BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 38453907)

  • 1. Regulation of HOX gene expression in AML.
    Khan I; Amin MA; Eklund EA; Gartel AL
    Blood Cancer J; 2024 Mar; 14(1):42. PubMed ID: 38453907
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.
    Kühn MW; Song E; Feng Z; Sinha A; Chen CW; Deshpande AJ; Cusan M; Farnoud N; Mupo A; Grove C; Koche R; Bradner JE; de Stanchina E; Vassiliou GS; Hoshii T; Armstrong SA
    Cancer Discov; 2016 Oct; 6(10):1166-1181. PubMed ID: 27535106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias.
    Mullighan CG; Kennedy A; Zhou X; Radtke I; Phillips LA; Shurtleff SA; Downing JR
    Leukemia; 2007 Sep; 21(9):2000-9. PubMed ID: 17597811
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Garzon R; Garofalo M; Martelli MP; Briesewitz R; Wang L; Fernandez-Cymering C; Volinia S; Liu CG; Schnittger S; Haferlach T; Liso A; Diverio D; Mancini M; Meloni G; Foa R; Martelli MF; Mecucci C; Croce CM; Falini B
    Proc Natl Acad Sci U S A; 2008 Mar; 105(10):3945-50. PubMed ID: 18308931
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular synergy underlies the co-occurrence patterns and phenotype of
    Dovey OM; Cooper JL; Mupo A; Grove CS; Lynn C; Conte N; Andrews RM; Pacharne S; Tzelepis K; Vijayabaskar MS; Green P; Rad R; Arends M; Wright P; Yusa K; Bradley A; Varela I; Vassiliou GS
    Blood; 2017 Oct; 130(17):1911-1922. PubMed ID: 28835438
    [No Abstract]   [Full Text] [Related]  

  • 6. HOX expression patterns identify a common signature for favorable AML.
    Andreeff M; Ruvolo V; Gadgil S; Zeng C; Coombes K; Chen W; Kornblau S; Barón AE; Drabkin HA
    Leukemia; 2008 Nov; 22(11):2041-7. PubMed ID: 18668134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NPM1-mutated acute myeloid leukemia: New pathogenetic and therapeutic insights and open questions.
    Falini B
    Am J Hematol; 2023 Sep; 98(9):1452-1464. PubMed ID: 37317978
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant NPM1 Maintains the Leukemic State through HOX Expression.
    Brunetti L; Gundry MC; Sorcini D; Guzman AG; Huang YH; Ramabadran R; Gionfriddo I; Mezzasoma F; Milano F; Nabet B; Buckley DL; Kornblau SM; Lin CY; Sportoletti P; Martelli MP; Falini B; Goodell MA
    Cancer Cell; 2018 Sep; 34(3):499-512.e9. PubMed ID: 30205049
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells.
    Kawagoe H; Humphries RK; Blair A; Sutherland HJ; Hogge DE
    Leukemia; 1999 May; 13(5):687-98. PubMed ID: 10374871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic targeting in pediatric acute myeloid leukemia with aberrant HOX/MEIS1 expression.
    Juul-Dam KL; Shukla NN; Cooper TM; Cuglievan B; Heidenreich O; Kolb EA; Rasouli M; Hasle H; Zwaan CM
    Eur J Med Genet; 2023 Dec; 66(12):104869. PubMed ID: 38174649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the undruggable: menin inhibitors ante portas.
    Dempke WCM; Desole M; Chiusolo P; Sica S; Schmidt-Hieber M
    J Cancer Res Clin Oncol; 2023 Sep; 149(11):9451-9459. PubMed ID: 37103568
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells.
    Ghasemi R; Struthers H; Wilson ER; Spencer DH
    Leukemia; 2021 Feb; 35(2):404-416. PubMed ID: 32398790
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.
    Zhu G; Luo H; Feng Y; Guryanova OA; Xu J; Chen S; Lai Q; Sharma A; Xu B; Zhao Z; Feng R; Ni H; Claxton D; Guo Y; Mesa RA; Qiu Y; Yang FC; Li W; Nimer SD; Huang S; Xu M
    Nat Commun; 2021 Mar; 12(1):1956. PubMed ID: 33782403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NPM1-mutated acute myeloid leukemia: from bench to bedside.
    Falini B; Brunetti L; Sportoletti P; Martelli MP
    Blood; 2020 Oct; 136(15):1707-1721. PubMed ID: 32609823
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1-mutated AML.
    Pianigiani G; Gagliardi A; Mezzasoma F; Rocchio F; Tini V; Bigerna B; Sportoletti P; Caruso S; Marra A; Peruzzi S; Petito E; Spinozzi G; Shacham S; Landesman Y; Quintarelli C; Gresele P; Locatelli F; Martelli MP; Falini B; Brunetti L
    Blood Adv; 2022 Nov; 6(22):5938-5949. PubMed ID: 36037515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.
    Haferlach C; Mecucci C; Schnittger S; Kohlmann A; Mancini M; Cuneo A; Testoni N; Rege-Cambrin G; Santucci A; Vignetti M; Fazi P; Martelli MP; Haferlach T; Falini B
    Blood; 2009 Oct; 114(14):3024-32. PubMed ID: 19429869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Current status and future perspectives in targeted therapy of NPM1-mutated AML.
    Ranieri R; Pianigiani G; Sciabolacci S; Perriello VM; Marra A; Cardinali V; Pierangeli S; Milano F; Gionfriddo I; Brunetti L; Martelli MP; Falini B
    Leukemia; 2022 Oct; 36(10):2351-2367. PubMed ID: 36008542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes.
    Darracq A; Pak H; Bourgoin V; Zmiri F; Dellaire G; Affar EB; Milot E
    PLoS Genet; 2019 Nov; 15(11):e1008463. PubMed ID: 31675375
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
    Dawson MA; Gudgin EJ; Horton SJ; Giotopoulos G; Meduri E; Robson S; Cannizzaro E; Osaki H; Wiese M; Putwain S; Fong CY; Grove C; Craig J; Dittmann A; Lugo D; Jeffrey P; Drewes G; Lee K; Bullinger L; Prinjha RK; Kouzarides T; Vassiliou GS; Huntly BJ
    Leukemia; 2014 Feb; 28(2):311-20. PubMed ID: 24220271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CTCF boundary remodels chromatin domain and drives aberrant
    Luo H; Wang F; Zha J; Li H; Yan B; Du Q; Yang F; Sobh A; Vulpe C; Drusbosky L; Cogle C; Chepelev I; Xu B; Nimer SD; Licht J; Qiu Y; Chen B; Xu M; Huang S
    Blood; 2018 Aug; 132(8):837-848. PubMed ID: 29760161
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.