115 related articles for article (PubMed ID: 38686671)
1. Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
Zhao M; Ye N; Liu L; Zhang RJ; Li N; Peng J; Cai XY; Jiang XQ; Su KY; Zhang XL; Rao QR; Liu KJ; Deng DX; Peng AH; Tang MH; Chen LJ; Wu WS; Ye HY
J Med Chem; 2024 May; 67(9):7516-7538. PubMed ID: 38686671
[TBL] [Abstract][Full Text] [Related]
2. Discovery of dronedarone and its analogues as NLRP3 inflammasome inhibitors with potent anti-inflammation activity.
Chen H; Chen X; Sun P; Wu D; Yue H; Pan J; Li X; Zhang C; Wu X; Hua L; Hu W; Yang Z
Bioorg Med Chem Lett; 2021 Aug; 46():128160. PubMed ID: 34062252
[TBL] [Abstract][Full Text] [Related]
3. Discovery of Novel Pterostilbene-Based Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors with Inflammatory Activity for Colitis.
Chen LZ; Zhang XX; Liu MM; Wu J; Ma D; Diao LZ; Li Q; Huang YS; Zhang R; Ruan BF; Liu XH
J Med Chem; 2021 Sep; 64(18):13633-13657. PubMed ID: 34506712
[TBL] [Abstract][Full Text] [Related]
4. Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis.
Dai Z; Chen XY; An LY; Li CC; Zhao N; Yang F; You ST; Hou CZ; Li K; Jiang C; You QD; Di B; Xu LL
J Med Chem; 2021 Jan; 64(1):871-889. PubMed ID: 33332136
[TBL] [Abstract][Full Text] [Related]
5. Discovery of pterostilbene analogs as novel NLRP3 inflammasome inhibitors for potential treatment of DSS-induced colitis in mice.
Ruan B; Rong M; Ming Z; Wang K; Liu X; Deng L; Zhang X; Xu K; Shi C; Gao T; Liu X; Chen L
Bioorg Chem; 2023 Apr; 133():106429. PubMed ID: 36841048
[TBL] [Abstract][Full Text] [Related]
6. Discovery of Triazinone Derivatives as Novel, Specific, and Direct NLRP3 Inflammasome Inhibitors for the Treatment of DSS-Induced Ulcerative Colitis.
Li N; Jiang X; Zhang R; Ye N; Tang M; Cai X; Su K; Peng J; Zhang X; Zhao M; Wu W; Ye H
J Med Chem; 2023 Oct; 66(19):13428-13451. PubMed ID: 37756547
[TBL] [Abstract][Full Text] [Related]
7. Discovery of 4-((E)-3,5-dimethoxy-2-((E)-2-nitrovinyl)styryl)aniline derivatives as potent and orally active NLRP3 inflammasome inhibitors for colitis.
Zhang XX; Diao LZ; Chen LZ; Ma D; Wang YM; Jiang H; Ruan BF; Liu XH
Eur J Med Chem; 2022 Jun; 236():114357. PubMed ID: 35428012
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of parthenolide derivatives with reduced toxicity as potential inhibitors of the NLRP3 inflammasome.
Ou Y; Sun P; Wu N; Chen H; Wu D; Hu W; Yang Z
Bioorg Med Chem Lett; 2020 Sep; 30(17):127399. PubMed ID: 32738997
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and biological evaluation of tanshinone IIA derivatives as NLRP3 inflammasome inhibitors.
Chen H; Yue H; Yan Y; Wu N; Wu D; Sun P; Hu W; Yang Z
Bioorg Med Chem Lett; 2024 May; 104():129725. PubMed ID: 38555073
[TBL] [Abstract][Full Text] [Related]
10. Heat shock transcription factor 2 reduces the secretion of IL-1β by inhibiting NLRP3 inflammasome activation in ulcerative colitis.
Zhang F; Zhao W; Zhou J; Wang W; Luo J; Feng Y; Wu J; Li M; Wang K; Niu J; Miao Y
Gene; 2021 Feb; 768():145299. PubMed ID: 33181254
[TBL] [Abstract][Full Text] [Related]
11. 3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome.
Wang Y; Wang H; Qian C; Tang J; Zhou W; Liu X; You Q; Hu R
Biochem Pharmacol; 2016 Feb; 101():71-86. PubMed ID: 26588861
[TBL] [Abstract][Full Text] [Related]
12. Growth differentiation factor 11 ameliorates experimental colitis by inhibiting NLRP3 inflammasome activation.
Wang L; Wang Y; Wang Z; Qi Y; Zong B; Liu M; Li X; Zhang X; Liu C; Cao R; Ma Y
Am J Physiol Gastrointest Liver Physiol; 2018 Dec; 315(6):G909-G920. PubMed ID: 30188752
[TBL] [Abstract][Full Text] [Related]
13. The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.
Tang T; Li P; Zhou X; Wang R; Fan X; Yang M; Qi K
Front Immunol; 2021; 12():741839. PubMed ID: 34512673
[TBL] [Abstract][Full Text] [Related]
14. Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization.
Qin Q; Xu G; Zhan X; Wang Z; Wang Y; Liu H; Hou X; Shi W; Ma J; Bai Z; Xiao X
Mol Immunol; 2021 Jul; 135():116-126. PubMed ID: 33892379
[TBL] [Abstract][Full Text] [Related]
15. Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities.
Zhang C; Yue H; Sun P; Hua L; Liang S; Ou Y; Wu D; Wu X; Chen H; Hao Y; Hu W; Yang Z
Eur J Med Chem; 2021 Jul; 219():113417. PubMed ID: 33845232
[TBL] [Abstract][Full Text] [Related]
16. 1'-Acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression.
Sok SPM; Ori D; Wada A; Okude H; Kawasaki T; Momota M; Nagoor NH; Kawai T
Int Immunol; 2021 Jun; 33(7):373-386. PubMed ID: 33830232
[TBL] [Abstract][Full Text] [Related]
17. Ginsenoside Rd ameliorates colitis by inducing p62-driven mitophagy-mediated NLRP3 inflammasome inactivation in mice.
Liu C; Wang J; Yang Y; Liu X; Zhu Y; Zou J; Peng S; Le TH; Chen Y; Zhao S; He B; Mi Q; Zhang X; Du Q
Biochem Pharmacol; 2018 Sep; 155():366-379. PubMed ID: 30012462
[TBL] [Abstract][Full Text] [Related]
18. Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway.
Liu Q; Zuo R; Wang K; Nong FF; Fu YJ; Huang SW; Pan ZF; Zhang Y; Luo X; Deng XL; Zhang XX; Zhou L; Chen Y
Acta Pharmacol Sin; 2020 Jun; 41(6):771-781. PubMed ID: 31937929
[TBL] [Abstract][Full Text] [Related]
19. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.
Jiao Y; Nan J; Mu B; Zhang Y; Zhou N; Yang S; Zhang S; Lin W; Wang F; Xia A; Cao Z; Chen P; Pan Z; Lin G; Pan S; Bin H; Li L; Yang S
Eur J Med Chem; 2022 Mar; 232():114194. PubMed ID: 35183871
[TBL] [Abstract][Full Text] [Related]
20. Britannin as a novel NLRP3 inhibitor, suppresses inflammasome activation in macrophages and alleviates NLRP3-related diseases in mice.
Shao JJ; Li WF; Sun JF; Zhuang ZS; Min JL; Long XH; Wu GJ; Xu HW; Liang G
Acta Pharmacol Sin; 2024 Apr; 45(4):803-814. PubMed ID: 38172305
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
