BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 38542901)

  • 1. Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior.
    Hindle SJ; Munji RN; Dolghih E; Gaskins G; Orng S; Ishimoto H; Soung A; DeSalvo M; Kitamoto T; Keiser MJ; Jacobson MP; Daneman R; Bainton RJ
    Cell Rep; 2017 Oct; 21(5):1304-1316. PubMed ID: 29091768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Explaining Blood-Brain Barrier Permeability of Small Molecules by Integrated Analysis of Different Transport Mechanisms.
    Cornelissen FMG; Markert G; Deutsch G; Antonara M; Faaij N; Bartelink I; Noske D; Vandertop WP; Bender A; Westerman BA
    J Med Chem; 2023 Jun; 66(11):7253-7267. PubMed ID: 37217193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Machine Learning Exploration of the Relationship Between Drugs and the Blood-Brain Barrier: Guiding Molecular Modification.
    Yang Q; Fan L; Hao E; Hou X; Deng J; Xia Z; Du Z
    Pharm Res; 2024 May; 41(5):863-875. PubMed ID: 38605261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Empirical Analysis of Drug Targets for Nervous System Disorders.
    Mueller LG; Slusher BS; Tsukamoto T
    ACS Chem Neurosci; 2024 Feb; 15(3):394-399. PubMed ID: 38237559
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identifying Substructures That Facilitate Compounds to Penetrate the Blood-Brain Barrier via Passive Transport Using Machine Learning Explainer Models.
    Rosa LCS; Argolo CO; Nascimento CMC; Pimentel AS
    ACS Chem Neurosci; 2024 Jun; 15(11):2144-2159. PubMed ID: 38723285
    [TBL] [Abstract][Full Text] [Related]  

  • 6.
    Rathi S; Oh JH; Zhang W; Mladek AC; Garcia DA; Xue Z; Burgenske DM; Zhang W; Le J; Zhong W; Sarkaria JN; Elmquist WF
    J Pharmacol Exp Ther; 2024 Jun; ():. PubMed ID: 38858089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery.
    Huang L; Wells MC; Zhao Z
    Drug Metab Lett; 2019; 13(2):78-94. PubMed ID: 30854983
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Experimental and Computational Methods to Assess Central Nervous System Penetration of Small Molecules.
    Gupta M; Feng J; Bhisetti G
    Molecules; 2024 Mar; 29(6):. PubMed ID: 38542901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening.
    Ye D; Harder A; Fang Z; Weinheimer M; Laplanche L; Mezler M
    Pharm Res; 2020 Sep; 37(10):194. PubMed ID: 32918191
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Harnessing Preclinical Data as a Predictive Tool for Human Brain Tissue Targeting.
    Patel NC; Feng B; Hou X; West MA; Trapa PE; Sciabola S; Verhoest P; Liras JL; Maurer TS; Wager TT
    ACS Chem Neurosci; 2021 Mar; 12(6):1007-1017. PubMed ID: 33651587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier.
    Colclough N; Alluri RV; Tucker JW; Gozalpour E; Li D; Du H; Li W; Harlfinger S; O'Neill DJ; Sproat GG; Chen K; Yan Y; McGinnity DF
    Drug Metab Dispos; 2024 Jan; 52(2):95-105. PubMed ID: 38071533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of Human Brain Penetration of P-glycoprotein and Breast Cancer Resistance Protein Substrates Using In Vitro Transporter Studies and Animal Models.
    Feng B; Doran AC; Di L; West MA; Osgood SM; Mancuso JY; Shaffer CL; Tremaine L; Liras J
    J Pharm Sci; 2018 Aug; 107(8):2225-2235. PubMed ID: 29608887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in the in vitro and in vivo methods to assess impact of P-glycoprotein and breast cancer resistance protein transporters in central nervous system drug disposition.
    Chatterjee S; Deshpande AA; Shen H
    Biopharm Drug Dispos; 2023 Feb; 44(1):7-25. PubMed ID: 36692150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Accurate prediction of K
    Ma Y; Jiang M; Javeria H; Tian D; Du Z
    Heliyon; 2024 Jan; 10(2):e24304. PubMed ID: 38298681
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 8.