296 related articles for article (PubMed ID: 33931647)
1. Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.
Supper E; Rudat S; Iyer V; Droop A; Wong K; Spinella JF; Thomas P; Sauvageau G; Adams DJ; Wong CC
Nat Commun; 2021 Apr; 12(1):2482. PubMed ID: 33931647
[TBL] [Abstract][Full Text] [Related]
2. CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
McNerney ME; Brown CD; Wang X; Bartom ET; Karmakar S; Bandlamudi C; Yu S; Ko J; Sandall BP; Stricker T; Anastasi J; Grossman RL; Cunningham JM; Le Beau MM; White KP
Blood; 2013 Feb; 121(6):975-83. PubMed ID: 23212519
[TBL] [Abstract][Full Text] [Related]
3. CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.
Ramdzan ZM; Nepveu A
Nat Rev Cancer; 2014 Oct; 14(10):673-82. PubMed ID: 25190083
[TBL] [Abstract][Full Text] [Related]
4. Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia.
McLornan D; Hay J; McLaughlin K; Holohan C; Burnett AK; Hills RK; Johnston PG; Mills KI; McMullin MF; Longley DB; Gilkes A
Br J Haematol; 2013 Jan; 160(2):188-98. PubMed ID: 23167276
[TBL] [Abstract][Full Text] [Related]
5. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.
Nabinger SC; Li XJ; Ramdas B; He Y; Zhang X; Zeng L; Richine B; Bowling JD; Fukuda S; Goenka S; Liu Z; Feng GS; Yu M; Sandusky GE; Boswell HS; Zhang ZY; Kapur R; Chan RJ
Leukemia; 2013 Feb; 27(2):398-408. PubMed ID: 23103841
[TBL] [Abstract][Full Text] [Related]
6. CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).
Burton LJ; Hawsawi O; Sweeney J; Bowen N; Hudson T; Odero-Marah V
PLoS One; 2019; 14(4):e0214844. PubMed ID: 30964885
[TBL] [Abstract][Full Text] [Related]
7. Inactivating CUX1 mutations promote tumorigenesis.
Wong CC; Martincorena I; Rust AG; Rashid M; Alifrangis C; Alexandrov LB; Tiffen JC; Kober C; ; Green AR; Massie CE; Nangalia J; Lempidaki S; Döhner H; Döhner K; Bray SJ; McDermott U; Papaemmanuil E; Campbell PJ; Adams DJ
Nat Genet; 2014 Jan; 46(1):33-8. PubMed ID: 24316979
[TBL] [Abstract][Full Text] [Related]
8. FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia.
Long J; Jia MY; Fang WY; Chen XJ; Mu LL; Wang ZY; Shen Y; Xiang RF; Wang LN; Wang L; Jiang CH; Jiang JL; Zhang WJ; Sun YD; Chang L; Gao WH; Wang Y; Li JM; Hong DL; Liang AB; Hu J
Blood; 2020 Apr; 135(17):1472-1483. PubMed ID: 32315388
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice.
Siam R; Harada R; Cadieux C; Battat R; Vadnais C; Nepveu A
Mol Cancer; 2009 Aug; 8():60. PubMed ID: 19656388
[TBL] [Abstract][Full Text] [Related]
10. p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin.
Kedinger V; Sansregret L; Harada R; Vadnais C; Cadieux C; Fathers K; Park M; Nepveu A
J Biol Chem; 2009 Oct; 284(40):27701-11. PubMed ID: 19635798
[TBL] [Abstract][Full Text] [Related]
11. The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Arthur RK; An N; Khan S; McNerney ME
Nucleic Acids Res; 2017 Jun; 45(11):6350-6361. PubMed ID: 28369554
[TBL] [Abstract][Full Text] [Related]
12. PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD
He X; Zhu Y; Lin YC; Li M; Du J; Dong H; Sun J; Zhu L; Wang H; Ding Z; Zhang L; Zhang L; Zhao D; Wang Z; Wu H; Zhang H; Jiang W; Xu Y; Jin J; Shen Y; Perry J; Zhao X; Zhang B; Liu S; Xue SL; Shen B; Chen CW; Chen J; Khaled S; Kuo YH; Marcucci G; Luo Y; Li L
Blood; 2019 Aug; 134(6):548-560. PubMed ID: 31217189
[TBL] [Abstract][Full Text] [Related]
13. Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.
Porath B; Livingston S; Andres EL; Petrie AM; Wright JC; Woo AE; Carlton CG; Baybutt R; Vanden Heuvel GB
Am J Physiol Renal Physiol; 2017 Oct; 313(4):F1050-F1059. PubMed ID: 28701314
[TBL] [Abstract][Full Text] [Related]
14. MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia.
Palma CA; Al Sheikha D; Lim TK; Bryant A; Vu TT; Jayaswal V; Ma DD
Mol Cancer; 2014 Apr; 13():79. PubMed ID: 24708856
[TBL] [Abstract][Full Text] [Related]
15. Targeting the Nuclear Cathepsin L CCAAT Displacement Protein/Cut Homeobox Transcription Factor-Epithelial Mesenchymal Transition Pathway in Prostate and Breast Cancer Cells with the Z-FY-CHO Inhibitor.
Burton LJ; Dougan J; Jones J; Smith BN; Randle D; Henderson V; Odero-Marah VA
Mol Cell Biol; 2017 Mar; 37(5):. PubMed ID: 27956696
[TBL] [Abstract][Full Text] [Related]
16. Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells.
Fiskus W; Sharma S; Qi J; Valenta JA; Schaub LJ; Shah B; Peth K; Portier BP; Rodriguez M; Devaraj SG; Zhan M; Sheng J; Iyer SP; Bradner JE; Bhalla KN
Mol Cancer Ther; 2014 May; 13(5):1142-54. PubMed ID: 24435446
[TBL] [Abstract][Full Text] [Related]
17. Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling.
Xu Y; Wang P; Li M; Wu Z; Li X; Shen J; Xu R
Biomed Pharmacother; 2021 Jan; 133():111054. PubMed ID: 33254022
[TBL] [Abstract][Full Text] [Related]
18. Hes1 suppresses acute myeloid leukemia development through FLT3 repression.
Kato T; Sakata-Yanagimoto M; Nishikii H; Ueno M; Miyake Y; Yokoyama Y; Asabe Y; Kamada Y; Muto H; Obara N; Suzukawa K; Hasegawa Y; Kitabayashi I; Uchida K; Hirao A; Yagita H; Kageyama R; Chiba S
Leukemia; 2015 Mar; 29(3):576-85. PubMed ID: 25234168
[TBL] [Abstract][Full Text] [Related]
19. Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation.
Hartman AD; Wilson-Weekes A; Suvannasankha A; Burgess GS; Phillips CA; Hincher KJ; Cripe LD; Boswell HS
Exp Hematol; 2006 Oct; 34(10):1360-76. PubMed ID: 16982329
[TBL] [Abstract][Full Text] [Related]
20. Molecular synergy underlies the co-occurrence patterns and phenotype of
Dovey OM; Cooper JL; Mupo A; Grove CS; Lynn C; Conte N; Andrews RM; Pacharne S; Tzelepis K; Vijayabaskar MS; Green P; Rad R; Arends M; Wright P; Yusa K; Bradley A; Varela I; Vassiliou GS
Blood; 2017 Oct; 130(17):1911-1922. PubMed ID: 28835438
[No Abstract] [Full Text] [Related]
[Next] [New Search]
