Martinez JL.
    Comp Biochem Physiol B; 1991 Oct 25; 99(2):301-6. PubMed ID: 1684927
    [Abstract] [Full Text] [Related]

  • 15. Degradation of low-molecular-weight opioid peptides by vascular plasma membrane aminopeptidase M.
    Bausback HH, Ward PE.
    Biochim Biophys Acta; 1986 Jul 16; 882(3):437-44. PubMed ID: 2873842
    [Abstract] [Full Text] [Related]

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  • 17. Enkephalin analog prodrugs: assessment of in vitro conversion, enzyme cleavage characterization and blood-brain barrier permeability.
    Greene DL, Hau VS, Abbruscato TJ, Bartosz H, Misicka A, Lipkowski AW, Hom S, Gillespie TJ, Hruby VJ, Davis TP.
    J Pharmacol Exp Ther; 1996 Jun 16; 277(3):1366-75. PubMed ID: 8667199
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol.
    Kumpulainen H, Järvinen T, Mannila A, Leppänen J, Nevalainen T, Mäntylä A, Vepsäläinen J, Rautio J.
    Eur J Pharm Sci; 2008 Jul 03; 34(2-3):110-7. PubMed ID: 18403185
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, hydrolysis, and intraocular pressure lowering effects of fadolmidine prodrugs.
    Niemi R, Huuskonen J, Laine K, Järvinen T.
    Int J Pharm; 2005 May 13; 295(1-2):121-7. PubMed ID: 15847997
    [Abstract] [Full Text] [Related]

  • 20. Hydrolysis of [Leu]enkephalin by chick plasma in vitro.
    Shibanoki S, Weinberger SB, Beniston D, Nudelman KA, Schulteis G, Bennett EL, Rosenzweig MR, Ishikawa K, Martinez JL.
    J Pharmacol Exp Ther; 1991 Feb 13; 256(2):650-5. PubMed ID: 1994000
    [Abstract] [Full Text] [Related]

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