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Journal Abstract Search

192 related items for PubMed ID: 9990034

  • 21.
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  • 22. Caspase-mediated cleavage is not required for the activity of presenilins in amyloidogenesis and NOTCH signaling.
    Brockhaus M, Grünberg J, Röhrig S, Loetscher H, Wittenburg N, Baumeister R, Jacobsen H, Haass C.
    Neuroreport; 1998 May 11; 9(7):1481-6. PubMed ID: 9631452
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  • 23.
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  • 24. Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
    Okochi M, Ishii K, Usami M, Sahara N, Kametani F, Tanaka K, Fraser PE, Ikeda M, Saunders AM, Hendriks L, Shoji SI, Nee LE, Martin JJ, Van Broeckhoven C, St George-Hyslop PH, Roses AD, Mori H.
    FEBS Lett; 1997 Nov 24; 418(1-2):162-6. PubMed ID: 9414118
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  • 27. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.
    LaVoie MJ, Selkoe DJ.
    J Biol Chem; 2003 Sep 05; 278(36):34427-37. PubMed ID: 12826675
    [Abstract] [Full Text] [Related]

  • 28. Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells.
    Nyormoi O, Wang Z, Doan D, Ruiz M, McConkey D, Bar-Eli M.
    Mol Cell Biol; 2001 Aug 05; 21(15):4856-67. PubMed ID: 11438643
    [Abstract] [Full Text] [Related]

  • 29. Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
    Tesco G, Kim TW, Diehlmann A, Beyreuther K, Tanzi RE.
    J Biol Chem; 1998 Dec 18; 273(51):33909-14. PubMed ID: 9852041
    [Abstract] [Full Text] [Related]

  • 30. Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues.
    Seaman JE, Julien O, Lee PS, Rettenmaier TJ, Thomsen ND, Wells JA.
    Cell Death Differ; 2016 Oct 18; 23(10):1717-26. PubMed ID: 27367566
    [Abstract] [Full Text] [Related]

  • 31. Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches.
    Wellington CL, Hayden MR.
    Clin Genet; 2000 Jan 18; 57(1):1-10. PubMed ID: 10733228
    [Abstract] [Full Text] [Related]

  • 32. A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation.
    Hashimoto-Gotoh T, Tsujimura A, Watanabe Y, Iwabe N, Miyata T, Tabira T.
    Gene; 2003 Dec 24; 323():115-23. PubMed ID: 14659884
    [Abstract] [Full Text] [Related]

  • 33. Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2.
    Koeppel MA, McCarthy CC, Moertl E, Jakobi R.
    J Biol Chem; 2004 Dec 17; 279(51):53653-64. PubMed ID: 15471851
    [Abstract] [Full Text] [Related]

  • 34. Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.
    Herrant M, Jacquel A, Marchetti S, Belhacène N, Colosetti P, Luciano F, Auberger P.
    Oncogene; 2004 Oct 14; 23(47):7863-73. PubMed ID: 15378010
    [Abstract] [Full Text] [Related]

  • 35. Proteolytic processing of Alzheimer's disease associated proteins.
    Haass C, Grünberg J, Capell A, Wild-Bode C, Leimer U, Walter J, Yamazaki T, Ihara I, Zweckbronner I, Jakubek C, Baumeister R.
    J Neural Transm Suppl; 1998 Oct 14; 53():159-67. PubMed ID: 9700654
    [Abstract] [Full Text] [Related]

  • 36. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
    da Costa CA, Ancolio K, Checler F.
    Mol Med; 1999 Mar 14; 5(3):160-8. PubMed ID: 10404513
    [Abstract] [Full Text] [Related]

  • 37. N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression.
    Mori M, Nakagami H, Morishita R, Mitsuda N, Yamamoto K, Yoshimura S, Ohkubo N, Sato N, Ogihara T, Kaneda Y.
    Life Sci; 2002 Apr 21; 70(21):2567-80. PubMed ID: 12173418
    [Abstract] [Full Text] [Related]

  • 38. A novel presenilin-2 splice variant in human Alzheimer's disease brain tissue.
    Sato N, Hori O, Yamaguchi A, Lambert JC, Chartier-Harlin MC, Robinson PA, Delacourte A, Schmidt AM, Furuyama T, Imaizumi K, Tohyama M, Takagi T.
    J Neurochem; 1999 Jun 21; 72(6):2498-505. PubMed ID: 10349860
    [Abstract] [Full Text] [Related]

  • 39. The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins.
    Tomita T, Watabiki T, Takikawa R, Morohashi Y, Takasugi N, Kopan R, De Strooper B, Iwatsubo T.
    J Biol Chem; 2001 Aug 31; 276(35):33273-81. PubMed ID: 11432849
    [Abstract] [Full Text] [Related]

  • 40. Nuclear import is required for the pro-apoptotic function of the Golgi protein p115.
    Mukherjee S, Shields D.
    J Biol Chem; 2009 Jan 16; 284(3):1709-17. PubMed ID: 19028683
    [Abstract] [Full Text] [Related]

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