119 related articles for article (PubMed ID: 37937471)
1. Potent Anticancer Activity of a Dinuclear Gold(I) bis-N-Heterocyclic Imine Complex Related to Thioredoxin Reductase Inhibition in Vitro.
Park M; Schmidt C; Türck S; Hanusch F; Hirmer SV; Ott I; Casini A; Inoue S
Chempluschem; 2024 Apr; 89(4):e202300557. PubMed ID: 37937471
[TBL] [Abstract][Full Text] [Related]
2. Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram-Positive Directed Antibacterial Effects.
Schmidt C; Karge B; Misgeld R; Prokop A; Franke R; Brönstrup M; Ott I
Chemistry; 2017 Feb; 23(8):1869-1880. PubMed ID: 27865002
[TBL] [Abstract][Full Text] [Related]
3. Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.
Gandin V; Fernandes AP; Rigobello MP; Dani B; Sorrentino F; Tisato F; Björnstedt M; Bindoli A; Sturaro A; Rella R; Marzano C
Biochem Pharmacol; 2010 Jan; 79(2):90-101. PubMed ID: 19665452
[TBL] [Abstract][Full Text] [Related]
4. Anticancer profile of a series of gold(III) (2-phenyl)pyridine complexes.
Rubbiani R; Zehnder TN; Mari C; Blacque O; Venkatesan K; Gasser G
ChemMedChem; 2014 Dec; 9(12):2781-90. PubMed ID: 25377650
[TBL] [Abstract][Full Text] [Related]
5. Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches.
Karaca Ö; Scalcon V; Meier-Menches SM; Bonsignore R; Brouwer JMJL; Tonolo F; Folda A; Rigobello MP; Kühn FE; Casini A
Inorg Chem; 2017 Nov; 56(22):14237-14250. PubMed ID: 29095609
[TBL] [Abstract][Full Text] [Related]
6. Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells.
Zheng X; Xu W; Sun R; Yin H; Dong C; Zeng H
Chem Biol Interact; 2017 Sep; 275():74-85. PubMed ID: 28757135
[TBL] [Abstract][Full Text] [Related]
7. A binuclear gold(I) complex with mixed bridging diphosphine and bis(N-heterocyclic carbene) ligands shows favorable thiol reactivity and inhibits tumor growth and angiogenesis in vivo.
Zou T; Lum CT; Lok CN; To WP; Low KH; Che CM
Angew Chem Int Ed Engl; 2014 Jun; 53(23):5810-4. PubMed ID: 24729298
[TBL] [Abstract][Full Text] [Related]
8. Spectroscopic and electrochemical characterization of gold(I) and gold(III) complexes with glyoxaldehyde bis(thiosemicarbazones): cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
Lessa JA; Ferraz KS; Guerra JC; de Miranda LF; Romeiro CF; Souza-Fagundes EM; Barbeira PJ; Beraldo H
Biometals; 2012 Jun; 25(3):587-98. PubMed ID: 22526562
[TBL] [Abstract][Full Text] [Related]
9. Gold(I) thiotetrazolates as thioredoxin reductase inhibitors and antiproliferative agents.
Serebryanskaya TV; Lyakhov AS; Ivashkevich LS; Schur J; Frias C; Prokop A; Ott I
Dalton Trans; 2015 Jan; 44(3):1161-9. PubMed ID: 25413270
[TBL] [Abstract][Full Text] [Related]
10. Cationic and Neutral N-Heterocyclic Carbene Gold(I) Complexes: Cytotoxicity, NCI-60 Screening, Cellular Uptake, Inhibition of Mammalian Thioredoxin Reductase, and Reactive Oxygen Species Formation.
Zhang C; Hemmert C; Gornitzka H; Cuvillier O; Zhang M; Sun RW
ChemMedChem; 2018 Jun; 13(12):1218-1229. PubMed ID: 29603648
[TBL] [Abstract][Full Text] [Related]
11. Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands.
Vergara E; Casini A; Sorrentino F; Zava O; Cerrada E; Rigobello MP; Bindoli A; Laguna M; Dyson PJ
ChemMedChem; 2010 Jan; 5(1):96-102. PubMed ID: 19937669
[TBL] [Abstract][Full Text] [Related]
12. Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents.
Schuh E; Pflüger C; Citta A; Folda A; Rigobello MP; Bindoli A; Casini A; Mohr F
J Med Chem; 2012 Jun; 55(11):5518-28. PubMed ID: 22621714
[TBL] [Abstract][Full Text] [Related]
13. A gold(i) biscarbene complex with improved activity as a TrxR inhibitor and cytotoxic drug: comparative studies with different gold metallodrugs.
Schmidt C; Albrecht L; Balasupramaniam S; Misgeld R; Karge B; Brönstrup M; Prokop A; Baumann K; Reichl S; Ott I
Metallomics; 2019 Mar; 11(3):533-545. PubMed ID: 30516775
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of Action of Antitumor Au(I) N-Heterocyclic Carbene Complexes: A Computational Insight on the Targeting of TrxR Selenocysteine.
Tolbatov I; Umari P; Marrone A
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473872
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of both thioredoxin reductase and glutathione reductase may contribute to the anticancer mechanism of TH-302.
Li S; Zhang J; Li J; Chen D; Matteucci M; Curd J; Duan JX
Biol Trace Elem Res; 2010 Sep; 136(3):294-301. PubMed ID: 19838642
[TBL] [Abstract][Full Text] [Related]
16. Novel antitumor adamantane-azole gold(I) complexes as potential inhibitors of thioredoxin reductase.
Garcia A; Machado RC; Grazul RM; Lopes MT; Corrêa CC; Dos Santos HF; de Almeida MV; Silva H
J Biol Inorg Chem; 2016 Apr; 21(2):275-92. PubMed ID: 26841791
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition.
Guarra F; Busto N; Guerri A; Marchetti L; Marzo T; García B; Biver T; Gabbiani C
J Inorg Biochem; 2020 Apr; 205():110998. PubMed ID: 31981769
[TBL] [Abstract][Full Text] [Related]
18. Gold(I) N-heterocyclic carbene complexes with naphthalimide ligands as combined thioredoxin reductase inhibitors and DNA intercalators.
Meyer A; Oehninger L; Geldmacher Y; Alborzinia H; Wölfl S; Sheldrick WS; Ott I
ChemMedChem; 2014 Aug; 9(8):1794-800. PubMed ID: 24803348
[TBL] [Abstract][Full Text] [Related]
19. Gold(I) complex of N,N'-disubstituted cyclic thiourea with in vitro and in vivo anticancer properties-potent tight-binding inhibition of thioredoxin reductase.
Yan K; Lok CN; Bierla K; Che CM
Chem Commun (Camb); 2010 Nov; 46(41):7691-3. PubMed ID: 20623063
[TBL] [Abstract][Full Text] [Related]
20. Antiglioma activity of GoPI-sugar, a novel gold(I)-phosphole inhibitor: chemical synthesis, mechanistic studies, and effectiveness in vivo.
Jortzik E; Farhadi M; Ahmadi R; Tóth K; Lohr J; Helmke BM; Kehr S; Unterberg A; Ott I; Gust R; Deborde V; Davioud-Charvet E; Réau R; Becker K; Herold-Mende C
Biochim Biophys Acta; 2014 Aug; 1844(8):1415-26. PubMed ID: 24440405
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]