BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 18079963)

  • 1. Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo.
    Sjölund J; Johansson M; Manna S; Norin C; Pietras A; Beckman S; Nilsson E; Ljungberg B; Axelson H
    J Clin Invest; 2008 Jan; 118(1):217-28. PubMed ID: 18079963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.
    Bhagat TD; Zou Y; Huang S; Park J; Palmer MB; Hu C; Li W; Shenoy N; Giricz O; Choudhary G; Yu Y; Ko YA; Izquierdo MC; Park AS; Vallumsetla N; Laurence R; Lopez R; Suzuki M; Pullman J; Kaner J; Gartrell B; Hakimi AA; Greally JM; Patel B; Benhadji K; Pradhan K; Verma A; Susztak K
    J Biol Chem; 2017 Jan; 292(3):837-846. PubMed ID: 27909050
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The alarmin IL-33 is a notch target in quiescent endothelial cells.
    Sundlisaeter E; Edelmann RJ; Hol J; Sponheim J; Küchler AM; Weiss M; Udalova IA; Midwood KS; Kasprzycka M; Haraldsen G
    Am J Pathol; 2012 Sep; 181(3):1099-111. PubMed ID: 22809957
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1.
    Ambler CA; Watt FM
    Development; 2010 Nov; 137(21):3569-79. PubMed ID: 20940224
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VHL mutation drives human clear cell renal cell carcinoma progression through PI3K/AKT-dependent cholesteryl ester accumulation.
    Zhang S; Fang T; He Y; Feng W; Yu Z; Zheng Y; Zhang C; Hu S; Liu Z; Liu J; Yu J; Zhang H; He A; Gong Y; He Z; Yang K; Xi Z; Yu W; Zhou L; Yao L; Yue S
    EBioMedicine; 2024 May; 103():105070. PubMed ID: 38564827
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.
    Buckley NE; Nic An tSaoir CB; Blayney JK; Oram LC; Crawford NT; D'Costa ZC; Quinn JE; Kennedy RD; Harkin DP; Mullan PB
    Nucleic Acids Res; 2013 Oct; 41(18):8601-14. PubMed ID: 23863842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1.
    Yun J; Espinoza I; Pannuti A; Romero D; Martinez L; Caskey M; Stanculescu A; Bocchetta M; Rizzo P; Band V; Band H; Kim HM; Park SK; Kang KW; Avantaggiati ML; Gomez CR; Golde T; Osborne B; Miele L
    J Cell Physiol; 2015 Dec; 230(12):3115-27. PubMed ID: 26033683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The convergence of tumor suppressors on the type I interferon pathway in clear cell renal cell carcinoma and its therapeutic implications.
    Langbein LE; El Hajjar R; Kim WY; Yang H
    Am J Physiol Cell Physiol; 2022 Nov; 323(5):C1417-C1429. PubMed ID: 36154696
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein.
    Rao H; Li X; Liu M; Liu J; Li X; Xu J; Li L; Gao WQ
    Oncogene; 2020 May; 39(19):3853-3866. PubMed ID: 32161311
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of a functional VHL gene product sensitizes renal cell carcinoma cells to the apoptotic effects of the protein synthesis inhibitor verrucarin A.
    Woldemichael GM; Turbyville TJ; Vasselli JR; Linehan WM; McMahon JB
    Neoplasia; 2012 Aug; 14(8):771-7. PubMed ID: 22952429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cholesterol accumulation in ccRCC: the role of ccRCC-initiating VHL-HIFα pathway.
    Mohtar MA; Hasanah Mohd Yusuf SN; Syafruddin SE
    EBioMedicine; 2024 May; 103():105112. PubMed ID: 38599011
    [No Abstract]   [Full Text] [Related]  

  • 12. Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice.
    Fiorotto R; Raizner A; Morell CM; Torsello B; Scirpo R; Fabris L; Spirli C; Strazzabosco M
    J Hepatol; 2013 Jul; 59(1):124-30. PubMed ID: 23500150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages.
    Mandula JK; Sierra-Mondragon RA; Jimenez RV; Chang D; Mohamed E; Chang S; Vazquez-Martinez JA; Cao Y; Anadon CM; Lee SB; Das S; Rocha-Munguba L; Pham VM; Li R; Tarhini AA; Furqan M; Dalton W; Churchman M; Moran-Segura CM; Nguyen J; Perez B; Kojetin DJ; Obermayer A; Yu X; Chen A; Shaw TI; Conejo-Garcia JR; Rodriguez PC
    Immunity; 2024 May; 57(5):1124-1140.e9. PubMed ID: 38636522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool.
    Del Barrio MG; Taveira-Marques R; Muroyama Y; Yuk DI; Li S; Wines-Samuelson M; Shen J; Smith HK; Xiang M; Rowitch D; Richardson WD
    Development; 2007 Oct; 134(19):3427-36. PubMed ID: 17728344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans.
    Ma Y; Joyce A; Brandenburg O; Saatchi F; Stevens C; Toffessi Tcheuyap V; Christie A; Do QN; Fatunde O; Macchiaroli A; Wong SC; Woolford L; Yousuf Q; Miyata J; Carrillo D; Onabolu O; McKenzie T; Mishra A; Hardy T; He W; Li D; Ivanishev A; Zhang Q; Pedrosa I; Kapur P; Schluep T; Kanner SB; Hamilton J; Brugarolas J
    Clin Cancer Res; 2022 Dec; 28(24):5405-5418. PubMed ID: 36190432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma.
    Brugarolas J; Obara G; Beckermann KE; Rini B; Lam ET; Hamilton J; Schluep T; Yi M; Wong S; Mao ZL; Gamelin E; Tannir NM
    Clin Cancer Res; 2024 Jun; 30(11):2402-2411. PubMed ID: 38652038
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.
    Hu L; Zhang Y; Guo L; Zhong H; Xie L; Zhou J; Liao C; Yao H; Fang J; Liu H; Zhang C; Zhang H; Zhu X; Luo M; von Kriegsheim A; Li B; Luo W; Zhang X; Chen X; Mendell JT; Xu L; Kapur P; Baldwin AS; Brugarolas J; Zhang Q
    Mol Cell; 2024 Feb; 84(4):776-790.e5. PubMed ID: 38211588
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The notch and TGF-β signaling pathways contribute to the aggressiveness of clear cell renal cell carcinoma.
    Sjölund J; Boström AK; Lindgren D; Manna S; Moustakas A; Ljungberg B; Johansson M; Fredlund E; Axelson H
    PLoS One; 2011; 6(8):e23057. PubMed ID: 21826227
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.
    Löfstedt T; Fredlund E; Noguera R; Navarro S; Holmquist-Mengelbier L; Beckman S; Påhlman S; Axelson H
    Exp Cell Res; 2009 Jul; 315(11):1924-36. PubMed ID: 19254710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.
    Huang S; Liu J; Hu J; Hou Y; Hu M; Zhang B; Luo H; Fu S; Chen Y; Liu X; Chen Z; Wang L
    J Cell Mol Med; 2024 Apr; 28(8):e18290. PubMed ID: 38588015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.