BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND ATM, TELO1, 472, ENSG00000149311, TEL1, ATD, ATE, DKFZp781A0353, AT1, Q13315, MGC74674, ATDC, ATC, ATA
790 results:

  • 1. GZ17-6.02 kills PDX isolates of uveal melanoma.
    Booth L; Roberts JL; Spasojevic I; Baker KC; Poklepovic A; West C; Kirkwood JM; Dent P
    Oncotarget; 2024 May; 15():328-344. PubMed ID: 38758815
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
    Vanni I; Pastorino L; Andreotti V; Comandini D; Fornarini G; Grassi M; Puccini A; Tanda ET; Pastorino A; Martelli V; Mastracci L; Grillo F; Cabiddu F; Guadagno A; Coco S; Allavena E; Barbero F; Bruno W; Dalmasso B; Bellomo SE; Marchiò C; Spagnolo F; Sciallero S; Berrino E; Ghiorzo P
    J Transl Med; 2024 May; 22(1):462. PubMed ID: 38750555
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Characterizing the presentation, management, and clinical outcomes of patients with intradural spinal chordomas: a systematic review.
    Saint-Germain MA; Kramer P; Weber-Levine C; Jiang K; Al-Mistarehi AH; Redmond KJ; Lee SH; Bettegowda C; Theodore N; Lubelski D
    Neurosurg Focus; 2024 May; 56(5):E14. PubMed ID: 38691865
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The immune response-related genomic alterations in patients with malignant melanoma.
    Li L; Xiang T; Li X
    Medicine (Baltimore); 2024 Apr; 103(17):e37966. PubMed ID: 38669390
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2.
    Fan Y; Chen S; Chu C; Yin X; Jin J; Zhang L; Yan H; Cao Z; Liu R; Xin M; Li L; Yin C
    J Ovarian Res; 2024 Mar; 17(1):67. PubMed ID: 38528613
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genomic drivers in craniopharyngiomas: Analysis of the AACR project GENIE database.
    Lehrich MB; Tong CLC; Hsu PKF; Kuan CE
    Childs Nerv Syst; 2024 Jun; 40(6):1661-1669. PubMed ID: 38421446
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis.
    Chen W; Hao P; Song Q; Feng X; Zhao X; Wu J; Gong Z; Zhang J; Fu X; Wang X
    Metab Brain Dis; 2024 Apr; 39(4):625-633. PubMed ID: 38416338
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Aberrant atm signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization.
    Chen J; Laverty DJ; Talele S; Bale A; Carlson BL; Porath KA; Bakken KK; Burgenske DM; Decker PA; Vaubel RA; Eckel-Passow JE; Bhargava R; Lou Z; Hamerlik P; Harley B; Elmquist WF; Nagel ZD; Gupta SK; Sarkaria JN
    Sci Transl Med; 2024 Feb; 16(734):eadj5962. PubMed ID: 38354228
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The atm Ser49Cys Variant Effects atm Function as a Regulator of Oncogene-Induced Senescence.
    Atkinson C; McInerney-Leo AM; Proctor M; Lanagan C; Stevenson AJ; Dehkhoda F; Caole M; Maas E; Ainger S; Pritchard AL; Johansson PA; Leo P; Hayward NK; Sturm RA; Duncan EL; Gabrielli B
    Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338943
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Transformation of G1-G2 neuroendocrine tumors to neuroendocrine carcinomas following peptide receptor radionuclide therapy.
    Cordero-Hernandez IS; Ross AC; Dasari A; Halperin DM; Chasen B; Yao JC
    Endocr Relat Cancer; 2024 Apr; 31(4):. PubMed ID: 38329269
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Correlation of fitzpatrick skin type and iris color with tumor size in 823 patients with uveal melanoma.
    Agrawal KU; Barke MR; Chiang L; Ni R; Kim RS; Zhang Q; Shields CL
    Asia Pac J Ophthalmol (Phila); 2024; 13(2):100046. PubMed ID: 38320655
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of Novel, Selective ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.
    Pike KG; Hunt TA; Barlaam B; Benstead D; Cadogan E; Chen K; Cook CR; Colclough N; Deng C; Durant ST; Eatherton A; Goldberg K; Johnström P; Liu L; Liu Z; Nissink JWM; Pang C; Pass M; Robb GR; Roberts C; Schou M; Steward O; Sykes A; Yan Y; Zhai B; Zheng L
    J Med Chem; 2024 Feb; 67(4):3090-3111. PubMed ID: 38306388
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Simulated microgravity induces DNA damage concurrent with impairment of DNA repair and activation of cell-type specific DNA damage response in microglial and glioblastoma cells.
    Singh R; Jaiswal A; Singh RP
    Biochim Biophys Acta Mol Cell Res; 2024 Mar; 1871(3):119679. PubMed ID: 38272357
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms.
    Cowzer D; Shah RH; Chou JF; Kundra R; Punn S; Fiedler L; DeMore A; Capanu M; Berger MF; Reidy-Lagunes D; Raj N
    Endocr Relat Cancer; 2024 Apr; 31(4):. PubMed ID: 38252063
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Somatic Versus germline: A Case Series of Three Children With
    Tam LT; Cole B; Stasi SM; Paulson VA; Wright JN; Hoeppner C; Holtzclaw S; Crotty EE; Ellenbogen RG; Lee A; Ermoian RP; Lockwood CM; Leary SES; Ronsley R
    JCO Precis Oncol; 2024 Jan; 8():e2300333. PubMed ID: 38207225
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Genetic Risk Factors for Early-Onset Merkel cell Carcinoma.
    Mohsin N; Hunt D; Yan J; Jabbour AJ; Nghiem P; Choi J; Zhang Y; Freeman AF; Bergerson JRE; Dell'Orso S; Lachance K; Kulikauskas R; Collado L; Cao W; Lack J; Similuk M; Seifert BA; Ghosh R; Walkiewicz MA; Brownell I
    JAMA Dermatol; 2024 Feb; 160(2):172-178. PubMed ID: 38170500
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Presumed Pathogenic germ Line and Somatic Variants in African American Thyroid Cancer.
    Hurst ZA; Liyanarachchi S; Brock P; He H; Nabhan F; Veloski C; Toland AE; Ringel MD; Jhiang SM
    Thyroid; 2024 Mar; 34(3):378-387. PubMed ID: 38062767
    [No Abstract]    [Full Text] [Related]  

  • 18. Nivolumab Plus Ipilimumab in Patients With Solid tumors With
    Rohatgi N; Rothe M; Mangat PK; Garrett-Mayer E; Meric-Bernstam F; Pisick E; Alese OB; Reynolds CM; Thota R; Vaccaro GM; von Mehren M; Arend RC; Chiu VK; Duvivier HL; Gold PJ; Hack K; Marr AS; Winer A; Grantham GN; Hinshaw DC; Gregory A; Halabi S; Schilsky RL
    JCO Precis Oncol; 2023 Sep; 7():e2300279. PubMed ID: 38039429
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Invasion-Block and S-MARVEL: A high-content screening and image analysis platform identifies atm kinase as a modulator of melanoma invasion and metastasis.
    Guo D; Jurek R; Beaumont KA; Sharp DS; Tan SY; Mariana A; Failes TW; Grootveld AK; Bhattacharyya ND; Phan TG; Arndt GM; Jain R; Weninger W; Tikoo S
    Proc Natl Acad Sci U S A; 2023 Nov; 120(47):e2303978120. PubMed ID: 37963252
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Reasoning and causal inference regarding surgical options for patients with low-grade gliomas using machine learning: A SEER-based study.
    Zhu E; Shi W; Chen Z; Wang J; Ai P; Wang X; Zhu M; Xu Z; Xu L; Sun X; Liu J; Xu X; Shan D
    Cancer Med; 2023 Nov; 12(22):20878-20891. PubMed ID: 37929878
    [TBL] [Abstract] [Full Text] [Related]  


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