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377 related items for PubMed ID: 9988764

  • 1. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.
    Denny MF, Kaufman HC, Chan AC, Straus DB.
    J Biol Chem; 1999 Feb 19; 274(8):5146-52. PubMed ID: 9988764
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
    Williams BL, Irvin BJ, Sutor SL, Chini CC, Yacyshyn E, Bubeck Wardenburg J, Dalton M, Chan AC, Abraham RT.
    EMBO J; 1999 Apr 01; 18(7):1832-44. PubMed ID: 10202147
    [Abstract] [Full Text] [Related]

  • 3. Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.
    Denny MF, Patai B, Straus DB.
    Mol Cell Biol; 2000 Feb 01; 20(4):1426-35. PubMed ID: 10648627
    [Abstract] [Full Text] [Related]

  • 4. Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.
    Wong J, Straus D, Chan AC.
    Mol Cell Biol; 1998 May 01; 18(5):2855-66. PubMed ID: 9566904
    [Abstract] [Full Text] [Related]

  • 5. Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk.
    Williams S, Couture C, Gilman J, Jascur T, Deckert M, Altman A, Mustelin T.
    Eur J Biochem; 1997 Apr 01; 245(1):84-90. PubMed ID: 9128727
    [Abstract] [Full Text] [Related]

  • 6. Association between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck. Differential regulation by TcR cross-linking.
    August A, Dupont B.
    J Biol Chem; 1996 Apr 26; 271(17):10054-9. PubMed ID: 8626561
    [Abstract] [Full Text] [Related]

  • 7. A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.
    Nika K, Tautz L, Arimura Y, Vang T, Williams S, Mustelin T.
    J Biol Chem; 2007 Dec 07; 282(49):36000-9. PubMed ID: 17897955
    [Abstract] [Full Text] [Related]

  • 8. The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.
    Li M, Ong SS, Rajwa B, Thieu VT, Geahlen RL, Harrison ML.
    Mol Cell Biol; 2008 Jan 07; 28(2):630-41. PubMed ID: 17998336
    [Abstract] [Full Text] [Related]

  • 9. Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.
    Mège D, Di Bartolo V, Germain V, Tuosto L, Michel F, Acuto O.
    J Biol Chem; 1996 Dec 20; 271(51):32644-52. PubMed ID: 8955094
    [Abstract] [Full Text] [Related]

  • 10. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
    Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
    Cell Commun Signal; 2020 Nov 23; 18(1):183. PubMed ID: 33225946
    [Abstract] [Full Text] [Related]

  • 11. SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction.
    Straus DB, Chan AC, Patai B, Weiss A.
    J Biol Chem; 1996 Apr 26; 271(17):9976-81. PubMed ID: 8626636
    [Abstract] [Full Text] [Related]

  • 12. T-Cell receptor signaling pathway exerts a negative control on thrombin-mediated increase in [Ca2+]i and p38 MAPK activation in Jurkat T cells: implication of the tyrosine kinase p56Lck.
    Maulon L, Guérin S, Ricci JE, Breittmayer DF, Auberger P.
    Blood; 1998 Jun 01; 91(11):4232-41. PubMed ID: 9596671
    [Abstract] [Full Text] [Related]

  • 13. Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells.
    von Willebrand M, Williams S, Tailor P, Mustelin T.
    Cell Signal; 1998 Jun 01; 10(6):407-13. PubMed ID: 9720763
    [Abstract] [Full Text] [Related]

  • 14. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.
    Guntermann C, Alexander DR.
    J Immunol; 2002 May 01; 168(9):4420-9. PubMed ID: 11970985
    [Abstract] [Full Text] [Related]

  • 15. The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant.
    Gupta S, Weiss A, Kumar G, Wang S, Nel A.
    J Biol Chem; 1994 Jun 24; 269(25):17349-57. PubMed ID: 7516337
    [Abstract] [Full Text] [Related]

  • 16. S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes.
    Kabouridis PS, Magee AI, Ley SC.
    EMBO J; 1997 Aug 15; 16(16):4983-98. PubMed ID: 9305640
    [Abstract] [Full Text] [Related]

  • 17. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF, March ME, Ravichandran KS.
    Eur J Immunol; 1998 Aug 15; 28(8):2265-75. PubMed ID: 9710204
    [Abstract] [Full Text] [Related]

  • 18. Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.
    Livolsi A, Busuttil V, Imbert V, Abraham RT, Peyron JF.
    Eur J Biochem; 2001 Mar 15; 268(5):1508-15. PubMed ID: 11231305
    [Abstract] [Full Text] [Related]

  • 19. Phospho-LAT-independent activation of the ras-mitogen-activated protein kinase pathway: a differential recruitment model of TCR partial agonist signaling.
    Chau LA, Madrenas J.
    J Immunol; 1999 Aug 15; 163(4):1853-8. PubMed ID: 10438919
    [Abstract] [Full Text] [Related]

  • 20. A dual participation of ZAP-70 and scr protein tyrosine kinases is required for TCR-induced tyrosine phosphorylation of Sam68 in Jurkat T cells.
    Lang V, Mège D, Semichon M, Gary-Gouy H, Bismuth G.
    Eur J Immunol; 1997 Dec 15; 27(12):3360-7. PubMed ID: 9464824
    [Abstract] [Full Text] [Related]

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