Terms: = Leukemia AND ARHGEF12, Q9NZN5, 23365, ENSG00000196914, KIAA0382, LARG, DKFZp686O2372, PRO2792
56 results:
1. KMT2A-arhgef12, a therapy related fusion with poor prognosis.
Assaf N; Liévin R; Merabet F; Raggueneau V; Osman J; Kim R; Garnache F; D'Angiò M; Larghero P; Meyer C; Marschalek R; Rousselot P; Terré C
Mol Biol Rep; 2021 Oct; 48(10):7021-7027. PubMed ID: 34383244
[TBL] [Abstract] [Full Text] [Related]
2. Regulation of Leukaemia Associated Rho GEF (larg/arhgef12).
Ghanem NZ; Matter ML; Ramos JW
Small GTPases; 2022 Jan; 13(1):196-204. PubMed ID: 34304710
[TBL] [Abstract] [Full Text] [Related]
3. Identification of KMT2A-arhgef12 fusion in a child with a high-grade B-cell lymphoma.
Schafernak KT; Williams JA; Clyde BI; Marcus C; Decker B; Toydemir RM
Cancer Genet; 2021 Nov; 258-259():23-26. PubMed ID: 34237703
[TBL] [Abstract] [Full Text] [Related]
4. Therapy-induced Deletion in 11q23 Leading to Fusion of
Panagopoulos I; Andersen K; Eilert-Olsen M; Zeller B; Munthe-Kaas MC; Buechner J; Osnes LTN; Micci F; Heim S
Cancer Genomics Proteomics; 2021; 18(1):67-81. PubMed ID: 33419897
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5. leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance.
Ding Z; Dong Z; Yang Y; Fortin Ensign SP; Sabit H; Nakada M; Ruggieri R; Kloss JM; Symons M; Tran NL; Loftus JC
Am J Pathol; 2020 Oct; 190(10):2165-2176. PubMed ID: 32693062
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6. arhgef12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients.
Xie Y; Gao L; Xu C; Chu L; Gao L; Wu R; Liu Y; Liu T; Sun XJ; Ren R; Tang J; Zheng Y; Zhou Y; Shen S
Haematologica; 2020 Apr; 105(4):925-936. PubMed ID: 31467124
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7. A Nonpump Function of Sodium Iodide Symporter in Thyroid Cancer via Cross-talk with PTEN Signaling.
Feng F; Yehia L; Ni Y; Chang YS; Jhiang SM; Eng C
Cancer Res; 2018 Nov; 78(21):6121-6133. PubMed ID: 30217930
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8. RSK2 drives cell motility by serine phosphorylation of larg and activation of Rho GTPases.
Shi GX; Yang WS; Jin L; Matter ML; Ramos JW
Proc Natl Acad Sci U S A; 2018 Jan; 115(2):E190-E199. PubMed ID: 29279389
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9. Potentiation of receptor responses induced by prolonged binding of Gα
Bodmann EL; Krett AL; Bünemann M
FASEB J; 2017 Aug; 31(8):3663-3676. PubMed ID: 28465324
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10. Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα
Scherer SL; Cain MD; Kanai SM; Kaltenbronn KM; Blumer KJ
J Biol Chem; 2017 Jun; 292(24):9906-9918. PubMed ID: 28432124
[TBL] [Abstract] [Full Text] [Related]
11. The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination With Cell Polarization During Ameloblast Differentiation.
Otsu K; Ida-Yonemochi H; Fujiwara N; Harada H
J Bone Miner Res; 2016 Nov; 31(11):1943-1954. PubMed ID: 27218883
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12. Leukaemia-associated Rho guanine nucleotide exchange factor (larg) plays an agonist specific role in platelet function through RhoA activation.
Zou S; Teixeira AM; Yin M; Xiang Y; Xavier-Ferrucio J; Zhang PX; Hwa J; Min W; Krause DS
Thromb Haemost; 2016 Aug; 116(3):506-16. PubMed ID: 27345948
[TBL] [Abstract] [Full Text] [Related]
13. Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (larg) by Cdk1.
Helms MC; Grabocka E; Martz MK; Fischer CC; Suzuki N; Wedegaertner PB
Cell Signal; 2016 Jan; 28(1):43-52. PubMed ID: 26483157
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14. A population-based single nucleotide polymorphism array analysis of genomic aberrations in younger adult acute lymphoblastic leukemia patients.
Dirse V; Bertasiute A; Gineikiene E; Zvirblis T; Dambrauskiene R; Gerbutavicius R; Juozaityte E; Malciute L; Paulsson K; Griskevicius L
Genes Chromosomes Cancer; 2015 May; 54(5):326-33. PubMed ID: 25706938
[TBL] [Abstract] [Full Text] [Related]
15. The leukemia-associated Rho guanine nucleotide exchange factor larg is required for efficient replication stress signaling.
Beveridge RD; Staples CJ; Patil AA; Myers KN; Maslen S; Skehel JM; Boulton SJ; Collis SJ
Cell Cycle; 2014; 13(21):3450-9. PubMed ID: 25485589
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16. The RhoA guanine nucleotide exchange factor, larg, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
Lessey-Morillon EC; Osborne LD; Monaghan-Benson E; Guilluy C; O'Brien ET; Superfine R; Burridge K
J Immunol; 2014 Apr; 192(7):3390-8. PubMed ID: 24585879
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17. Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.
Artamonov MV; Momotani K; Stevenson A; Trentham DR; Derewenda U; Derewenda ZS; Read PW; Gutkind JS; Somlyo AV
J Biol Chem; 2013 Nov; 288(47):34030-34040. PubMed ID: 24106280
[TBL] [Abstract] [Full Text] [Related]
18. The activation of RhoC in vascular endothelial cells is required for the S1P receptor type 2-induced inhibition of angiogenesis.
Del Galdo S; Vettel C; Heringdorf DM; Wieland T
Cell Signal; 2013 Dec; 25(12):2478-84. PubMed ID: 23993968
[TBL] [Abstract] [Full Text] [Related]
19. leukemia-associated RhoGEF (larg) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.
Martz MK; Grabocka E; Beeharry N; Yen TJ; Wedegaertner PB
Mol Biol Cell; 2013 Sep; 24(18):2785-94. PubMed ID: 23885121
[TBL] [Abstract] [Full Text] [Related]
20. Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.
Chow CR; Suzuki N; Kawamura T; Hamakubo T; Kozasa T
Cell Signal; 2013 Nov; 25(11):2085-92. PubMed ID: 23816534
[TBL] [Abstract] [Full Text] [Related]
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