Terms: = Germ cell tumor AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Treatment
1407 results:
1. Cholesterol neutralized vemurafenib treatment by promoting melanoma stem-like cells via its metabolite 27-hydroxycholesterol.
Wang X; Zhong F; Chen T; Wang H; Wang W; Jin H; Li C; Guo X; Liu Y; Zhang Y; Li B
Cell Mol Life Sci; 2024 May; 81(1):226. PubMed ID: 38775844
[TBL] [Abstract] [Full Text] [Related]
2. CRISPR-Cas9 library screening combined with an exosome-targeted delivery system addresses tumorigenesis/TMZ resistance in the mesenchymal subtype of glioblastoma.
Zhao J; Cui X; Zhan Q; Zhang K; Su D; Yang S; Hong B; Wang Q; Ju J; Cheng C; Li C; Wan C; Wang Y; Zhou J; Kang C
Theranostics; 2024; 14(7):2835-2855. PubMed ID: 38773970
[No Abstract] [Full Text] [Related]
3. LINC00606 promotes glioblastoma progression through sponge miR-486-3p and interaction with ATP11B.
Dong N; Qi W; Wu L; Li J; Zhang X; Wu H; Zhang W; Jiang J; Zhang S; Fu W; Liu Q; Qi G; Wang L; Lu Y; Luo J; Kong Y; Liu Y; Zhao RC; Wang J
J Exp Clin Cancer Res; 2024 May; 43(1):139. PubMed ID: 38725030
[TBL] [Abstract] [Full Text] [Related]
4. Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress.
Lu Z; Sun GF; He KY; Zhang Z; Han XH; Qu XH; Wan DF; Yao D; Tou FF; Han XJ; Wang T
Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167220. PubMed ID: 38718847
[TBL] [Abstract] [Full Text] [Related]
5. A review on potential heterocycles for the treatment of glioblastoma targeting receptor tyrosine kinases.
Bhusare N; Kumar M
Oncol Res; 2024; 32(5):849-875. PubMed ID: 38686058
[TBL] [Abstract] [Full Text] [Related]
6. Principles in the Management of Glioblastoma.
Roda D; Veiga P; Melo JB; Carreira IM; Ribeiro IP
Genes (Basel); 2024 Apr; 15(4):. PubMed ID: 38674436
[TBL] [Abstract] [Full Text] [Related]
7. LncRNA NDUFA6-DT: A Comprehensive Analysis of a Potential LncRNA Biomarker and Its Regulatory Mechanisms in Gliomas.
Huang R; Kong Y; Luo Z; Li Q
Genes (Basel); 2024 Apr; 15(4):. PubMed ID: 38674418
[TBL] [Abstract] [Full Text] [Related]
8. PUMC-MB1 is a novel group 3 medulloblastoma preclinical model, sensitive to pi3k/mTOR dual inhibitor.
Wang S; Zhang D; Wang J; Peng X; Sun H; Ji Y; Yang Z; Bian X; Hou Y; Ge M; Liu Y
J Neurooncol; 2024 May; 168(1):139-149. PubMed ID: 38662151
[TBL] [Abstract] [Full Text] [Related]
9. Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients.
Dvorakova K; Skarkova V; Vitovcova B; Soukup J; Vosmikova H; Pleskacova Z; Skarka A; Bartos MC; Krupa P; Kasparova P; Petera J; Rudolf E
BMC Cancer; 2024 Apr; 24(1):509. PubMed ID: 38654280
[TBL] [Abstract] [Full Text] [Related]
10. Modulating DNA damage response in uveal melanoma through embryonic stem cell microenvironment.
Zhang Y; Zheng J; Chen M; Zhao S; Ma R; Chen W; Liu J
BMC Cancer; 2024 Apr; 24(1):519. PubMed ID: 38654216
[TBL] [Abstract] [Full Text] [Related]
11. Identification of core genes of craniopharyngioma angiogenesis based on single-cell nuclear transcriptome sequencing.
Zhang J; Xu L; Ye J; Xu C; Wu B; Wu J; Hong T
Cell Mol Biol (Noisy-le-grand); 2024 Mar; 70(3):136-141. PubMed ID: 38650143
[TBL] [Abstract] [Full Text] [Related]
12. Multi-omics technologies and molecular biomarkers in brain tumor-related epilepsy.
Du Y; Li R; Fu D; Zhang B; Cui A; Shao Y; Lai Z; Chen R; Chen B; Wang Z; Zhang W; Chu L
CNS Neurosci Ther; 2024 Apr; 30(4):e14717. PubMed ID: 38641945
[TBL] [Abstract] [Full Text] [Related]
13. Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors.
Cheng Y; Dai Y; Tang H; Lu X; Xie J; Xie W; Zhang Q; Liu Y; Lin S; Yao H; Shang H; Yang K; Liu H; Wu X; Zhang J; Zhang X; Xue L; Wu ZB
Acta Neuropathol Commun; 2024 Apr; 12(1):61. PubMed ID: 38637883
[TBL] [Abstract] [Full Text] [Related]
14. Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.
Li W; Zheng C; Xu X; Xia Y; Zhang K; Huang A; Zhang X; Zheng Y; Chen G; Zhang S
Cell Mol Biol Lett; 2024 Apr; 29(1):50. PubMed ID: 38594618
[TBL] [Abstract] [Full Text] [Related]
15. The interplay between autophagy and ferroptosis presents a novel conceptual therapeutic framework for neuroendocrine prostate cancer.
Wang Y; Wu N; Li J; Liang J; Zhou D; Cao Q; Li X; Jiang N
Pharmacol Res; 2024 May; 203():107162. PubMed ID: 38554788
[TBL] [Abstract] [Full Text] [Related]
16. WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.
Ji Q; Guo Y; Li Z; Zhang X
Aging (Albany NY); 2024 Mar; 16(6):5601-5617. PubMed ID: 38535989
[TBL] [Abstract] [Full Text] [Related]
17. Mechanism interpretation of Guhan Yangshengjing for protection against Alzheimer's disease by network pharmacology and molecular docking.
Cheung S; Zhong Y; Wu L; Jia X; He MQ; Ai Y; Jiao Q; Liang Q
J Ethnopharmacol; 2024 Jun; 328():117976. PubMed ID: 38492794
[TBL] [Abstract] [Full Text] [Related]
18. Natural products and derivatives in renal, urothelial and testicular cancers: Targeting signaling pathways and therapeutic potential.
Li D; Wang J; Tuo Z; Yoo KH; Yu Q; Miyamoto A; Zhang C; Ye X; Wei W; Wu R; Feng D
Phytomedicine; 2024 May; 127():155503. PubMed ID: 38490077
[TBL] [Abstract] [Full Text] [Related]
19. Discrete Mechanistic Target of Rapamycin Signaling Pathways, Stem cells, and Therapeutic Targets.
Jhanwar-Uniyal M; Zeller SL; Spirollari E; Das M; Hanft SJ; Gandhi CD
Cells; 2024 Feb; 13(5):. PubMed ID: 38474373
[TBL] [Abstract] [Full Text] [Related]
20. Identification of Key Molecular Pathways and Associated Genes as Targets to Overcome Radiotherapy Resistance Using a Combination of Radiotherapy and Immunotherapy in Glioma Patients.
Zhang T; Zhang Q; He X; Lu Y; Shao A; Sun X; Shao Y
Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474320
[TBL] [Abstract] [Full Text] [Related]
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