407 related articles for article (PubMed ID: 22388088)
1. Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop.
Aceto N; Sausgruber N; Brinkhaus H; Gaidatzis D; Martiny-Baron G; Mazzarol G; Confalonieri S; Quarto M; Hu G; Balwierz PJ; Pachkov M; Elledge SJ; van Nimwegen E; Stadler MB; Bentires-Alj M
Nat Med; 2012 Mar; 18(4):529-37. PubMed ID: 22388088
[TBL] [Abstract][Full Text] [Related]
2. New insights into signalling networks regulating breast cancer stem cells.
Swarbrick A; Daly RJ
Breast Cancer Res; 2012 Sep; 14(5):321. PubMed ID: 22999218
[TBL] [Abstract][Full Text] [Related]
3. Src-homology 2 domain-containing tyrosine phosphatase 2 promotes oral cancer invasion and metastasis.
Wang HC; Chiang WF; Huang HH; Shen YY; Chiang HC
BMC Cancer; 2014 Jun; 14():442. PubMed ID: 24931737
[TBL] [Abstract][Full Text] [Related]
4. A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth.
Patel Y; Shah N; Lee JS; Markoutsa E; Jie C; Liu S; Botbyl R; Reisman D; Xu P; Chen H
Oncotarget; 2016 Apr; 7(14):18295-308. PubMed ID: 26918448
[TBL] [Abstract][Full Text] [Related]
5. CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes.
Niemelä M; Kauko O; Sihto H; Mpindi JP; Nicorici D; Pernilä P; Kallioniemi OP; Joensuu H; Hautaniemi S; Westermarck J
Oncogene; 2012 Sep; 31(39):4266-78. PubMed ID: 22249265
[TBL] [Abstract][Full Text] [Related]
6. SHP2 promotes proliferation of breast cancer cells through regulating Cyclin D1 stability
Yuan Y; Fan Y; Gao Z; Sun X; Zhang H; Wang Z; Cui Y; Song W; Wang Z; Zhang F; Niu R
Cancer Biol Med; 2020 Aug; 17(3):707-725. PubMed ID: 32944401
[No Abstract] [Full Text] [Related]
7. Molecular mechanism for SHP2 in promoting HER2-induced signaling and transformation.
Zhou X; Agazie YM
J Biol Chem; 2009 May; 284(18):12226-34. PubMed ID: 19261604
[TBL] [Abstract][Full Text] [Related]
8. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis.
Zhao H; Martin E; Matalkah F; Shah N; Ivanov A; Ruppert JM; Lockman PR; Agazie YM
Oncogene; 2019 Mar; 38(13):2275-2290. PubMed ID: 30467378
[TBL] [Abstract][Full Text] [Related]
9. A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2).
Hartman Z; Geldenhuys WJ; Agazie YM
J Biol Chem; 2020 Mar; 295(11):3563-3575. PubMed ID: 32024694
[TBL] [Abstract][Full Text] [Related]
10. SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.
Zhang L; Zhang W; Li Y; Alvarez A; Li Z; Wang Y; Song L; Lv D; Nakano I; Hu B; Cheng SY; Feng H
Oncogene; 2016 Oct; 35(43):5641-5652. PubMed ID: 27041571
[TBL] [Abstract][Full Text] [Related]
11. Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition.
Su CM; Lee WH; Wu AT; Lin YK; Wang LS; Wu CH; Yeh CT
J Nutr Biochem; 2015 Jun; 26(6):675-85. PubMed ID: 25792283
[TBL] [Abstract][Full Text] [Related]
12. The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
Aigner K; Dampier B; Descovich L; Mikula M; Sultan A; Schreiber M; Mikulits W; Brabletz T; Strand D; Obrist P; Sommergruber W; Schweifer N; Wernitznig A; Beug H; Foisner R; Eger A
Oncogene; 2007 Oct; 26(49):6979-88. PubMed ID: 17486063
[TBL] [Abstract][Full Text] [Related]
13. Critical role of SHP2 (PTPN11) signaling in germinal center-derived lymphoma.
Jiang X; Guo H; Wu J; He Q; Li Y; Wang M; Pan H; Li W; Wang J; Wang Q; Shen J; Ke Y; Zhou R
Haematologica; 2014 Dec; 99(12):1834-45. PubMed ID: 25193962
[TBL] [Abstract][Full Text] [Related]
14. The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.
Agazie YM; Movilla N; Ischenko I; Hayman MJ
Oncogene; 2003 Oct; 22(44):6909-18. PubMed ID: 14534538
[TBL] [Abstract][Full Text] [Related]
15. SHP2 acts both upstream and downstream of multiple receptor tyrosine kinases to promote basal-like and triple-negative breast cancer.
Matalkah F; Martin E; Zhao H; Agazie YM
Breast Cancer Res; 2016 Jan; 18(1):2. PubMed ID: 26728598
[TBL] [Abstract][Full Text] [Related]
16. Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells.
Hugo HJ; Pereira L; Suryadinata R; Drabsch Y; Gonda TJ; Gunasinghe NP; Pinto C; Soo ET; van Denderen BJ; Hill P; Ramsay RG; Sarcevic B; Newgreen DF; Thompson EW
Breast Cancer Res; 2013 Nov; 15(6):R113. PubMed ID: 24283570
[TBL] [Abstract][Full Text] [Related]
17. Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer.
Werner S; Frey S; Riethdorf S; Schulze C; Alawi M; Kling L; Vafaizadeh V; Sauter G; Terracciano L; Schumacher U; Pantel K; Assmann V
J Biol Chem; 2013 Aug; 288(32):22993-3008. PubMed ID: 23814079
[TBL] [Abstract][Full Text] [Related]
18. Association of nuclear localization of SHP2 and YAP1 with unfavorable prognosis in non-small cell lung cancer.
Chen MJ; Wang YC; Wu DW; Chen CY; Lee H
Pathol Res Pract; 2019 Apr; 215(4):801-806. PubMed ID: 30685130
[TBL] [Abstract][Full Text] [Related]
19. SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer.
Chen H; Libring S; Ruddraraju KV; Miao J; Solorio L; Zhang ZY; Wendt MK
Oncogene; 2020 Dec; 39(49):7166-7180. PubMed ID: 33033382
[TBL] [Abstract][Full Text] [Related]
20. The ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression.
Liu Y; Sánchez-Tilló E; Lu X; Huang L; Clem B; Telang S; Jenson AB; Cuatrecasas M; Chesney J; Postigo A; Dean DC
J Biol Chem; 2014 Feb; 289(7):4116-25. PubMed ID: 24371144
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]