Terms: = Head and neck cancer AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Treatment
942 results:
1. DNMT1-targeting remodeling global DNA hypomethylation for enhanced tumor suppression and circumvented toxicity in oral squamous cell carcinoma.
Liu Y; Sun Y; Yang J; Wu D; Yu S; Liu J; Hu T; Luo J; Zhou H
Mol Cancer; 2024 May; 23(1):104. PubMed ID: 38755637
[TBL] [Abstract] [Full Text] [Related]
2. Campothecin suppresses cell proliferation and migration in head and neck squamous cell carcinoma by blocking RAB27A-mediated phosphatidylinositol 3 kinase (pi3k)/protein kinase B (AKT) pathway.
Zhao Y; Wang Y; Zhao L; Qu L; Zheng JH
J Physiol Pharmacol; 2024 Apr; 75(2):205-213. PubMed ID: 38736267
[TBL] [Abstract] [Full Text] [Related]
3. HMGA1 sensitizes esophageal squamous cell carcinoma to mTOR inhibitors through the ETS1-FKBP12 axis.
Guo JR; He KY; Yuan JL; An W; Yin WT; Li QT; Lu LY; Yang JY; Liu MJ; Li YJ; Zhao Y; Yang Q; Lei XY; Gao F; Zhang L; Wu DH; Li JQ; Zhao ZL; Liu H; Zhu LJ; Xiang XY; Sun QH; Jian YP; Xu ZX
Int J Biol Sci; 2024; 20(7):2640-2657. PubMed ID: 38725843
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4. Biological functions of LncRNA SNHG14 in the development of thyroid cancer cells via targeting miR-206.
Sang Y; Min R; Huang T; Zhang J
Cell Mol Biol (Noisy-le-grand); 2024 Apr; 70(4):77-84. PubMed ID: 38678623
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5. Curcumin Alone and Combined With pi3k Inhibitors Elicits Positive Effects on Oropharyngeal cancer Cell Lines Regardless of HPV Status.
Lukoceviciute M; Zupancic M; Kostopoulou ON; Holzhauser S; Dalianis T
Anticancer Res; 2024 May; 44(5):1863-1876. PubMed ID: 38677772
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6. Differences in the response of normal oral mucosa, oral leukoplakia, oral squamous cell carcinoma-derived mesenchymal stem cells, and epithelial cells to photodynamic therapy.
Guo Q; Ji X; Zhang L; Liu X; Wang Y; Liu Z; Jin J; Han Y; Liu H
J Photochem Photobiol B; 2024 Jun; 255():112907. PubMed ID: 38677259
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7. Dexrazoxane inhibits the growth of esophageal squamous cell carcinoma by attenuating SDCBP/MDA-9/syntenin-mediated EGFR-pi3k-Akt pathway activation.
Du R; Xiao N; Han L; Guo K; Li K; Chen Z; Zhang H; Zhou Z; Huang Y; Zhao X; Bian H
Sci Rep; 2024 Apr; 14(1):9167. PubMed ID: 38649770
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8. Phase II study of novel orally pi3kα/δ inhibitor TQ-B3525 in relapsed and/or refractory follicular lymphoma.
Wang H; Feng J; Liu Y; Qian Z; Gao D; Ran X; Zhou H; Liu L; Wang B; Fang M; Zhou H; Huang Z; Tao S; Chen Z; Su L; Su H; Yang Y; Xie X; Wu H; Sun P; Hu G; Liang A; Li Z
Signal Transduct Target Ther; 2024 Apr; 9(1):99. PubMed ID: 38627366
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9. PQR309, a dual pi3k/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma.
Cao J; Zeng K; Chen Q; Yang T; Lu F; Lin C; Zhan J; Ma W; Zhou T; Huang Y; Luo F; Zhao H
Cell Death Dis; 2024 Mar; 15(3):237. PubMed ID: 38555280
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10. The emerging role and clinical significance of circRNAs in papillary thyroid cancer.
Ma J; Xu J; Zhang X; Quan J
Front Endocrinol (Lausanne); 2024; 15():1351776. PubMed ID: 38544689
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11. Microbiome Dysbiosis Is Associated with Castration Resistance and cancer Stemness in Metastatic Prostate cancer.
Uzelac M; Xin R; Ongkeko WM
Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542265
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12. ADAM22 acts as a novel predictive biomarker for unfavorable prognosis and facilitates metastasis via pi3k/AKT signaling pathway in nasopharyngeal carcinoma.
Xu K; Jiang P; Chen Z; Gu X; Zhang T
Pathol Res Pract; 2024 Apr; 256():155264. PubMed ID: 38518731
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13. Tyrosine phosphatase
Chen X; Keller SJ; Hafner P; Alrawashdeh AY; Avery TY; Norona J; Zhou J; Ruess DA
Front Immunol; 2024; 15():1340726. PubMed ID: 38504984
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14. The antitumor effects of herbal medicine Triphala on oral cancer by inactivating pi3k/Akt signaling pathway: based on the network pharmacology, molecular docking, in vitro and in vivo experimental validation.
Hu S; Li S; Xu Y; Huang X; Mai Z; Chen Y; Xiao H; Ning W; Gaus S; Savkovic V; Lethaus B; Zimmerer R; Acharya A; Ziebolz D; Schmalz G; Huang S; Zhao J; Hu X
Phytomedicine; 2024 Jun; 128():155488. PubMed ID: 38493718
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15. Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma.
Wang WP; Shi D; Yun D; Hu J; Wang JF; Liu J; Yang YP; Li MR; Wang JF; Kong DL
World J Gastroenterol; 2024 Feb; 30(6):565-578. PubMed ID: 38463028
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16. Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses.
Xiao Y; Xu B; Li X; Ding T; Zhao W; Nie X; Mu J; Xiao Z; Wang Q; Ren Q; Zhang E
Steroids; 2024 May; 205():109393. PubMed ID: 38458369
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17. Impact of pik3ca and cell cycle pathway genetic alterations on durvalumab efficacy in patients with head and neck squamous cell carcinoma: Post hoc analysis of TRIUMPH study.
Kim DH; Lim ST; Kim HR; Kang EJ; Ahn HK; Lee YG; Sun S; Kwon JH; Lee SC; Lee HW; Kim MK; Keam B; Park KU; Shin SH; Yun HJ
Oral Oncol; 2024 Apr; 151():106739. PubMed ID: 38458039
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18. The mechanism and experimental verification of Ixeris sonchifolia promoting apoptosis of hepatocellular carcinoma based on network pharmacology: Ixeris sonchifolia Induces Hepatocellular Carcinoma Apoptosis via the pi3k/AKT Pathway.
Liu BJ; Guan YY; Qiao LX; Zhang JM; Li AJ; Yang PX; Gao YX; Chen DX; Wang CX; Wu J
J Ethnopharmacol; 2024 Jun; 327():117994. PubMed ID: 38437889
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19. [Clinicopathological and molecular characteristics of esophageal carcinoma with ductal differentiation: analysis of 17 cases].
Jiang WJ; Ao S; Cui YY; Lu L; Wang CN
Zhonghua Bing Li Xue Za Zhi; 2024 Mar; 53(3):276-281. PubMed ID: 38433056
[No Abstract] [Full Text] [Related]
20. Differential modulation of pi3k/Akt/mTOR activity by EGFR inhibitors: A rationale for co-targeting EGFR and pi3k in cisplatin-resistant HNSCC.
Liao J; Yang Z; Azarbarzin S; Cullen KJ; Dan H
Head Neck; 2024 May; 46(5):1126-1135. PubMed ID: 38429897
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