BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 38653790)

  • 1. Exploring a repurposed candidate with dual hIDO1/hTDO2 inhibitory potential for anticancer efficacy identified through pharmacophore-based virtual screening and in vitro evaluation.
    Aboomar NM; Essam O; Hassan A; Bassiouny AR; Arafa RK
    Sci Rep; 2024 Apr; 14(1):9386. PubMed ID: 38653790
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase.
    Pham KN; Lewis-Ballester A; Yeh SR
    J Am Chem Soc; 2019 Nov; 141(47):18771-18779. PubMed ID: 31682426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as IDO1/TDO dual inhibitors.
    Cui G; Lai F; Wang X; Chen X; Xu B
    Eur J Med Chem; 2020 Feb; 188():111985. PubMed ID: 31881488
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening.
    Sari S; Tomek P; Leung E; Reynisson J
    Molecules; 2019 Nov; 24(23):. PubMed ID: 31795096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational study on new natural compound inhibitors of indoleamine 2,3-dioxygenase 1.
    Jiang S; Li H; Piao L; Jin Z; Liu J; Chen S; Liu LL; Shao Y; Zhong S; Wu B; Li W; Ren J; Zhang Y; Wang H; Jin R
    Aging (Albany NY); 2020 Jun; 12(12):11349-11363. PubMed ID: 32568737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Basis of Selective Human Indoleamine-2,3-dioxygenase 1 (hIDO1) Inhibition.
    Kassab SE; Mowafy S
    ChemMedChem; 2021 Oct; 16(20):3149-3164. PubMed ID: 34174026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).
    Pan S; Zhou Y; Wang Q; Wang Y; Tian C; Wang T; Huang L; Nan J; Li L; Yang S
    Eur J Med Chem; 2020 Dec; 207():112703. PubMed ID: 32871341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors.
    Yang L; Chen Y; He J; Njoya EM; Chen J; Liu S; Xie C; Huang W; Wang F; Wang Z; Li Y; Qian S
    Bioorg Med Chem; 2019 Mar; 27(6):1087-1098. PubMed ID: 30773421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.
    Ning XL; Li YZ; Huo C; Deng J; Gao C; Zhu KR; Wang M; Wu YX; Yu JL; Ren YL; Luo ZY; Li G; Chen Y; Wang SY; Peng C; Yang LL; Wang ZY; Wu Y; Qian S; Li GB
    J Med Chem; 2021 Jun; 64(12):8303-8332. PubMed ID: 34110158
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth.
    Panda S; Pradhan N; Chatterjee S; Morla S; Saha A; Roy A; Kumar S; Bhattacharyya A; Manna D
    Sci Rep; 2019 Dec; 9(1):18455. PubMed ID: 31804586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of novel tryptanthrin derivatives as dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase.
    Li Y; Zhang S; Wang R; Cui M; Liu W; Yang Q; Kuang C
    Bioorg Med Chem Lett; 2020 Jun; 30(11):127159. PubMed ID: 32247733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A highly efficient modality to block the degradation of tryptophan for cancer immunotherapy: locked nucleic acid-modified antisense oligonucleotides to inhibit human indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase expression.
    Klar R; Michel S; Schell M; Hinterwimmer L; Zippelius A; Jaschinski F
    Cancer Immunol Immunother; 2020 Jan; 69(1):57-67. PubMed ID: 31802183
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    Yang D; Zhang S; Fang X; Guo L; Hu N; Guo Z; Li X; Yang S; He JC; Kuang C; Yang Q
    J Med Chem; 2019 Oct; 62(20):9161-9174. PubMed ID: 31580660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microtubule inhibitors containing immunostimulatory agents promote cancer immunochemotherapy by inhibiting tubulin polymerization and tryptophan-2,3-dioxygenase.
    Hua S; Chen F; Gou S
    Eur J Med Chem; 2020 Feb; 187():111949. PubMed ID: 31830637
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors.
    Song X; Sun P; Wang J; Guo W; Wang Y; Meng LH; Liu H
    Eur J Med Chem; 2020 Mar; 189():112059. PubMed ID: 31981851
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of paeoniflorin from Paeonia lactiflora pall. As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice.
    Liang X; Su T; Wu P; Dai Y; Chen Y; Wang Q; Cao C; Chen F; Wang Q; Wang S
    J Ethnopharmacol; 2023 Dec; 317():116714. PubMed ID: 37315645
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes.
    Seegers N; van Doornmalen AM; Uitdehaag JC; de Man J; Buijsman RC; Zaman GJ
    J Biomol Screen; 2014 Oct; 19(9):1266-74. PubMed ID: 24870017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO).
    Zhang S; Guo L; Yang D; Xing Z; Li W; Kuang C; Yang Q
    Bioorg Chem; 2020 Nov; 104():104348. PubMed ID: 33142415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors.
    Chen S; Guo W; Liu X; Sun P; Wang Y; Ding C; Meng L; Zhang A
    Eur J Med Chem; 2019 Oct; 179():38-55. PubMed ID: 31233921
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of IDO1 and DNA dual targeting antitumor agents.
    Fang K; Wu S; Dong G; Wu Y; Chen S; Liu J; Wang W; Sheng C
    Org Biomol Chem; 2017 Dec; 15(47):9992-9995. PubMed ID: 29177308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.