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PUBMED FOR HANDHELDS

Journal Abstract Search


164 related items for PubMed ID: 9990463

  • 1. 2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.
    Imbach P, Capraro HG, Furet P, Mett H, Meyer T, Zimmermann J.
    Bioorg Med Chem Lett; 1999 Jan 04; 9(1):91-6. PubMed ID: 9990463
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  • 2. Synthesis and biological activity of olomoucine II.
    Krystof V, Lenobel R, Havlícek L, Kuzma M, Strnad M.
    Bioorg Med Chem Lett; 2002 Nov 18; 12(22):3283-6. PubMed ID: 12392733
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  • 3. Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.
    Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L.
    Bioorg Med Chem Lett; 1998 Apr 07; 8(7):793-8. PubMed ID: 9871543
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  • 4. 2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors.
    Moravec J, Krystof V, Hanus J, Havlícek L, Moravcová D, Fuksová K, Kuzma M, Lenobel R, Otyepka M, Strnad M.
    Bioorg Med Chem Lett; 2003 Sep 15; 13(18):2993-6. PubMed ID: 12941319
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  • 5. Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors.
    Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L, Giocanti N, Sadri R, Favaudon V.
    Bioorg Med Chem; 1999 Jul 15; 7(7):1281-93. PubMed ID: 10465404
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  • 8. Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.
    Arris CE, Boyle FT, Calvert AH, Curtin NJ, Endicott JA, Garman EF, Gibson AE, Golding BT, Grant S, Griffin RJ, Jewsbury P, Johnson LN, Lawrie AM, Newell DR, Noble ME, Sausville EA, Schultz R, Yu W.
    J Med Chem; 2000 Jul 27; 43(15):2797-804. PubMed ID: 10956187
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  • 11. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.
    Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ, Inagaki N, Inagaki M, Delcros JG, Moulinoux JP.
    Eur J Biochem; 1997 Jan 15; 243(1-2):527-36. PubMed ID: 9030781
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  • 12. N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2.
    Hardcastle IR, Arris CE, Bentley J, Boyle FT, Chen Y, Curtin NJ, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Jewsbury P, Menyerol J, Mesguiche V, Newell DR, Noble ME, Pratt DJ, Wang LZ, Whitfield HJ.
    J Med Chem; 2004 Jul 15; 47(15):3710-22. PubMed ID: 15239650
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  • 13. Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex.
    Legraverend M, Tunnah P, Noble M, Ducrot P, Ludwig O, Grierson DS, Leost M, Meijer L, Endicott J.
    J Med Chem; 2000 Apr 06; 43(7):1282-92. PubMed ID: 10753466
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  • 14. Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors.
    Vandromme L, Piguel S, Lozach O, Meijer L, Legraverend M, Grierson DS.
    Bioorg Med Chem Lett; 2006 Jun 15; 16(12):3144-6. PubMed ID: 16616489
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  • 16. Synthesis and biological evaluation of guanidino analogues of roscovitine.
    Dolečková I, Cesnek M, Dračinský M, Brynda J, Voller J, Janeba Z, Kryštof V.
    Eur J Med Chem; 2013 Apr 15; 62():443-52. PubMed ID: 23399722
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  • 17. 9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.
    Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C.
    J Med Chem; 1997 Jun 06; 40(12):1768-70. PubMed ID: 9191951
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  • 18. Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.
    Moravcová D, Krystof V, Havlícek L, Moravec J, Lenobel R, Strnad M.
    Bioorg Med Chem Lett; 2003 Sep 15; 13(18):2989-92. PubMed ID: 12941318
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  • 20. Synthesis and biological properties of C-2, C-8, N-9 substituted 6-(3-chloroanilino)purine derivatives as cyclin-dependent kinase inhibitors. Part II.
    Oh CH, Kim HK, Lee SC, Oh C, Yang BS, Rhee HJ, Cho JH.
    Arch Pharm (Weinheim); 2001 Nov 15; 334(11):345-50. PubMed ID: 11822171
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