BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND AFF1, MLLT2, 4299, ENSG00000172493, P51825, AF-4, PBM1
104 results:

  • 1. Lineage switch of KMT2A-rearranged adult B-lineage acute lymphoblastic leukemia following bispecific T-cell engager and monoclonal antibody therapy.
    Wu JR; Shih PC; Li C; Chao HL; Wang HC; Chiang YM; Liu YJ; Hsu SC; Yao CY; Chen LH; Lin CC; Tien HF; Chou WC
    J Hematop; 2023 Jun; 16(2):103-109. PubMed ID: 38175441
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Four Additional Doses of PEG-L-Asparaginase During the Consolidation Phase in the AIEOP-BFM ALL 2009 Protocol Do Not Improve Outcome and Increase Toxicity in High-Risk ALL: Results of a Randomized Study.
    Conter V; Valsecchi MG; Cario G; Zimmermann M; Attarbaschi A; Stary J; Niggli F; Dalla Pozza L; Elitzur S; Silvestri D; Locatelli F; Möricke A; Engstler G; Smisek P; Bodmer N; Barbaric D; Izraeli S; Rizzari C; Boos J; Buldini B; Zucchetti M; von Stackelberg A; Matteo C; Lehrnbecher T; Lanvers-Kaminsky C; Cazzaniga G; Gruhn B; Biondi A; Schrappe M
    J Clin Oncol; 2024 Mar; 42(8):915-926. PubMed ID: 38096462
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::aff1 fusion.
    Tretti Parenzan C; Molin AD; Longo G; Gaffo E; Buratin A; Cani A; Boldrin E; Serafin V; Guglielmelli P; Vannucchi AM; Cazzaniga G; Biondi A; Locatelli F; Meyer LH; Buldini B; Te Kronnie G; Bresolin S; Bortoluzzi S
    Blood Adv; 2024 Mar; 8(5):1305-1319. PubMed ID: 38029383
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Genome editing-induced t(4;11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-aff1 fusion.
    Pan F; Sarno J; Jeong J; Yang X; Jager A; Gruber TA; Davis KL; Cleary ML
    J Clin Invest; 2024 Jan; 134(1):. PubMed ID: 37917159
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A surrogate molecular approach for the detection of Philadelphia chromosome-like B-acute lymphoblastic leukemia.
    Gupta DG; Varma N; Abdulkadir SA; Sreedharanunni S; Sachdeva MUS; Naseem S; Bose P; Binota J; Malhotra P; Khadwal A; Trehan A; Varma S
    Cancer; 2024 Mar; 130(5):713-726. PubMed ID: 37819686
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Generation of a human induced pluripotent stem cell line harboring the infant leukemia-associated fusion gene, KMT2A-aff1 (IMSUTi002-A-2).
    Takahashi M
    Stem Cell Res; 2023 Sep; 71():103185. PubMed ID: 37639801
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. AFF4 globally affects the release of paused RNA polymerase II in HEL cells.
    Yang ZM; Zhang G; Wei G; Jing LL; Yu M
    Yi Chuan; 2023 Aug; 45(8):658-668. PubMed ID: 37609817
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.
    Külp M; Larghero P; Alten J; Cario G; Eckert C; Caye-Eude A; Cavé H; Schmachtel T; Bardini M; Cazzaniga G; De Lorenzo P; Valsecchi MG; Bonig H; Meyer C; Rieger MA; Marschalek R
    Leukemia; 2023 Jun; 37(6):1216-1233. PubMed ID: 37100882
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A comprehensive landscape of transcription profiles and data resources for human leukemia.
    Luo M; Miao YR; Ke YJ; Guo AY; Zhang Q
    Blood Adv; 2023 Jul; 7(14):3435-3449. PubMed ID: 36595475
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Discovery of fusion circular RNAs in leukemia with KMT2A::aff1 rearrangements by the new software CircFusion.
    Dal Molin A; Tretti Parenzan C; Gaffo E; Borin C; Boldrin E; Meyer LH; Te Kronnie G; Bresolin S; Bortoluzzi S
    Brief Bioinform; 2023 Jan; 24(1):. PubMed ID: 36585787
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. KMT2A-D pathogenicity, prevalence, and variation according to a population database.
    Larson JK; Hunter-Schlichting DN; Crowgey EL; Mills LJ; Druley TE; Marcotte EL
    Cancer Med; 2023 Mar; 12(6):7234-7245. PubMed ID: 36479909
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
    Isobe T; Takagi M; Sato-Otsubo A; Nishimura A; Nagae G; Yamagishi C; Tamura M; Tanaka Y; Asada S; Takeda R; Tsuchiya A; Wang X; Yoshida K; Nannya Y; Ueno H; Akazawa R; Kato I; Mikami T; Watanabe K; Sekiguchi M; Seki M; Kimura S; Hiwatari M; Kato M; Fukuda S; Tatsuno K; Tsutsumi S; Kanai A; Inaba T; Shiozawa Y; Shiraishi Y; Chiba K; Tanaka H; Kotecha RS; Cruickshank MN; Ishikawa F; Morio T; Eguchi M; Deguchi T; Kiyokawa N; Arakawa Y; Koh K; Aoki Y; Ishihara T; Tomizawa D; Miyamura T; Ishii E; Mizutani S; Wilson NK; Göttgens B; Miyano S; Kitamura T; Goyama S; Yokoyama A; Aburatani H; Ogawa S; Takita J
    Nat Commun; 2022 Aug; 13(1):4501. PubMed ID: 36042201
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Poor treatment responses were related to poor outcomes in pediatric B cell acute lymphoblastic leukemia with KMT2A rearrangements.
    Wen J; Zhou M; Shen Y; Long Y; Guo Y; Song L; Xiao J
    BMC Cancer; 2022 Aug; 22(1):859. PubMed ID: 35933338
    [TBL] [Abstract] [Full Text] [Related]  

  • 14.
    Forgione MO; McClure BJ; Page EC; Yeung DT; Eadie LN; White DL
    Oncol Rep; 2022 May; 47(5):. PubMed ID: 35323988
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study.
    Moorman AV; Barretta E; Butler ER; Ward EJ; Twentyman K; Kirkwood AA; Enshaei A; Schwab C; Creasey T; Leongamornlert D; Papaemmanuil E; Patrick P; Clifton-Hadley L; Patel B; Menne T; McMillan AK; Harrison CJ; Rowntree CJ; Marks DI; Fielding AK
    Leukemia; 2022 Mar; 36(3):625-636. PubMed ID: 34657128
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Genetic and Epigenetic Characterization of a Discordant
    Russo A; Viberti C; Mareschi K; Casalone E; Guarrera S; Birolo G; Cazzaniga G; Corral L; Trentin L; Basso G; Fagioli F; Matullo G
    Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34575904
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experience.
    Richard-Carpentier G; Kantarjian HM; Tang G; Yin CC; Khoury JD; Issa GC; Haddad F; Jain N; Ravandi F; Short NJ; DiNardo CD; Takahashi K; Konopleva MY; Daver NG; Kadia T; Garcia-Manero G; Garris R; O'Brien S; Jabbour E
    Blood Adv; 2021 Dec; 5(23):5415-5419. PubMed ID: 34525185
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. [Acute leukemia of infants and neonates].
    Eguchi M
    Rinsho Ketsueki; 2021; 62(8):1308-1318. PubMed ID: 34497221
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [Leukemogenic pathway of infant leukemia with MLL fusion].
    Eguchi M
    Rinsho Ketsueki; 2021; 62(7):809-819. PubMed ID: 34349066
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Molecular classification improves risk assessment in adult BCR-ABL1-negative B-ALL.
    Paietta E; Roberts KG; Wang V; Gu Z; Buck GAN; Pei D; Cheng C; Levine RL; Abdel-Wahab O; Cheng Z; Wu G; Qu C; Shi L; Pounds S; Willman CL; Harvey R; Racevskis J; Barinka J; Zhang Y; Dewald GW; Ketterling RP; Alejos D; Lazarus HM; Luger SM; Foroni L; Patel B; Fielding AK; Melnick A; Marks DI; Moorman AV; Wiernik PH; Rowe JM; Tallman MS; Goldstone AH; Mullighan CG; Litzow MR
    Blood; 2021 Sep; 138(11):948-958. PubMed ID: 33895809
    [TBL] [Abstract] [Full Text] [Related]  


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