329 related articles for article (PubMed ID: 19252415)
1. Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells.
Golding SE; Morgan RN; Adams BR; Hawkins AJ; Povirk LF; Valerie K
Cancer Biol Ther; 2009 Apr; 8(8):730-8. PubMed ID: 19252415
[TBL] [Abstract][Full Text] [Related]
2. EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
Mukherjee B; McEllin B; Camacho CV; Tomimatsu N; Sirasanagandala S; Nannepaga S; Hatanpaa KJ; Mickey B; Madden C; Maher E; Boothman DA; Furnari F; Cavenee WK; Bachoo RM; Burma S
Cancer Res; 2009 May; 69(10):4252-9. PubMed ID: 19435898
[TBL] [Abstract][Full Text] [Related]
3. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response.
Golding SE; Rosenberg E; Neill S; Dent P; Povirk LF; Valerie K
Cancer Res; 2007 Feb; 67(3):1046-53. PubMed ID: 17283137
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity.
Lammering G; Hewit TH; Holmes M; Valerie K; Hawkins W; Lin PS; Mikkelsen RB; Schmidt-Ullrich RK
Clin Cancer Res; 2004 Oct; 10(19):6732-43. PubMed ID: 15475464
[TBL] [Abstract][Full Text] [Related]
5. The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining.
Kriegs M; Kasten-Pisula U; Rieckmann T; Holst K; Saker J; Dahm-Daphi J; Dikomey E
DNA Repair (Amst); 2010 Aug; 9(8):889-97. PubMed ID: 20615764
[TBL] [Abstract][Full Text] [Related]
6. Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.
Golding SE; Rosenberg E; Khalil A; McEwen A; Holmes M; Neill S; Povirk LF; Valerie K
J Biol Chem; 2004 Apr; 279(15):15402-10. PubMed ID: 14744854
[TBL] [Abstract][Full Text] [Related]
7. Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants.
Adams BR; Golding SE; Rao RR; Valerie K
PLoS One; 2010 Apr; 5(4):e10001. PubMed ID: 20368801
[TBL] [Abstract][Full Text] [Related]
8. Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells.
Lammering G; Lin PS; Contessa JN; Hampton JL; Valerie K; Schmidt-Ullrich RK
Int J Radiat Oncol Biol Phys; 2001 Nov; 51(3):775-84. PubMed ID: 11697324
[TBL] [Abstract][Full Text] [Related]
9. Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity.
Ye F; Gao Q; Xu T; Zeng L; Ou Y; Mao F; Wang H; He Y; Wang B; Yang Z; Guo D; Lei T
J Neurooncol; 2009 Sep; 94(2):183-94. PubMed ID: 19300910
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation.
Wei F; Yan J; Tang D; Lin X; He L; Xie Y; Tao L; Wang S
Biochim Biophys Acta; 2013 Jan; 1833(1):90-100. PubMed ID: 23098854
[TBL] [Abstract][Full Text] [Related]
11. Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
Nitta Y; Shimizu S; Shishido-Hara Y; Suzuki K; Shiokawa Y; Nagane M
Cancer Med; 2016 Mar; 5(3):486-99. PubMed ID: 26778701
[TBL] [Abstract][Full Text] [Related]
12. Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair.
Kang KB; Zhu C; Wong YL; Gao Q; Ty A; Wong MC
Int J Radiat Oncol Biol Phys; 2012 May; 83(1):e43-52. PubMed ID: 22516386
[TBL] [Abstract][Full Text] [Related]
13. Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells.
Lim YC; Roberts TL; Day BW; Stringer BW; Kozlov S; Fazry S; Bruce ZC; Ensbey KS; Walker DG; Boyd AW; Lavin MF
Mol Oncol; 2014 Dec; 8(8):1603-15. PubMed ID: 25017126
[TBL] [Abstract][Full Text] [Related]
14. ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain.
Yiin JJ; Hu B; Schornack PA; Sengar RS; Liu KW; Feng H; Lieberman FS; Chiou SH; Sarkaria JN; Wiener EC; Ma HI; Cheng SY
Mol Cancer Ther; 2010 Apr; 9(4):929-41. PubMed ID: 20371720
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of FGFR2-Signaling Attenuates a Homology-Mediated DNA Repair in GIST and Sensitizes Them to DNA-Topoisomerase II Inhibitors.
Sergei B; Pavel D; Aigul G; Firyuza B; Ilmira N; Ilshat M; Aida A; Refat K; Natalia A; Elena S; Vera G
Int J Mol Sci; 2020 Jan; 21(1):. PubMed ID: 31948066
[TBL] [Abstract][Full Text] [Related]
16. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity.
Rong Y; Belozerov VE; Tucker-Burden C; Chen G; Durden DL; Olson JJ; Van Meir EG; Mackman N; Brat DJ
Cancer Res; 2009 Mar; 69(6):2540-9. PubMed ID: 19276385
[TBL] [Abstract][Full Text] [Related]
17. Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.
Toulany M; Kehlbach R; Florczak U; Sak A; Wang S; Chen J; Lobrich M; Rodemann HP
Mol Cancer Ther; 2008 Jul; 7(7):1772-81. PubMed ID: 18644989
[TBL] [Abstract][Full Text] [Related]
18. Synergistic anticancer activity of arsenic trioxide with erlotinib is based on inhibition of EGFR-mediated DNA double-strand break repair.
Kryeziu K; Jungwirth U; Hoda MA; Ferk F; Knasmüller S; Karnthaler-Benbakka C; Kowol CR; Berger W; Heffeter P
Mol Cancer Ther; 2013 Jun; 12(6):1073-84. PubMed ID: 23548265
[TBL] [Abstract][Full Text] [Related]
19. K-RAS(V12) induces autocrine production of EGFR ligands and mediates radioresistance through EGFR-dependent Akt signaling and activation of DNA-PKcs.
Minjgee M; Toulany M; Kehlbach R; Giehl K; Rodemann HP
Int J Radiat Oncol Biol Phys; 2011 Dec; 81(5):1506-14. PubMed ID: 21985943
[TBL] [Abstract][Full Text] [Related]
20. T11TS inhibits Angiopoietin-1/Tie-2 signaling, EGFR activation and Raf/MEK/ERK pathway in brain endothelial cells restraining angiogenesis in glioma model.
Bhattacharya D; Chaudhuri S; Singh MK; Chaudhuri S
Exp Mol Pathol; 2015 Jun; 98(3):455-66. PubMed ID: 25797371
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]