BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 36103824)

  • 1. BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer.
    Yan G; Luna A; Wang H; Bozorgui B; Li X; Sanchez M; Dereli Z; Kahraman N; Kara G; Chen X; Zheng C; McGrail D; Sahni N; Lu Y; Babur O; Cokol M; Lim B; Ozpolat B; Sander C; Mills GB; Korkut A
    Cell Rep; 2022 Sep; 40(11):111304. PubMed ID: 36103824
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Co-targeting bromodomain and extra-terminal proteins and MCL1 induces synergistic cell death in melanoma.
    Tseng HY; Dreyer J; Emran AA; Gunatilake D; Pirozyan M; Cullinane C; Dutton-Regester K; Rizos H; Hayward NK; McArthur G; Hersey P; Tiffen J; Gallagher S
    Int J Cancer; 2020 Oct; 147(8):2176-2189. PubMed ID: 32249419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of EGFR pathway promotes the cytotoxicity of ABT-263 in human leukemia K562 cells by blocking MCL1 upregulation.
    Lee YC; Wang LJ; Huang CH; Chiou JT; Shi YJ; Chang LS
    Biochem Pharmacol; 2020 Aug; 178():114047. PubMed ID: 32446890
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Breast cancer sub-types display heterogeneity in gene amplification and mRNA expression of the anti-apoptotic members of BCL2 family.
    Voutsadakis IA
    Gene; 2023 Mar; 857():147179. PubMed ID: 36627096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer.
    Gasca J; Flores ML; Giráldez S; Ruiz-Borrego M; Tortolero M; Romero F; Japón MA; Sáez C
    Oncotarget; 2016 Aug; 7(33):52751-52765. PubMed ID: 27409838
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone Deacetylase Inhibitor Enhances the Efficacy of MEK Inhibitor through NOXA-Mediated MCL1 Degradation in Triple-Negative and Inflammatory Breast Cancer.
    Torres-Adorno AM; Lee J; Kogawa T; Ordentlich P; Tripathy D; Lim B; Ueno NT
    Clin Cancer Res; 2017 Aug; 23(16):4780-4792. PubMed ID: 28465444
    [No Abstract]   [Full Text] [Related]  

  • 7. Molecular alterations in anti-apoptotic BCL2 family proteins in breast cancer cell line models, drug sensitivities and dependencies to guide the development of BCL2 inhibitors.
    Voutsadakis IA
    Gene; 2022 Dec; 847():146881. PubMed ID: 36100115
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tyrosine Kinase Inhibitors Increase MCL1 Degradation and in Combination with BCLXL/BCL2 Inhibitors Drive Prostate Cancer Apoptosis.
    Arai S; Jonas O; Whitman MA; Corey E; Balk SP; Chen S
    Clin Cancer Res; 2018 Nov; 24(21):5458-5470. PubMed ID: 30021909
    [No Abstract]   [Full Text] [Related]  

  • 9. ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression.
    Qi L; Zhang B; Zhang S; Ci X; Wu Q; Ma G; Luo A; Fu L; King JL; Nahta R; Dong JT
    Oncotarget; 2017 May; 8(22):36054-36066. PubMed ID: 28415602
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer.
    Farrugia MK; Sharma SB; Lin CC; McLaughlin SL; Vanderbilt DB; Ammer AG; Salkeni MA; Stoilov P; Agazie YM; Creighton CJ; Ruppert JM
    Cell Death Dis; 2015 Mar; 6(3):e1699. PubMed ID: 25789974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of MCL1 function sensitizes the MDA-MB-231 breast cancer cells to rh-TRAIL by increasing DR4 levels.
    De Blasio A; Pratelli G; Drago-Ferrante R; Saliba C; Baldacchino S; Grech G; Tesoriere G; Scerri C; Vento R; Di Fiore R
    J Cell Physiol; 2019 Aug; 234(10):18432-18447. PubMed ID: 30912136
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression.
    Chiou JT; Chang LS
    Apoptosis; 2024 Apr; 29(3-4):503-520. PubMed ID: 38066391
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transient targeting of BIM-dependent adaptive MCL1 preservation enhances tumor response to molecular therapeutics in non-small cell lung cancer.
    Shi K; Lu H; Zhang Z; Fu Y; Wu J; Zhou S; Ma P; Ye K; Zhang S; Shi H; Shi W; Cai MC; Zhao X; Yu Z; Tang J; Zhuang G
    Cell Death Differ; 2023 Jan; 30(1):195-207. PubMed ID: 36171331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy.
    Santer FR; Erb HH; Oh SJ; Handle F; Feiersinger GE; Luef B; Bu H; Schäfer G; Ploner C; Egger M; Rane JK; Maitland NJ; Klocker H; Eder IE; Culig Z
    Oncotarget; 2015 Mar; 6(8):6105-22. PubMed ID: 25749045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ELP-dependent expression of
    Cruz-Gordillo P; Honeywell ME; Harper NW; Leete T; Lee MJ
    Sci Signal; 2020 Nov; 13(658):. PubMed ID: 33203722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. β2-adrenoreceptor Signaling Increases Therapy Resistance in Prostate Cancer by Upregulating MCL1.
    Hassan S; Pullikuth A; Nelson KC; Flores A; Karpova Y; Baiz D; Zhu S; Sui G; Huang Y; Choi YA; D'Agostino R; Hemal A; von Holzen U; Debinski W; Kulik G
    Mol Cancer Res; 2020 Dec; 18(12):1839-1848. PubMed ID: 32928910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation.
    Arai S; Varkaris A; Nouri M; Chen S; Xie L; Balk SP
    Elife; 2020 Jun; 9():. PubMed ID: 32484436
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.
    Xia W; Petricoin EF; Zhao S; Liu L; Osada T; Cheng Q; Wulfkuhle JD; Gwin WR; Yang X; Gallagher RI; Bacus S; Lyerly HK; Spector NL
    Breast Cancer Res; 2013; 15(5):R85. PubMed ID: 24044505
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EGR3 and estrone are involved in the tamoxifen resistance and progression of breast cancer.
    Xie Y; Han X; Yu J; Yuan M; Yan Y; Qin J; Lan L; Wang Y
    J Cancer Res Clin Oncol; 2023 Dec; 149(20):18103-18117. PubMed ID: 37999751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells.
    Pratelli G; Carlisi D; Di Liberto D; Notaro A; Giuliano M; D'Anneo A; Lauricella M; Emanuele S; Calvaruso G; De Blasio A
    Int J Mol Sci; 2023 Jul; 24(13):. PubMed ID: 37446326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.