555 related articles for article (PubMed ID: 24841876)
1. Metformin and cancer.
Vallianou NG; Evangelopoulos A; Kazazis C
Rev Diabet Stud; 2013; 10(4):228-35. PubMed ID: 24841876
[TBL] [Abstract][Full Text] [Related]
2. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Shaw RJ; Kosmatka M; Bardeesy N; Hurley RL; Witters LA; DePinho RA; Cantley LC
Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3329-35. PubMed ID: 14985505
[TBL] [Abstract][Full Text] [Related]
3. Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action.
Bang S; Chen Y; Ahima RS; Kim SF
Mol Endocrinol; 2014 Jul; 28(7):1186-93. PubMed ID: 24877601
[TBL] [Abstract][Full Text] [Related]
4. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Huang X; Wullschleger S; Shpiro N; McGuire VA; Sakamoto K; Woods YL; McBurnie W; Fleming S; Alessi DR
Biochem J; 2008 Jun; 412(2):211-21. PubMed ID: 18387000
[TBL] [Abstract][Full Text] [Related]
5. Liver Kinase B1/AMP-Activated Protein Kinase Pathway Activation Attenuated the Progression of Endotoxemia in the Diabetic Mice.
Yang Y; Dong R; Hu D; Chen Z; Fu M; Wang DW; Xu X; Tu L
Cell Physiol Biochem; 2017; 42(2):761-779. PubMed ID: 28628912
[TBL] [Abstract][Full Text] [Related]
6. AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor.
Liu JL; Mao Z; Gallick GE; Yung WK
Neuro Oncol; 2011 Feb; 13(2):184-94. PubMed ID: 21123367
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
Xie Z; Dong Y; Scholz R; Neumann D; Zou MH
Circulation; 2008 Feb; 117(7):952-62. PubMed ID: 18250273
[TBL] [Abstract][Full Text] [Related]
8. LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.
Li NS; Zou JR; Lin H; Ke R; He XL; Xiao L; Huang D; Luo L; Lv N; Luo Z
Tumour Biol; 2016 Jun; 37(6):8249-58. PubMed ID: 26718214
[TBL] [Abstract][Full Text] [Related]
9. Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
Nagalingam A; Arbiser JL; Bonner MY; Saxena NK; Sharma D
Breast Cancer Res; 2012 Feb; 14(1):R35. PubMed ID: 22353783
[TBL] [Abstract][Full Text] [Related]
10. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
Lin CC; Yeh HH; Huang WL; Yan JJ; Lai WW; Su WP; Chen HH; Su WC
Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
[TBL] [Abstract][Full Text] [Related]
11. Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells.
Kawashima I; Mitsumori T; Nozaki Y; Yamamoto T; Shobu-Sueki Y; Nakajima K; Kirito K
Exp Hematol; 2015 Jul; 43(7):524-33.e1. PubMed ID: 25846811
[TBL] [Abstract][Full Text] [Related]
12. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Shaw RJ; Lamia KA; Vasquez D; Koo SH; Bardeesy N; Depinho RA; Montminy M; Cantley LC
Science; 2005 Dec; 310(5754):1642-6. PubMed ID: 16308421
[TBL] [Abstract][Full Text] [Related]
13. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties.
MacDonald AF; Bettaieb A; Donohoe DR; Alani DS; Han A; Zhao Y; Whelan J
BMC Complement Altern Med; 2018 Jun; 18(1):188. PubMed ID: 29914450
[TBL] [Abstract][Full Text] [Related]
14. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Foretz M; Hébrard S; Leclerc J; Zarrinpashneh E; Soty M; Mithieux G; Sakamoto K; Andreelli F; Viollet B
J Clin Invest; 2010 Jul; 120(7):2355-69. PubMed ID: 20577053
[TBL] [Abstract][Full Text] [Related]
15. Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.
Guo Q; Liu Z; Jiang L; Liu M; Ma J; Yang C; Han L; Nan K; Liang X
Mol Med Rep; 2016 Mar; 13(3):2590-6. PubMed ID: 26847819
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation of serine 399 in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation.
Zhu H; Moriasi CM; Zhang M; Zhao Y; Zou MH
J Biol Chem; 2013 Jun; 288(23):16495-16505. PubMed ID: 23612973
[TBL] [Abstract][Full Text] [Related]
17. Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner.
Rattan R; Giri S; Hartmann LC; Shridhar V
J Cell Mol Med; 2011 Jan; 15(1):166-78. PubMed ID: 19874425
[TBL] [Abstract][Full Text] [Related]
18. Berberine Inhibits Gluconeogenesis in Skeletal Muscles and Adipose Tissues in Streptozotocin-induced Diabetic Rats via LKB1-AMPK-TORC2 Signaling Pathway.
Xu XH; Hu Q; Zhou LS; Xu LJ; Zou X; Lu FE; Yi P
Curr Med Sci; 2020 Jun; 40(3):530-538. PubMed ID: 32681256
[TBL] [Abstract][Full Text] [Related]
19. Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.
Ma L; Niknejad N; Gorn-Hondermann I; Dayekh K; Dimitroulakos J
PLoS One; 2012; 7(9):e46055. PubMed ID: 23029387
[TBL] [Abstract][Full Text] [Related]
20. Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.
Algire C; Amrein L; Bazile M; David S; Zakikhani M; Pollak M
Oncogene; 2011 Mar; 30(10):1174-82. PubMed ID: 21102522
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]